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2025
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Biology and Biochemistry
UK
2026

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Best Female Scientists

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111
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42867
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859
National Ranking
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Biology and Biochemistry

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113
Citations
43137
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Medicine

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Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2009 - Fellow of the Royal Society of Edinburgh

Overview

Irene M. Leigh is a researcher affiliated with the University of Dundee in the United Kingdom. Their work spans multiple fields within biomedical sciences, with a focus on medicine, biochemistry, genetics, and molecular biology. Specifically, their research interests include cell biology, pathology and forensic medicine, and immunology and allergy.

The scientist's research contributions center on topics related to skin and cellular biology, autoimmune bullous skin diseases, and cell adhesion molecules. These areas reflect a specialized engagement with the molecular and cellular mechanisms underlying skin health and disease.

One recent publication authored by Irene M. Leigh is titled "Intracytoplasmic Retention of Type VII Collagen and Dominant Dystrophic Epidermolysis Bullosa: Reversal of Defect Following Cessation of or Marked Improvement in Disease Activity", published in 2021 through UNC Libraries. This paper addresses key issues in cellular retention and disease activity in the context of a genetic skin disorder.

Collaborators frequently working with Irene M. Leigh include:

  • Jo-David Fine
  • Lorraine Johnson
  • Donna J. Cronce
  • J. Timothy Wright
  • Martha L. McCollough

Publications by Irene M. Leigh have appeared in venues such as UNC Libraries.

In recognition of their contributions to scientific research, Irene M. Leigh was awarded the title of Fellow of the Royal Society of Edinburgh in 2009.

Best Publications

  • Connexin 26 mutations in hereditary non-syndromic sensorineural deafness

    Kelsell Dp;Dunlop J;Stevens Hp;Lench Nj

  • Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.

    Tomlinson Ip;Alam Na;Rowan Aj;Barclay E

  • Role of a p53 polymorphism in the development of human papillomavirus-associated cancer.

    Alan Storey;Miranda Thomas;Ann Kalita;Catherine Harwood

  • The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB.

    Jo David Fine;Robin A J Eady;Eugene A. Bauer;Johann W. Bauer

  • Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification

    Jo David Fine;Leena Bruckner-Tuderman;Robin A.J. Eady;Eugene A. Bauer

  • Recessive mutation in desmoplakin disrupts desmoplakin–intermediate filament interactions and causes dilated cardiomyopathy, woolly hair and keratoderma

    Elizabeth E. Norgett;Sarah J. Hatsell;Luis Carvajal-Huerta;Juan-Carlos Ruiz Cabezas

  • Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009

    Vinzenz Oji;Gianluca Tadini;Masashi Akiyama;Claudine Blanchet Bardon

  • Identification of the familial cylindromatosis tumour-suppressor gene.

    Graham R. Bignell;William Warren;Sheila Seal;Meiko Takahashi

  • Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals.

    Catherine A. Harwood;T. Surentheran;Jane M. McGregor;Patricia J. Spink

  • Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.

    Nicholas J. Wang;Zachary Sanborn;Kelly L. Arnett;Laura J. Bayston

  • Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome.

    J. A. McGrath;J. R. McMillan;Carrie S. Shemanko;S. K. Runswick

  • A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering.

    E. B. Lane;E. L. Rugg;H. Navsaria;I. M. Leigh

  • Antibody markers of basal cells in complex epithelia

    P. E. Purkis;J. B. Steel;I. C. Mackenzie;W. B. J. Nathrath

  • Plectin deficiency results in muscular dystrophy with epidermolysis bullosa

    F.J.D. Smith;R.A.J. Eady;I.M. Leigh;J.R. McMillan

  • Keratin 16 and keratin 17 mutations cause pachyonychia congenita.

    W.H.I. McLean;E.L. Rugg;D.P. Lunny;S.M. Morley

  • Human Papillomavirus Infections in Nonmelanoma Skin Cancers From Renal Transplant Recipients and Nonimmunosuppressed Patients

    Vladimir Shamanin;Harald Zur Hausen;Donna Lavergne;Charlotte M. Proby

  • Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.

    David P. Kelsell;Elizabeth E. Norgett;Harriet Unsworth;Muy Teck Teh

  • Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization.

    W. H. I. Mclean;L. Pulkkinen;F. J. D. Smith;E. L. Rugg

  • Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency

    N A Alam;A J Rowan;N C Wortham;P J Pollard

  • Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro.

    I.M. Leigh;H. Navsaria;P.E. Purkis;I.A. Mckay

Frequent Co-Authors

David P. Kelsell
David P. Kelsell Queen Mary University of London
E. B. Lane
E. B. Lane Agency for Science, Technology and Research
John A. McGrath
John A. McGrath King's College London
Robin A.J. Eady
Robin A.J. Eady St Thomas' Hospital
Leena Bruckner-Tuderman
Leena Bruckner-Tuderman University of Freiburg
Fenella Wojnarowska
Fenella Wojnarowska University of Oxford
Edel A. O'Toole
Edel A. O'Toole Queen Mary University of London
Judith Breuer
Judith Breuer University College London
Hiroshi Shimizu
Hiroshi Shimizu Hokkaido University
John K. Field
John K. Field University of Liverpool

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