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D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
20226
World Ranking
4582
National Ranking
2229

Overview

Pierre A. Coulombe is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. The subfields of study include Cell Biology, Molecular Biology, Immunology, Dermatology, and Urology.

Their work addresses several main topics, such as:

  • Skin and Cellular Biology Research
  • Cellular Mechanics and Interactions
  • Hair Growth and Disorders
  • Dermatological and Skeletal Disorders
  • RNA Research and Splicing
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Nuclear Structure and Function

Recent papers authored or co-authored by Coulombe include:

  • "Regulation of epithelial transitional states in murine and human pulmonary fibrosis," 2023, Journal of Clinical Investigation
  • "Keratin 14-dependent disulfides regulate epidermal homeostasis and barrier function via 14-3-3σ and YAP1," 2020, eLife
  • "Intermediate filaments as effectors of differentiation," 2020, Current Opinion in Cell Biology
  • "Significance of stress keratin expression in normal and diseased epithelia," 2024, iScience
  • "A role for keratin 17 during DNA damage response and tumor initiation," 2021, Proceedings of the National Academy of Sciences

Frequent co-authors in Coulombe's research include:

  • Carole A. Parent
  • Erez Cohen
  • Craig Johnson
  • Raji R. Nair
  • Catherine J. Redmond

Their publications appear regularly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • Current Opinion in Cell Biology
  • eLife
  • Clinical Cancer Research

Best Publications

  • New consensus nomenclature for mammalian keratins

    Jürgen Schweizer;Paul Edward Bowden;Pierre Coulombe;Lutz Langbein

  • ‘Hard’ and ‘soft’ principles defining the structure, function and regulation of keratin intermediate filaments

    Pierre A Coulombe;M.Bishr Omary

  • Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: Genetic and functional analyses

    Pierre A. Coulombe;M. Elizabeth Hutton;Anthony Letal;Adelaide A Hebert

  • Intermediate filament proteins and their associated diseases.

    M Bishr Omary;Pierre A Coulombe;W H Irwin McLean

  • A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth

    Seyun Kim;Pauline Wong;Pierre A. Coulombe

  • Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease.

    Robert Vassar;Pierre A Coulombe;Linda Degenstein;Kathryn Albers

  • Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16.

    Rudolph D. Paladini;Kenzo Takahashi;Nicola S. Bravo;Pierre A. Coulombe

  • Contribution of olfactory neural stem cells to tissue maintenance and regeneration

    Cheuk T Leung;Pierre A Coulombe;Randall R Reed

  • Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds

    Pierre A. Coulombe;Pauline Wong

  • Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm

    Seyun Kim;Pierre A. Coulombe

  • Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development

    Kevin M. McGowan;Pierre A. Coulombe

  • Elucidating the early stages of keratin filament assembly.

    Pierre A. Coulombe;Elaine Fuchs

  • A dysfunctional desmin mutation in a patient with severe generalized myopathy

    Ana M. Muñoz-Mármol;Geraldine Strasser;Marcos Isamat;Pierre A. Coulombe

  • Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.

    Daryle Depianto;Michelle L. Kerns;Andrzej A. Dlugosz;Pierre A. Coulombe

  • A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases.

    P A Coulombe;M E Hutton;R Vassar;E Fuchs

  • Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility

    Pierre A. Coulombe;Michelle L. Kerns;Elaine Fuchs

  • Emerging role for the cytoskeleton as an organizer and regulator of translation

    Seyun Kim;Pierre A. Coulombe

  • Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.

    P A Coulombe;R Kopan;E Fuchs

  • Keratin function in skin epithelia: a broadening palette with surprising shades.

    Li Hong Gu;Pierre A. Coulombe

  • Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis.

    Elaine Fuchs;Ruth A. Esteves;Pierre A. Coulombe

Frequent Co-Authors

Elaine Fuchs
Elaine Fuchs Rockefeller University
Denis Wirtz
Denis Wirtz Johns Hopkins University
M. Bishr Omary
M. Bishr Omary University of Michigan–Ann Arbor
Carole A. Parent
Carole A. Parent University of Michigan–Ann Arbor
Robert Vassar
Robert Vassar Northwestern University
Anthony Letai
Anthony Letai Harvard University
Michael J. Matunis
Michael J. Matunis Johns Hopkins University
David B. Lombard
David B. Lombard University of Michigan–Ann Arbor
J. Michael Walker
J. Michael Walker Indiana University
Kathryn M. Albers
Kathryn M. Albers University of Pittsburgh

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