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Hiroshi Shimizu

Hiroshi Shimizu

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
36552
World Ranking
2651
National Ranking
162

Medicine

D-Index
88
Citations
37027
World Ranking
12968
National Ranking
382

Overview

Hiroshi Shimizu is affiliated with Hokkaido University in Japan and has contributed extensively to research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans 68 publications in Medicine and 32 in Biochemistry, Genetics, and Molecular Biology.

The scientist's subfields of focus include Molecular Biology, Pathology and Forensic Medicine, Cell Biology, Genetics, and Rheumatology. Major research topics associated with their work cover Autoimmune Bullous Skin Diseases, Skin and Cellular Biology Research, Coagulation, Bradykinin, Polyphosphates, and Angioedema, as well as Urticaria and Related Conditions. Additional areas of study include CRISPR and Genetic Engineering, Cellular Mechanics and Interactions, and Wnt/β-catenin signaling in development and cancer.

Hiroshi Shimizu has been published frequently in journals such as The Journal of Dermatology, where they have contributed seven papers. Other common publication venues include the Journal of the European Academy of Dermatology and Venereology (four papers), Journal of Dermatological Science (three papers), Journal of Investigative Dermatology (two papers), and BMC Ophthalmology (two papers).

Frequent collaborators in their academic work include Hideyuki Ujiie, Ken Natsuga, Wataru Nishie, Shota Takashima, and Hiroaki Iwata, reflecting a pattern of joint research efforts across multiple projects.

Representative recent publications by Hiroshi Shimizu include:

  • Granzyme B inhibition reduces disease severity in autoimmune blistering diseases, 2021, Nature Communications
  • Intravenous allogeneic multilineage-differentiating stress-enduring cells in adults with dystrophic epidermolysis bullosa: a phase 1/2 open-label study, 2021, Journal of the European Academy of Dermatology and Venereology
  • Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa, 2020, Journal of Investigative Dermatology
  • A sporadic COVID-19 pneumonia treated with extracorporeal membrane oxygenation in Tokyo, Japan: A case report, 2020, Journal of Infection and Chemotherapy
  • Pseudo-inflammatory manifestations of choroidal lymphoma resembling Vogt-Koyanagi-Harada disease: case report based on multimodal imaging, 2020, BMC Ophthalmology

Best Publications

  • Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type

    Mikako Sasaki;Riichiro Abe;Yasuyuki Fujita;Satomi Ando

  • The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB.

    Jo David Fine;Robin A J Eady;Eugene A. Bauer;Johann W. Bauer

  • Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification

    Jo David Fine;Leena Bruckner-Tuderman;Robin A.J. Eady;Eugene A. Bauer

  • Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009

    Vinzenz Oji;Gianluca Tadini;Masashi Akiyama;Claudine Blanchet Bardon

  • Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

    Dedee F. Murrell;Sarah Dick;A. R. Ahmed;Masayuki Amagai

  • Revised classification system for inherited epidermolysis bullosa: Report of the second international consensus meeting on diagnosis and classification of epidermolysis bullosa

    Jo David Fine;Robin A J Eady;Eugene A. Bauer;Robert A. Briggaman

  • Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer

    Masashi Akiyama;Yoriko Sugiyama-Nakagiri;Kaori Sakai;James R. McMillan

  • Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation

    Ken Inomata;Takahiro Aoto;Takahiro Aoto;Nguyen Thanh Binh;Natsuko Okamoto;Natsuko Okamoto

  • Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts

    Dedee F. Murrell;Benjamin S. Daniel;Pascal Joly;Luca Borradori

  • Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome

    Dawn H. Siegel;Gabrielle H.S. Ashton;Homero G. Penagos;James V. Lee

  • Toxic epidermal necrolysis and Stevens-Johnson syndrome are induced by soluble Fas ligand

    Riichiro Abe;Tadamichi Shimizu;Akihiko Shibaki;Hideki Nakamura

  • Diagnosis and management of pemphigus: Recommendations of an international panel of experts

    Dedee F. Murrell;Sandra Peña;Sandra Peña;Pascal Joly;Branka Marinovic

  • Humanization of autoantigen

    Wataru Nishie;Daisuke Sawamura;Maki Goto;Kei Ito

  • Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis.

    Toshifumi Nomura;Aileen Sandilands;Masashi Akiyama;Haihui Liao

  • Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells

    Shintaro Tanimura;Shintaro Tanimura;Yuko Tadokoro;Ken Inomata;Nguyen Thanh Binh;Nguyen Thanh Binh

  • A randomized double-blind trial of intravenous immunoglobulin for pemphigus

    Masayuki Amagai;Shigaku Ikeda;Hiroshi Shimizu;Hajime Iizuka

  • A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone

    Detlef Zillikens;Detlef Zillikens;Yoshie Kawahara;Akira Ishiko;Hiroshi Shimizu

  • Clinical Severity Correlates with Impaired Barrier in Filaggrin-Related Eczema

    Ikue Nemoto-Hasebe;Masashi Akiyama;Toshifumi Nomura;Aileen Sandilands

  • Human autoantibodies against the 230-kD bullous pemphigoid antigen (BPAG1) bind only to the intracellular domain of the hemidesmosome, whereas those against the 180-kD bullous pemphigoid antigen (BPAG2) bind along the plasma membrane of the hemidesmosome in normal human and swine skin.

    Akira Ishiko;Hiroshi Shimizu;Arata Kikuchi;Tamotsu Ebihara

  • Regulation of Human Melanoma Growth and Metastasis by AGE–AGE Receptor Interactions

    Riichiro Abe;Tadamichi Shimizu;Hiroshi Sugawara;Hirokazu Watanabe

Frequent Co-Authors

Masashi Akiyama
Masashi Akiyama Nagoya University
Riichiro Abe
Riichiro Abe Niigata University
Takeji Nishikawa
Takeji Nishikawa Keio University
Takashi Hashimoto
Takashi Hashimoto Osaka Metropolitan University
John A. McGrath
John A. McGrath King's College London
Jouni Uitto
Jouni Uitto Thomas Jefferson University
Chikara Furusawa
Chikara Furusawa University of Tokyo
Masayuki Amagai
Masayuki Amagai Keio University
Leena Pulkkinen
Leena Pulkkinen University of Eastern Finland
W.H. Irwin McLean
W.H. Irwin McLean University of Dundee

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