World's Best Scientists 2026 revealed!
Laurence Brugières

Laurence Brugières

D-Index & Metrics

Medicine

D-Index
85
Citations
25769
World Ranking
14638
National Ranking
471

Overview

Laurence Brugières is affiliated with the Institut Gustave Roussy in France and has contributed extensively to the fields of medicine and molecular biology. Their research encompasses a wide range of specialties including pathology and forensic medicine, oncology, pulmonary and respiratory medicine, and cancer research.

Their work covers several main topics such as lymphoma diagnosis and treatment, cancer genomics and diagnostics, genetic factors in colorectal cancer, sarcoma diagnosis and treatment, lung cancer treatments and mutations, childhood cancer survivors' quality of life, and studies on the Hedgehog signaling pathway.

Among Laurence Brugières' recent publications are:

  • Germline Elongator mutations in Sonic Hedgehog medulloblastoma, 2020, Nature
  • Diagnostic criteria for constitutional mismatch repair deficiency (CMMRD): recommendations from the international consensus working group, 2021, Journal of Medical Genetics
  • Predisposition to cancer in children and adolescents, 2021, The Lancet Child & Adolescent Health
  • Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer, 2021, Cancer Discovery
  • Prognostic Factors in Childhood Anaplastic Large Cell Lymphoma: Long Term Results of the International ALCL99 Trial, 2020, Cancers

Laurence Brugières frequently collaborates with other researchers in their field. Frequent coauthors include Léa Guerrini-Rousseau, Franck Bourdeaut, Charlotte Rigaud, Cécile Faure-Conter, and Andishe Attarbaschi.

Their research has been published primarily in journals such as Pediatric Blood & Cancer, Neuro-Oncology, Journal of Medical Genetics, Nature Medicine, and Cancers.

Best Publications

  • Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

    Isabelle Janoueix-Lerosey;Delphine Lequin;Delphine Lequin;Laurence Brugières;Agnès Ribeiro

  • ALK-Positive Lymphoma: A Single Disease With a Broad Spectrum of Morphology

    Daniel Benharroch;Zarouhie Meguerian-Bedoyan;Laurence Lamant;Chauki Amin

  • Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers

    Gaëlle Bougeard;Mariette Renaux-Petel;Jean-Michel Flaman;Camille Charbonnier

  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

    Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub

  • Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

    P.G. Casali;S. Bielack;N. Abecassis;H.T. Aro

  • Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer

    Stefano Cairo;Stefano Cairo;Carolina Armengol;Carolina Armengol;Aurélien de Reyniès;Yu. Wei;Yu. Wei

  • P53 germline mutations in childhood cancers and cancer risk for carrier individuals.

    A Chompret;L Brugières;M Ronsin;M Gardes

  • Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

    Christian P. Kratz;Maria Isabel Achatz;Laurence Brugieres;Thierry Frebourg

  • Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium ‘Care for CMMRD’ (C4CMMRD)

    Katharina Wimmer;Christian P Kratz;Hans F A Vasen;Olivier Caron

  • Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

    Sebastian M. Waszak;Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Giles W. Robinson

  • BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy

    Sébastien Héritier;Jean-François Emile;Mohamed-Aziz Barkaoui;Caroline Thomas

  • Sensitivity and predictive value of criteria for p53 germline mutation screening

    Agnès Chompret;Anne Abel;Dominique Stoppa-Lyonnet;Laurence Brugières

  • Successful Treatment of Childhood High-Risk Hepatoblastoma With Dose-Intensive Multiagent Chemotherapy and Surgery: Final Results of the SIOPEL-3HR Study

    József Zsíros;Rudolf Maibach;Elizabeth Shafford;Laurence Brugieres

  • Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma

    Giorgio Perilongo;Rudolf Maibach;Elisabeth Shafford;Laurence Brugieres

  • High incidence of the t(2;5)(p23;q35) translocation in anaplastic large cell lymphoma and its lack of detection in Hodgkin's disease. Comparison of cytogenetic analysis, reverse transcriptase-polymerase chain reaction, and P-80 immunostaining

    L Lamant;F Meggetto;T al Saati;L Brugieres

  • Risk-adapted treatment for childhood hepatoblastoma. final report of the second study of the International Society of Paediatric Oncology--SIOPEL 2.

    G. Perilongo;E. Shafford;R. Maibach;D. Aronson

  • CD30+ anaplastic large-cell lymphoma in children : Analysis of 82 patients enrolled in two consecutive studies of the French society of Pediatric Oncology

    L. Brugières;M.C. Le Deley;H. Pacquement;Z. Meguerian-Bedoyan

  • Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

    József Zsiros;Laurence Brugieres;Penelope Brock;Derek Roebuck

  • Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss

    Penelope R Brock;Rudolf Maibach;Margaret Childs;Kaukab Rajput

  • Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

    P.G. Casali;S. Bielack;N. Abecassis;H.T. Aro

Frequent Co-Authors

Jacques Grill
Jacques Grill Institut Gustave Roussy
Gilles Vassal
Gilles Vassal Institut Gustave Roussy
Thierry Frebourg
Thierry Frebourg Grenoble Alpes University
Olivier Delattre
Olivier Delattre PSL University
Alfred Reiter
Alfred Reiter University of Giessen
Georges Delsol
Georges Delsol Federal University of Toulouse Midi-Pyrénées
Odile Oberlin
Odile Oberlin Institut Gustave Roussy
François Doz
François Doz Université Paris Cité
Brigitte Bressac-de Paillerets
Brigitte Bressac-de Paillerets Institut Gustave Roussy
Jean Feunteun
Jean Feunteun Institut Gustave Roussy

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in medicine isn’t limited to traditional medical school. There are many phd nursing education online programs designed for those with advanced nursing goals. These online pathways can make it easier to balance your studies with work or family obligations.

Cost is another big factor for many students. Fortunately, there are options like the cheapest rn to bsn online programs, which can help registered nurses earn their bachelor’s degree more affordably and quickly advance their careers.

If you have a bachelor’s degree in another field but are interested in nursing, non nursing bachelor's to msn online programs offer accelerated paths to become a nurse at the master’s level. These programs are great for career changers seeking fast entry into healthcare.

Not all nursing schools have highly competitive admissions. You may want to consider easy nursing programs to get into if you wish to simplify your application process and begin your journey in medicine sooner.

Best Scientists Citing Laurence Brugières

Trending Scientists

Recently Published Articles