World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
104
Citations
37218
World Ranking
1261
National Ranking
744

Denis Wirtz publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Denis Wirtz sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 329 publications — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Denis Wirtz D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Denis Wirtz sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 104 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Denis Wirtz is affiliated with Johns Hopkins University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a significant focus on oncology and cell biology.

Their publication record includes a number of recent papers in high-impact journals, reflecting the breadth of their scientific contributions. Notable papers include:

  • 3D genomic mapping reveals multifocality of human pancreatic precancers, 2024, Nature
  • Extracellular vesicles in immunomodulation and tumor progression, 2021, Nature Immunology
  • Single-cell morphology encodes metastatic potential, 2020, Science Advances
  • CODA: quantitative 3D reconstruction of large tissues at cellular resolution, 2022, Nature Methods
  • A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei, 2021, Nature Protocols

Wirtz's research fields of study cover a range within the life sciences, including:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their subfields of study are more specifically focused on:

  • Molecular Biology
  • Oncology
  • Cell Biology
  • Cancer Research
  • Biophysics

Their main topics of work demonstrate a strong emphasis on cancer research and cellular analysis techniques. These topics include:

  • Pancreatic and Hepatic Oncology Research
  • Single-cell and spatial transcriptomics
  • Cellular Mechanics and Interactions
  • Cancer Genomics and Diagnostics
  • Cell Image Analysis Techniques
  • Cancer Cells and Metastasis
  • AI in cancer detection

Frequent co-authors in their collaborative research include:

  • Ashley Kiemen
  • Pei-Hsun Wu
  • Laura D. Wood
  • André Forjaz

Wirtz has published extensively in various scientific venues, with the highest number of publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Science Advances
  • Nature Methods
  • Cell Systems

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • The physics of cancer: the role of physical interactions and mechanical forces in metastasis

    Denis Wirtz;Konstantinos Konstantopoulos;Peter C. Searson

  • Hypoxia and the extracellular matrix: drivers of tumour metastasis

    Daniele M. Gilkes;Gregg L. Semenza;Denis Wirtz

  • Reversible Hydrogels from Self-Assembling Artificial Proteins

    Wendy A. Petka;James L. Harden;Kevin P. McGrath;Denis Wirtz

  • Micro- and macrorheology of mucus.

    Samuel K. Lai;Ying Ying Wang;Denis Wirtz;Justin Hanes

  • Particle Tracking Microrheology of Complex Fluids

    T. G. Mason;K. Ganesan;J. H. van Zanten;D. Wirtz

  • Particle-Tracking Microrheology of Living Cells: Principles and Applications

    Denis Wirtz

  • A distinctive role for focal adhesion proteins in three-dimensional cell motility

    Stephanie I. Fraley;Yunfeng Feng;Yunfeng Feng;Ranjini Krishnamurthy;Dong Hwee Kim

  • Mechanics of Living Cells Measured by Laser Tracking Microrheology

    Soichiro Yamada;Denis Wirtz;Scot C. Kuo

  • A perinuclear actin cap regulates nuclear shape

    Shyam B. Khatau;Christopher M. Hale;P. J. Stewart-Hutchinson;Meet S. Patel

  • A comparison of methods to assess cell mechanical properties.

    Pei Hsun Wu;Dikla Raz Ben Aroush;Atef Asnacios;Wei Chiang Chen

  • Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

    Kimberly M. Stroka;Hongyuan Jiang;Shih Hsun Chen;Ziqiu Tong

  • Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts

    Daniele M. Gilkes;Saumendra Bajpai;Pallavi Chaturvedi;Denis Wirtz

  • Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

    Carmen Chak Lui Wong;Daniele M. Gilkes;Huafeng Zhang;Huafeng Zhang;Jasper Chen

  • Efficient active transport of gene nanocarriers to the cell nucleus

    Junghae Suh;Denis Wirtz;Justin Hanes

  • Micromechanical Mapping of Live Cells by Multiple-Particle-Tracking Microrheology

    Yiider Tseng;Thomas P. Kole;Denis Wirtz

  • Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes

    Amit Agarwal;Pei Hsun Wu;Ethan G. Hughes;Masahiro Fukaya

  • Focal adhesion size uniquely predicts cell migration

    Dong Hwee Kim;Denis Wirtz

  • Enhanced Viscoelasticity of Human Cystic Fibrotic Sputum Correlates with Increasing Microheterogeneity in Particle Transport

    Michelle Dawson;Denis Wirtz;Justin Hanes

  • Extracellular vesicles in immunomodulation and tumor progression.

    Carolyn Marar;Carolyn Marar;Bartholomew Starich;Denis Wirtz

  • Three-dimensional cell migration does not follow a random walk

    Pei Hsun Wu;Anjil Giri;Sean X. Sun;Denis Wirtz;Denis Wirtz

Frequent Co-Authors

Daniele M. Gilkes
Daniele M. Gilkes Johns Hopkins University
Konstantinos Konstantopoulos
Konstantinos Konstantopoulos Johns Hopkins University
Gregory D. Longmore
Gregory D. Longmore Washington University in St. Louis
Peter C. Searson
Peter C. Searson Johns Hopkins University
Justin Hanes
Justin Hanes Johns Hopkins University
Gregg L. Semenza
Gregg L. Semenza Johns Hopkins University School of Medicine
Tian Li Wang
Tian Li Wang Johns Hopkins University
Benjamin W. Schafer
Benjamin W. Schafer Johns Hopkins University
Ie Ming Shih
Ie Ming Shih Johns Hopkins University
Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine

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