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Biology and Biochemistry

D-Index
68
Citations
15904
World Ranking
7824
National Ranking
3559

Overview

James M. Hogle is affiliated with Harvard University in the United States. Their research primarily spans fields such as Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions also in Infectious Diseases, Cardiology and Cardiovascular Medicine, Molecular Biology, Epidemiology, and Hepatology.

The scientist's work focuses on topics including Viral Infections and Immunology Research, Viral gastroenteritis research and epidemiology, RNA and protein synthesis mechanisms, Herpesvirus Infections and Treatments, Viral Infectious Diseases and Gene Expression in Insects, Cytomegalovirus and herpesvirus research, and Toxin Mechanisms and Immunotoxins.

James M. Hogle has published extensively in various venues. The most frequent publication sources include PLoS Pathogens, bioRxiv (Cold Spring Harbor Laboratory), mBio, Cell, and Journal of General Virology.

They have collaborated frequently with co-authors such as David J. Filman, Natalie J. Kingston, Joseph S. Snowden, Keith Grehan, and David J. Rowlands.

Recent notable publications by this scientist include the following:

  • "Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate," 2020, PLoS Pathogens
  • "Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance," 2024, Cell
  • "Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate," 2023, Journal of General Virology
  • "Real-Time Imaging of Polioviral RNA Translocation across a Membrane," 2021, mBio
  • "Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers," 2021, mBio

Best Publications

  • Three-Dimensional Structure of Poliovirus at 2.9 Å Resolution

    JM Hogle;M Chow;DJ Filman

  • Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding

    C E Fricks;J M Hogle

  • The crystal structure of Dps, a ferritin homolog that binds and protects DNA.

    R.A. Grant;D.J. Filman;S.E. Finkel;R. Kolter

  • Myristylation of picornavirus capsid protein VP4 and its structural significance.

    M. Chow;J. F. E. Newman;D. Filman;J. M. Hogle

  • Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.

    Henry L. Niman;Richard A. Houghten;Leslie E. Walker;Ralph A. Reisfeld

  • Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus

    D. J. Filman;Rashid Syed;M. Chow;A. J. Macadam

  • Poliovirus Cell Entry: Common Structural Themes in Viral Cell Entry Pathways

    James M. Hogle

  • Imaging Poliovirus Entry in Live Cells

    Boerries Brandenburg;Lily Y Lee;Melike Lakadamyali;Michael J Rust

  • Three-dimensional structure of poliovirus receptor bound to poliovirus.

    David M. Belnap;Brian Michael McDermott;David J. Filman;Naiqian Cheng

  • Three-dimensional structure of poliovirus serotype 1 neutralizing determinants.

    G S Page;A G Mosser;J M Hogle;D J Filman

  • Molecular Tectonic Model of Virus Structural Transitions: the Putative Cell Entry States of Poliovirus

    David M. Belnap;David J. Filman;Benes L. Trus;Naiqian Cheng

  • Poliovirus neutralization by antibodies to internal epitopes of VP4 and VP1 results from reversible exposure of these sequences at physiological temperature.

    Q Li;A G Yafal;Y M Lee;J Hogle

  • Structure and Assembly of Turnip Crinkle Virus. I. X-Ray Crystallographic Structure Analysis at 3.2 A Resolution.

    J.M. Hogle;A. Maeda;S.C. Harrison

  • Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: Structure of the empty capsid assembly intermediate at 2.9 Å resolution

    R. Basavappa;R. Syed;O. Flore;J. P. Icenogle

  • Covalently circularized nanodiscs for studying membrane proteins and viral entry

    Mahmoud L Nasr;Diego Baptista;Mike Strauss;Zhen-Yu J Sun

  • The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.

    Valerie H. Weiss;Anne E. McBride;Michelle A. Soriano;David J. Filman

  • The Crystal Structure of an Unusual Processivity Factor, Herpes Simplex Virus UL42, Bound to the C Terminus of Its Cognate Polymerase

    Harmon J Zuccola;David J Filman;Donald M Coen;James M Hogle

  • The poliovirus 135S particle is infectious.

    S Curry;M Chow;J M Hogle

  • Engineering a poliovirus type 2 antigenic site on a type 1 capsid results in a chimaeric virus which is neurovirulent for mice.

    A. Martin;C. Wychowski;T. Couderc;R. Crainic

  • The Structure of the Poliovirus 135S Cell Entry Intermediate at 10-Angstrom Resolution Reveals the Location of an Externalized Polypeptide That Binds to Membranes

    Doryen Bubeck;David J. Filman;Naiqian Cheng;Alasdair C. Steven

Frequent Co-Authors

Donald M. Coen
Donald M. Coen Harvard University
Martin Karplus
Martin Karplus Harvard University
Naiqian Cheng
Naiqian Cheng National Institutes of Health
Alasdair C. Steven
Alasdair C. Steven National Institutes of Health
Christopher T. Walsh
Christopher T. Walsh Stanford University
Vincent R. Racaniello
Vincent R. Racaniello Columbia University
Gerhard Wagner
Gerhard Wagner Harvard University
Xiaowei Zhuang
Xiaowei Zhuang Harvard University
Stephen Curry
Stephen Curry Imperial College London
George M. Whitesides
George M. Whitesides Harvard University

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