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Overview

Jacques Grill is affiliated with the Institut Gustave Roussy in France. Their research predominantly focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with extensive work in the subfields of Genetics, Molecular Biology, Neurology, Radiology, Nuclear Medicine and Imaging, and Pulmonary and Respiratory Medicine.

The scientist's principal areas of research include Glioma Diagnosis and Treatment, Neuroblastoma Research and Treatments, Chromatin Remodeling and Cancer, Meningioma and Schwannoma Management, Vascular Malformations Diagnosis and Treatment, Neurofibromatosis and Schwannoma Cases, and Cancer Genomics and Diagnostics.

Jacques Grill has contributed to numerous publications in various scientific venues. The most frequent publication outlets include:

  • Neuro-Oncology
  • Acta Neuropathologica Communications
  • Neuro-Oncology Advances
  • Cancer Discovery
  • European Radiology

Some notable recent papers by Jacques Grill are:

  • "Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation" (2020, Acta Neuropathologica)
  • "iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer" (2023, Nature)
  • "Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways" (2023, Cancer Discovery)
  • "A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR" (2020, Neuro-Oncology)
  • "High-grade gliomas in adolescents and young adults highlight histomolecular differences from their adult and pediatric counterparts" (2020, Neuro-Oncology)

Jacques Grill frequently collaborates with several co-authors, including:

  • Pascale Varlet (55 publications)
  • Kévin Beccaria (45 publications)
  • Nathalie Boddaert (36 publications)
  • Thomas Blauwblomme (36 publications)
  • Volodia Dangouloff-Ros (34 publications)

Best Publications

  • New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

    Dominik Sturm;Dominik Sturm;Brent A. Orr;Umut H. Toprak;Volker Hovestadt

  • Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

    Alan Mackay;Anna Burford;Diana Carvalho;Elisa Izquierdo

  • Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

    Sebastian Bender;Sebastian Bender;Yujie Tang;Anders M. Lindroth;Volker Hovestadt

  • Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

    Catherine S. Grasso;Yujie Tang;Yujie Tang;Nathalene Truffaux;Noah E. Berlow

  • Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

    Dominik Sturm;Sebastian Bender;David T. W. Jones;Peter Lichter

  • Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.

    David Castel;Cathy Philippe;Raphaël Calmon;Ludivine Le Dret

  • Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

    Kathryn R Taylor;Alan Mackay;Nathalène Truffaux;Yaron S Butterfield

  • Pediatric craniopharyngiomas: classification and treatment according to the degree of hypothalamic involvement.

    Stéphanie Puget;Matthew Garnett;Alison Wray;Jacques Grill

  • Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

    Lindsey M. Hoffman;Sophie E.M.Veldhuijzen Van Zanten;Niclas Colditz;Joshua Baugh

  • Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes.

    Jacques Grill;Virginie Kieffer Renaux;Christine Bulteau;Delphine Viguier

  • Survival and Prognostic Factors of Early Childhood Medulloblastoma: An International Meta-Analysis

    Stefan Rutkowski;Katja Von Hoff;Angela Emser;Isabella Zwiener

  • Postoperative Chemotherapy Without Irradiation for Ependymoma in Children Under 5 Years of Age: A Multicenter Trial of the French Society of Pediatric Oncology

    Jacques Grill;Marie-Cécile Le Deley;Danièle Gambarelli;Marie-Anne Raquin

  • Prognostic factors of CNS tumours in Neurofibromatosis 1 (NF1): a retrospective study of 104 patients.

    Jean-Sébastien Guillamo;Alain Créange;Chantal Kalifa;Jacques Grill

  • Treatment of medulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children

    Jacques Grill;Christian Sainte-Rose;Anne Jouvet;Jean-Claude Gentet

  • Histopathological grading of pediatric ependymoma: Reproducibility and clinical relevance in European trial cohorts

    David W Ellison;Mehmet Kocak;Dominique Figarella-Branger;Giangaspero Felice

  • MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.

    Pratiti Bandopadhayay;Pratiti Bandopadhayay;Lori A Ramkissoon;Payal Jain;Guillaume Bergthold;Guillaume Bergthold

  • Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.

    Stephanie Puget;Cathy Philippe;Dorine A. Bax;Bastien Job

  • Radiation-induced cerebral vasculopathy in children with neurofibromatosis and optic pathway glioma

    J. Grill;D. Couanet;C. Cappelli;J. L. Habrand

  • Potential of the Conditionally Replicative Adenovirus Ad5-Δ24RGD in the Treatment of Malignant Gliomas and Its Enhanced Effect with Radiotherapy

    Martine L.M. Lamfers;Jacques Grill;Clemens M.F. Dirven;Victor W. Van Beusechem

  • Stereotactic biopsy of diffuse pontine lesions in children.

    Thomas Roujeau;Guilherme Machado;Matthew R. Garnett;Catherine Miquel

Frequent Co-Authors

Gilles Vassal
Gilles Vassal Institut Gustave Roussy
Nathalie Boddaert
Nathalie Boddaert Université Paris Cité
Chris Jones
Chris Jones Institute of Cancer Research
François Doz
François Doz Université Paris Cité
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Laurence Brugières
Laurence Brugières Institut Gustave Roussy
Georges Dellatolas
Georges Dellatolas Grenoble Alpes University
Torsten Pietsch
Torsten Pietsch University of Bonn
David T. W. Jones
David T. W. Jones German Cancer Research Center
Cynthia Hawkins
Cynthia Hawkins University of Toronto

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