Daniel Hohl mainly focuses on Genetics, Keratinocyte, Cell biology, Mutation and Molecular biology. Gene, Missense mutation, Keratin, Ichthyosis and Deubiquitinating Enzyme CYLD are subfields of Genetics in which his conducts study. His work deals with themes such as Notch signaling pathway and Immunology, which intersect with Keratinocyte.
His Cell biology research incorporates elements of Cornified envelope, Epidermis, AIM2 and Biochemistry. The concepts of his Mutation study are interwoven with issues in Stop codon, Hypotrichosis, Phenotype and Haplotype, Genotype. His research integrates issues of Pachyonychia congenita, Pachyonychia, Hair disease and Keratin 17 in his study of Molecular biology.
His primary areas of study are Pathology, Cell biology, Molecular biology, Genetics and Dermatology. Daniel Hohl has included themes like Cornified envelope and Epidermis in his Cell biology study. His Molecular biology study integrates concerns from other disciplines, such as Gene expression, Mutant and Keratinocyte.
His work on Keratinocyte deals in particular with Loricrin and Involucrin. Cancer research and Immunology is closely connected to Epidermis in his research, which is encompassed under the umbrella topic of Loricrin. His study in Mutation, Gene, Keratin, Missense mutation and Genetic heterogeneity is carried out as part of his Genetics studies.
His main research concerns Dermatology, Cancer research, Immunology, Pathology and Cell biology. He interconnects Eccrine naevus and Nevus psiloliparus in the investigation of issues within Dermatology. Daniel Hohl studied Immunology and Disease that intersect with Spondylitis and Ankylosing spondylitis.
His Pathology research is multidisciplinary, incorporating perspectives in Transcriptome and Melanoma. His Cell biology research includes themes of Metaphase and Acetylation. His GLI1 research includes elements of Mutation, Germline mutation and Molecular biology.
Immunology, Cell biology, Cancer research, Human skin and Skin cancer are his primary areas of study. His studies examine the connections between Immunology and genetics, as well as such issues in Disease, with regards to Family history, Prospective cohort study and Atopic dermatitis. Daniel Hohl is involved in the study of Cell biology that focuses on Mitosis in particular.
The study incorporates disciplines such as Protein family, Stem cell, DNA methylation and Keratinocyte in addition to Cancer research. In his study, Daniel Hohl carries out multidisciplinary Keratinocyte and Pentose phosphate pathway research. His Skin cancer study incorporates themes from Peroxisome proliferator-activated receptor delta, Nuclear receptor, Signal transduction and Epidermis.
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Identification of the familial cylindromatosis tumour-suppressor gene.
Graham R. Bignell;William Warren;Sheila Seal;Meiko Takahashi.
Nature Genetics (2000)
Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009
Vinzenz Oji;Gianluca Tadini;Masashi Akiyama;Claudine Blanchet Bardon.
Journal of The American Academy of Dermatology (2010)
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Ilaria Malanchi;Hector Peinado;Deepika Kassen;Thomas Hussenet.
Mutations of keratinocyte transglutaminase in lamellar ichthyosis.
Marcel Huber;Irmingard Rettler;Katja Bernasconi;Edgar Frenk.
The Inflammasome Mediates UVB-Induced Activation and Secretion of Interleukin-1β by Keratinocytes
Laurence Feldmeyer;Martin Keller;Gisela Niklaus;Daniel Hohl.
Current Biology (2007)
Identification of a major keratinocyte cell envelope protein, loricrin.
Thomas Mehrel;Daniel Hohl;Joseph A. Rothnagel;Mary A. Longley.
Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis
Gabriele Richard;Lisa E. Smith;Regina A. Bailey;Peter Itin.
Nature Genetics (1998)
Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis
J. A. Rothnagel;A. M. Dominey;L. D. Dempsey;M. A. Longley.
Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.
D Hohl;T Mehrel;U Lichti;M L Turner.
Journal of Biological Chemistry (1991)
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases
Karine Lefort;Anna Mandinova;Paola Ostano;Vihren Kolev.
Genes & Development (2007)
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