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Biology and Biochemistry

D-Index
113
Citations
38569
World Ranking
873
National Ranking
546

Research.com Recognitions

  • 2009 - Fellow of the Mineralogical Society of America
  • 2008 - Distinguished Scientist Award, Mineralogical Society of America

Overview

Alasdair C. Steven is affiliated with the National Institutes of Health in the United States. Their research spans multiple fields related to biochemistry, genetics, molecular biology, and medicine. The focus areas include molecular biology, ecology, epidemiology, materials chemistry, and structural biology.

The scientist's key research topics cover a diverse array of subjects centered on viral and microbial systems. These topics include bacteriophages and microbial interactions, herpesvirus infections and treatments, advanced electron microscopy techniques and applications, genomics and phylogenetic studies, hepatitis B virus studies, hepatitis C virus research, and cytomegalovirus and herpesvirus research.

Alasdair C. Steven has published in several venues, notably contributing most frequently to OPAL (Open@LaTrobe) at La Trobe University. Other frequent publication venues include Viruses, Structure, eLife, and Nature Communications.

Their recent scientific papers present detailed structural and molecular insights into viruses and related microbial systems. Some notable papers include:

  • Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism (2022, Structure)
  • Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss (2020, eLife)
  • INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication (2021, Nature Communications)
  • The Mottled Capsid of the Salmonella Giant Phage SPN3US, a Likely Maturation Intermediate with a Novel Internal Shell (2020, Viruses)
  • Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae (2020, PLoS Computational Biology)

Throughout their career, Alasdair C. Steven has frequently collaborated with several researchers, including:

  • Weimin Wu
  • Naiqian Cheng
  • Norman R. Watts
  • Paul T. Wingfield
  • Rick Huang

Recognition for Alasdair C. Steven's work includes election as a Fellow of the Mineralogical Society of America in 2009 and receiving the Distinguished Scientist Award from the same society in 2008.

Best Publications

  • Activated STING in a Vascular and Pulmonary Syndrome

    Y. Liu;A.A. Jesus;B. Marrero;D. Yang

  • Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography

    Kay Grünewald;Prashant Desai;Dennis C. Winkler;J. Bernard Heymann;J. Bernard Heymann

  • The molecular biology of intermediate filaments.

    Peter M. Steinert;Alasdair C. Steven;Dennis R. Roop

  • The Sm-like Hfq Protein Increases OxyS RNA Interaction with Target mRNAs

    Aixia Zhang;Karen M Wassarman;Joaquin Ortega;Alasdair C Steven

  • Influenza virus pleiomorphy characterized by cryoelectron tomography.

    Audray Harris;Giovanni Cardone;Dennis C. Winkler;J. Bernard Heymann

  • Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy

    J F Conway;N Cheng;A Zlotnick;P T Wingfield

  • Outcome of the First Electron Microscopy Validation Task Force Meeting

    Richard Henderson;Andrej Sali;Matthew L. Baker;Bridget Carragher

  • Identification of a major keratinocyte cell envelope protein, loricrin.

    Thomas Mehrel;Daniel Hohl;Joseph A. Rothnagel;Mary A. Longley

  • Encapsidated Conformation of Bacteriophage T7 DNA

    Mario E Cerritelli;Naiqian Cheng;Alan H Rosenberg;Catherine E McPherson

  • Arrangement of L2 within the Papillomavirus Capsid

    Christopher B. Buck;Naiqian Cheng;Cynthia D. Thompson;Douglas R. Lowy

  • Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments

    Peter M. Steinert;Robert H. Rice;Dennis R. Roop;Benes L. Trus

  • Homology in Structural Organization BetweenE. coliClpAP Protease and the Eukaryotic 26 S Proteasome

    Martin Kessel;Michael R. Maurizi;Bernard Kim;Eva Kocsis

  • One number does not fit all: Mapping local variations in resolution in cryo-EM reconstructions

    Giovanni Cardone;J. Bernard Heymann;Alasdair C. Steven

  • Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

    Jobin Varkey;Jose Mario Isas;Naoko Mizuno;Martin Borch Jensen

  • Liquid-crystalline, phage-like packing of encapsidated DNA in herpes simplex virus.

    F.P. Booy;W.W. Newcomb;B.L. Trus;J.C. Brown

  • A novel class of herpesvirus with bivalve hosts.

    Andrew J. Davison;Benes L. Trus;Naiqian Cheng;Alasdair C. Steven

  • Protein composition of cornified cell envelopes of epidermal keratinocytes

    Alasdair C. Steven;Peter M. Steinert

  • Structure of the herpes simplex virus capsid : molecular composition of the pentons and the triplexes

    William W. Newcomb;Benes L. Trus;Frank P. Booy;Alasdair C. Steven

  • Dimorphism of Hepatitis B Virus Capsids Is Strongly Influenced by the C-Terminus of the Capsid Protein

    A Zlotnick;N Cheng;J F Conway;F P Booy

  • Lessons from Loricrin-Deficient Mice: Compensatory Mechanisms Maintaining Skin Barrier Function in the Absence of a Major Cornified Envelope Protein

    Peter J. Koch;Pierre A. de Viragh;Pierre A. de Viragh;Elisabeth Scharer;Elisabeth Scharer;Donnie Bundman

Frequent Co-Authors

Naiqian Cheng
Naiqian Cheng National Institutes of Health
Benes L. Trus
Benes L. Trus National Institutes of Health
Paul T. Wingfield
Paul T. Wingfield National Institutes of Health
James F. Conway
James F. Conway University of Pittsburgh
William W. Newcomb
William W. Newcomb National Institutes of Health
Stephen J. Stahl
Stephen J. Stahl National Institutes of Health
Joseph S. Wall
Joseph S. Wall Brookhaven National Laboratory
Michael R. Maurizi
Michael R. Maurizi National Institutes of Health
Peter M. Steinert
Peter M. Steinert National Institutes of Health
Jay C. Brown
Jay C. Brown University of Virginia

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