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Medicine

D-Index
115
Citations
48241
World Ranking
4553
National Ranking
177

Overview

Eric Bouffet is affiliated with the University of Toronto in Canada. Their research primarily focuses on medicine, with significant contributions in genetics, neurology, molecular biology, pulmonary and respiratory medicine, and pediatrics, perinatology, and child health.

The scientist's work has concentrated on several key topics, which include:

  • Glioma diagnosis and treatment
  • Neuroblastoma research and treatments
  • Childhood cancer survivors' quality of life
  • Neurofibromatosis and schwannoma cases
  • Meningioma and schwannoma management
  • Cancer genomics and diagnostics
  • Brain metastases and treatment

Eric Bouffet has authored numerous papers, with some recent notable publications being:

  • Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas (2020) in Cancer Cell
  • Sustainable care for children with cancer: a Lancet Oncology Commission (2020) in The Lancet Oncology
  • Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group (2020) in The Lancet Oncology
  • Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03) (2021) in Journal of Clinical Oncology
  • Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations (2023) in New England Journal of Medicine

Frequent coauthors collaborating with Eric Bouffet include:

  • Uri Tabori
  • Cynthia Hawkins
  • Vijay Ramaswamy
  • Ute Bartels
  • Derek S. Tsang

Their research has been published extensively in specialized venues, reflecting their focus on neuro-oncology and pediatric oncology. Common publication venues are:

  • Neuro-Oncology
  • Pediatric Blood & Cancer
  • Journal of Clinical Oncology
  • Journal of Neuro-Oncology
  • Neuro-Oncology Advances

Overall, Eric Bouffet's research spans across clinical and molecular aspects of pediatric cancers, with particular emphasis on gliomas and related tumor types. Their collaborative work, interdisciplinary approach, and extensive scholarly output contribute to a substantial body of knowledge in pediatric neuro-oncology. The scientist remains an active contributor to advancements in cancer research and treatment methodologies.

Best Publications

  • Medulloblastoma Comprises Four Distinct Molecular Variants

    Paul A. Northcott;Andrey Korshunov;Hendrik Witt;Thomas Hielscher

  • Intertumoral Heterogeneity within Medulloblastoma Subgroups

    Florence M.G. Cavalli;Marc Remke;Marc Remke;Marc Remke;Ladislav Rampasek;John Peacock

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.

    Dong Anh Khuong-Quang;Pawel Buczkowicz;Patricia Rakopoulos;Xiao Yang Liu

  • Novel mutations target distinct subgroups of medulloblastoma

    Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu

  • Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency

    Eric Bouffet;Valérie Larouche;Brittany B. Campbell;Daniele Merico

  • Comprehensive Analysis of Hypermutation in Human Cancer

    Brittany B. Campbell;Nicholas Light;David Fabrizio;Matthew Zatzman

  • Diffuse brainstem glioma in children: critical review of clinical trials

    Darren Hargrave;Ute Bartels;Eric Bouffet

  • Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

    Pawel Buczkowicz;Christine Hoeman;Patricia Rakopoulos;Sanja Pajovic

  • Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

    S. C. Mack;H. Witt;R. M. Piro;L. Gu

  • Risk stratification of childhood medulloblastoma in the molecular era: the current consensus

    Vijay Ramaswamy;Marc Remke;Eric Bouffet;Simon Bailey

  • Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

    Nataliya Zhukova;Vijay Ramaswamy;Marc Remke;Elke Pfaff

  • Change in Neurocognitive Functioning After Treatment With Cranial Radiation in Childhood

    Brenda J. Spiegler;Eric Bouffet;Mark L. Greenberg;James T. Rutka

  • Clonal selection drives genetic divergence of metastatic medulloblastoma

    Xiaochong Wu;Paul A. Northcott;Adrian Dubuc;Adam J. Dupuy

  • Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

    Paul A. Northcott;David J H Shih;Marc Remke;Marc Remke;Yoon-Jae Cho

  • Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

    Lindsey M. Hoffman;Sophie E.M.Veldhuijzen Van Zanten;Niclas Colditz;Joshua Baugh

  • Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

    Vijay Ramaswamy;Marc Remke;Eric Bouffet;Claudia C. Faria

  • Whole-Genome Profiling of Pediatric Diffuse Intrinsic Pontine Gliomas Highlights Platelet-Derived Growth Factor Receptor α and Poly (ADP-ribose) Polymerase As Potential Therapeutic Targets

    Maryam Zarghooni;Ute Bartels;Eric Lee;Pawel Buczkowicz

  • Divergent clonal selection dominates medulloblastoma at recurrence

    A. Sorana Morrissy;Livia Garzia;David J.H. Shih;Scott Zuyderduyn

  • Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

    Adam Shlien;Brittany B Campbell;Richard de Borja;Ludmil B Alexandrov

Frequent Co-Authors

Cynthia Hawkins
Cynthia Hawkins University of Toronto
Uri Tabori
Uri Tabori University of Toronto
Michael D. Taylor
Michael D. Taylor University of Toronto
Vijay Ramaswamy
Vijay Ramaswamy University of Toronto
Peter B. Dirks
Peter B. Dirks University of Toronto
James T. Rutka
James T. Rutka University of Toronto
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Nada Jabado
Nada Jabado McGill University
Marc Remke
Marc Remke German Cancer Research Center
Roger J. Packer
Roger J. Packer Children’s National Health System

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