What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Cell biology, Molecular biology, Keratin, Epidermis and Keratinocyte.
His Cell biology study combines topics in areas such as Genetics, Cellular differentiation, Transcription factor and Immunology.
His Molecular biology research incorporates elements of Cell culture, Gene expression, Genetically modified mouse, Transgene and Complementary DNA.
His Keratin research integrates issues from Cell and Keratin 6A, Intermediate filament, Type II keratin, Type I keratin.
His studies deal with areas such as Embryonic stem cell and Transforming growth factor, Basal, Internal medicine, Endocrinology as well as Epidermis.
He interconnects Downregulation and upregulation, Filaggrin and Notch signaling pathway in the investigation of issues within Keratinocyte.
His most cited work include:
- p63 is a p53 homologue required for limb and epidermal morphogenesis. (1733 citations)
- Molecular and Cellular Biology of Intermediate Filaments (1223 citations)
- Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation (631 citations)
What are the main themes of his work throughout his whole career to date?
Dennis R. Roop mainly focuses on Cell biology, Molecular biology, Keratin, Epidermis and Cancer research.
Dennis R. Roop has included themes like Loricrin, Transcription factor, Cellular differentiation and Keratinocyte in his Cell biology study.
His Molecular biology research is multidisciplinary, incorporating elements of Gene expression, Transgene, RNA, Gene and Regulation of gene expression.
His work deals with themes such as Keratin 6A and Intermediate filament, which intersect with Keratin.
His Epidermis study incorporates themes from Embryonic stem cell, Immunology, Hair follicle, Human skin and Gene isoform.
Within one scientific family, Dennis R. Roop focuses on topics pertaining to Carcinogenesis under Cancer research, and may sometimes address concerns connected to Genetically modified mouse and Oncogene.
He most often published in these fields:
- Cell biology (37.47%)
- Molecular biology (32.51%)
- Keratin (25.62%)
What were the highlights of his more recent work (between 2011-2021)?
- Cell biology (37.47%)
- Cancer research (15.98%)
- Epidermis (23.97%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Cancer research, Epidermis, Hair follicle and Keratinocyte.
His biological study spans a wide range of topics, including Corneocyte, Loricrin, Reprogramming, Downregulation and upregulation and Cornified envelope.
He focuses mostly in the field of Cancer research, narrowing it down to matters related to Cancer stem cell and, in some cases, Pathology.
Dennis R. Roop combines subjects such as KEAP1 and Human skin with his study of Epidermis.
His Keratinocyte course of study focuses on Cellular differentiation and Cell growth.
His work deals with themes such as Molecular biology and Laser capture microdissection, which intersect with Melanocyte.
Between 2011 and 2021, his most popular works were:
- ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets (181 citations)
- Nrf2 links epidermal barrier function with antioxidant defense (111 citations)
- XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. (77 citations)
In his most recent research, the most cited papers focused on:
Dennis R. Roop spends much of his time researching Cell biology, Stem cell, Keratinocyte, Cancer research and Epidermis.
His Cell biology study integrates concerns from other disciplines, such as Loricrin, Reprogramming, Biochemistry, Downregulation and upregulation and Induced pluripotent stem cell.
His Loricrin research incorporates elements of Cornified Envelope Proline-Rich Proteins, Cornified envelope and Keratin.
His research on Keratinocyte often connects related topics like Cellular differentiation.
His Cancer research research is multidisciplinary, incorporating elements of Cancer stem cell, Cancer, Side population and Molecular biology.
His Molecular biology research includes elements of Tumor progression and Chromosome instability.
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