His scientific interests lie mostly in Cell biology, Molecular biology, Keratin, Epidermis and Keratinocyte. His Cell biology study combines topics in areas such as Genetics, Cellular differentiation, Transcription factor and Immunology. His Molecular biology research incorporates elements of Cell culture, Gene expression, Genetically modified mouse, Transgene and Complementary DNA.
His Keratin research integrates issues from Cell and Keratin 6A, Intermediate filament, Type II keratin, Type I keratin. His studies deal with areas such as Embryonic stem cell and Transforming growth factor, Basal, Internal medicine, Endocrinology as well as Epidermis. He interconnects Downregulation and upregulation, Filaggrin and Notch signaling pathway in the investigation of issues within Keratinocyte.
Dennis R. Roop mainly focuses on Cell biology, Molecular biology, Keratin, Epidermis and Cancer research. Dennis R. Roop has included themes like Loricrin, Transcription factor, Cellular differentiation and Keratinocyte in his Cell biology study. His Molecular biology research is multidisciplinary, incorporating elements of Gene expression, Transgene, RNA, Gene and Regulation of gene expression.
His work deals with themes such as Keratin 6A and Intermediate filament, which intersect with Keratin. His Epidermis study incorporates themes from Embryonic stem cell, Immunology, Hair follicle, Human skin and Gene isoform. Within one scientific family, Dennis R. Roop focuses on topics pertaining to Carcinogenesis under Cancer research, and may sometimes address concerns connected to Genetically modified mouse and Oncogene.
His primary areas of investigation include Cell biology, Cancer research, Epidermis, Hair follicle and Keratinocyte. His biological study spans a wide range of topics, including Corneocyte, Loricrin, Reprogramming, Downregulation and upregulation and Cornified envelope. He focuses mostly in the field of Cancer research, narrowing it down to matters related to Cancer stem cell and, in some cases, Pathology.
Dennis R. Roop combines subjects such as KEAP1 and Human skin with his study of Epidermis. His Keratinocyte course of study focuses on Cellular differentiation and Cell growth. His work deals with themes such as Molecular biology and Laser capture microdissection, which intersect with Melanocyte.
Dennis R. Roop spends much of his time researching Cell biology, Stem cell, Keratinocyte, Cancer research and Epidermis. His Cell biology study integrates concerns from other disciplines, such as Loricrin, Reprogramming, Biochemistry, Downregulation and upregulation and Induced pluripotent stem cell. His Loricrin research incorporates elements of Cornified Envelope Proline-Rich Proteins, Cornified envelope and Keratin.
His research on Keratinocyte often connects related topics like Cellular differentiation. His Cancer research research is multidisciplinary, incorporating elements of Cancer stem cell, Cancer, Side population and Molecular biology. His Molecular biology research includes elements of Tumor progression and Chromosome instability.
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p63 is a p53 homologue required for limb and epidermal morphogenesis.
Alea A. Mills;Binhai Zheng;Xiao-Jing Wang;Hannes Vogel.
Molecular and Cellular Biology of Intermediate Filaments
Peter M. Steinert;Dennis R. Roop.
Annual Review of Biochemistry (1988)
p63 is the molecular switch for initiation of an epithelial stratification program
Maranke I. Koster;Soeun Kim;Alea A. Mills;Francesco J. DeMayo.
Genes & Development (2004)
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
Nobunao Wakabayashi;Ken Itoh;Junko Wakabayashi;Hozumi Motohashi.
Nature Genetics (2003)
Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.
S H Yuspa;A E Kilkenny;P M Steinert;D R Roop.
Journal of Cell Biology (1989)
Multiple defects and perinatal death in mice deficient in follistatin
Martin M. Matzuk;Nalfang Lu;Hannes Vogel;Klaus Sellheyer.
Functional analysis of activins during mammalian development
Martin M. Matzuk;T. Rajendra Kumar;Anne Vassalli;Jackie R. Bickenbach.
The molecular biology of intermediate filaments.
Peter M. Steinert;Alasdair C. Steven;Dennis R. Roop.
Identification of a major keratinocyte cell envelope protein, loricrin.
Thomas Mehrel;Daniel Hohl;Joseph A. Rothnagel;Mary A. Longley.
Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies.
John R. Stanley;Toshihiro Tanaka;Stephan Mueller;Vera Klaus-Kovtun.
Journal of Clinical Investigation (1988)
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