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Molecular Biology

D-Index
75
Citations
23254
World Ranking
1187
National Ranking
615

Overview

Stephan W. Morris is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Immunology, Pathology and Forensic Medicine, Cancer Research, Hematology, and Oncology.

Their work covers a range of topics including Acute Myeloid Leukemia Research, Lymphoma Diagnosis and Treatment, Protein Degradation and Inhibitors, Cancer Genomics and Diagnostics, T-cell and Retrovirus Studies, Cutaneous lymphoproliferative disorders research, and Microtubule and mitosis dynamics.

Stephan W. Morris has contributed to several recent publications, such as:

  • Gene Expression Signatures for the Accurate Diagnosis of Peripheral T-Cell Lymphoma Entities in the Routine Clinical Practice, 2022, Journal of Clinical Oncology
  • Covalent Menin Inhibitor Bmf-219 in Patients with Relapsed or Refractory (R/R) Acute Leukemia (AL): Preliminary Phase 1 Data from the Covalent-101 Study, 2023, Blood
  • Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes, 2022, Journal of Clinical Investigation
  • Complete remission of NUP98 fusion-positive acute myeloid leukemia with the covalent menin inhibitor BMF-219, icovamenib, 2024, Haematologica
  • Covalent-103: A phase 1, open-label, dose-escalation and expansion study of BMF-500, an oral covalent FLT3 inhibitor, in adults with acute leukemia (AL)., 2024, Journal of Clinical Oncology

Frequently publishing in the Journal of Clinical Oncology, Blood, Cancer Research, Journal of Clinical Investigation, and Haematologica, their body of work demonstrates engagement across multiple high-impact oncology and hematology journals.

Stephan W. Morris has collaborated regularly with coauthors including Thomas W. Butler, Farhad Ravandi, Gary J. Schiller, Uzma Ahmed, and Alexandru Cacovean, reflecting a network of research partnerships primarily in cancer and hematology studies.

Best Publications

  • Fusion of a Kinase Gene, ALK, to a Nucleolar Protein Gene, NPM, in Non-Hodgkin's Lymphoma

    SW Morris;MN Kirstein;MB Valentine;KG Dittmer;KG Dittmer

  • Activating mutations in ALK provide a therapeutic target in neuroblastoma

    Rani E. George;Takaomi Sanda;Megan C. Hanna;Stefan Fröhling

  • Detection of Anaplastic Lymphoma Kinase (ALK) and Nucleolar Protein Nucleophosmin (NPM)-ALK Proteins in Normal and Neoplastic Cells With the Monoclonal Antibody ALK1

    Karen Pulford;Laurence Lamant;Laurence Lamant;Laurence Lamant;Stephan W. Morris;Stephan W. Morris;Stephan W. Morris;Lisa H. Butler;Lisa H. Butler;Lisa H. Butler

  • Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma

    Randy D. Gascoyne;Patricia Aoun;Patricia Aoun;Patricia Aoun;Daniel Wu;Daniel Wu;Daniel Wu;Mukesh Chhanabhai;Mukesh Chhanabhai;Mukesh Chhanabhai

  • ALK , the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

    Stephan W Morris;Clayton Naeve;Prasad Mathew;Payton L James

  • ALK-Positive Lymphoma: A Single Disease With a Broad Spectrum of Morphology

    Daniel Benharroch;Zarouhie Meguerian-Bedoyan;Laurence Lamant;Chauki Amin

  • Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study.

    James Cook;Louis Dehner;Margaret Collins;Zhigui Ma

  • Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.

    Dirk M. Anderson;Satoru Kumaki;Minoo Ahdieh;Jeanette Bertles

  • Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

    D Bischof;K Pulford;D Y Mason;S W Morris

  • Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32).

    Quangeng Zhang;Reiner Siebert;Minhong Yan;Bernd Hinzmann

  • Nucleophosmin–anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway

    Ren Yuan Bai;Tao Ouyang;Tao Ouyang;Cornelius Miething;Cornelius Miething;Stephan W. Morris;Stephan W. Morris

  • A New Subtype of Large B-Cell Lymphoma Expressing the ALK Kinase and Lacking the 2; 5 Translocation

    Georges Delsol;Laurence Lamant;Bernard Mariamé;Karen Pulford

  • The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.

    Hiromitsu Hara;Chitose Ishihara;Arata Takeuchi;Takayuki Imanishi

  • Nucleophosmin-Anaplastic Lymphoma Kinase of Large-Cell Anaplastic Lymphoma Is a Constitutively Active Tyrosine Kinase That Utilizes Phospholipase C-γ To Mediate Its Mitogenicity

    Ren Yuan Bai;Peter Dieter;Christian Peschel;Stephan W. Morris

  • The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1

    Yoneda-Kato N;Look At;Kirstein Mn;Valentine Mb

  • Multilevel Dysregulation of STAT3 Activation in Anaplastic Lymphoma Kinase-Positive T/Null-Cell Lymphoma

    Qian Zhang;Puthryaveett N. Raghunath;Liquan Xue;Miroslaw Majewski

  • Translocations involving anaplastic lymphoma kinase (ALK)

    Justus Duyster;Ren Yuan Bai;Stephan W. Morris

  • Retrovirus-Mediated Gene Transfer of NPM-ALK Causes Lymphoid Malignancy in Mice

    Martin U. Kuefer;A. Thomas Look;Karen Pulford;Frederick G. Behm

  • Fusion of the ALK Gene to the Clathrin Heavy Chain Gene, CLTC, in Inflammatory Myofibroblastic Tumor

    Julia A. Bridge;Masahiko Kanamori;Zhigui Ma;Diane Pickering

  • Anaplastic lymphoma kinase proteins in growth control and cancer.

    K. Pulford;S. W. Morris;Francesco Turturro

Frequent Co-Authors

Christian Peschel
Christian Peschel Technical University of Munich
A. Thomas Look
A. Thomas Look Harvard University
Karen Pulford
Karen Pulford University of Oxford
Marcus B. Valentine
Marcus B. Valentine St. Jude Children's Research Hospital
Demin Wang
Demin Wang Medical College of Wisconsin
Georges Delsol
Georges Delsol Federal University of Toulouse Midi-Pyrénées
David Y. Mason
David Y. Mason John Radcliffe Hospital
Debra J. Gilbert
Debra J. Gilbert National Institutes of Health
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center

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