D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 81 Citations 20,418 202 World Ranking 1627 National Ranking 940

Research.com Recognitions

Awards & Achievements

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Denis Wirtz mainly investigates Cell biology, Cytoskeleton, Actin, Biophysics and Microrheology. His Cell biology research includes themes of Cell and Cell adhesion. The Cytoskeleton study combines topics in areas such as Mechanics, Nuclear protein, Microtubule and Effector.

His Actin research incorporates themes from Protein filament, Actin remodeling and Myosin. His study looks at the intersection of Biophysics and topics like Analytical chemistry with Diffusion, Nanoparticle and Microviscosity. His study in Microrheology is interdisciplinary in nature, drawing from both Diffusing-wave spectroscopy and Optics, Microscopy.

His most cited work include:

  • Reversible Hydrogels from Self-Assembling Artificial Proteins (844 citations)
  • The physics of cancer: the role of physical interactions and mechanical forces in metastasis (743 citations)
  • Micro- and macrorheology of mucus. (654 citations)

What are the main themes of his work throughout his whole career to date?

Denis Wirtz focuses on Cell biology, Biophysics, Cytoskeleton, Actin and Cell. His studies deal with areas such as Cell migration and Cell adhesion as well as Cell biology. Denis Wirtz focuses mostly in the field of Cell migration, narrowing it down to matters related to Extracellular matrix and, in some cases, Cancer cell, Cancer research and Breast cancer.

His research integrates issues of Adhesion, Nanotechnology, Force spectroscopy and Microrheology, Viscoelasticity in his study of Biophysics. His research in Cytoskeleton tackles topics such as Nuclear lamina which are related to areas like Lamin and Cell nucleus. His Actin research is multidisciplinary, relying on both Actin cytoskeleton, Actin remodeling, Nucleus, Protein filament and Microtubule.

He most often published in these fields:

  • Cell biology (47.52%)
  • Biophysics (30.61%)
  • Cytoskeleton (20.70%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (47.52%)
  • Cell (16.91%)
  • Cancer research (12.24%)

In recent papers he was focusing on the following fields of study:

Denis Wirtz mostly deals with Cell biology, Cell, Cancer research, Cancer and Biophysics. His Cell biology research incorporates elements of CD44 and Cell division. His research related to Cytoskeleton and Cell migration might be considered part of Cell.

The concepts of his Cytoskeleton study are interwoven with issues in Cytoplasm, Intracellular and Actin. His Cancer research research is multidisciplinary, relying on both Cancer cell, Carcinogenesis, Metastasis, Cell cycle and Breast cancer. Denis Wirtz is involved in the study of Biophysics that focuses on Myosin in particular.

Between 2015 and 2021, his most popular works were:

  • A comparison of methods to assess cell mechanical properties. (180 citations)
  • Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes (171 citations)
  • Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion (88 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Biophysics, Cell biology, Signal transduction, Cancer research and Cell culture are his primary areas of study. His study explores the link between Biophysics and topics such as Cell adhesion that cross with problems in Cytometry, Rheometry, Viscosity, Microrheology and Rheology. His Cell biology research includes elements of Cytoskeleton and Cell fate determination.

His Signal transduction research is multidisciplinary, incorporating elements of Mechanotransduction, Cell migration and Cell growth. His Cancer research study also includes fields such as

  • Metastasis that intertwine with fields like Extracellular matrix,
  • Cell cycle that intertwine with fields like Histone, DNA repair, Molecular biology and Chromatin. As a part of the same scientific family, Denis Wirtz mostly works in the field of Actin, focusing on Lamin and, on occasion, Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Reversible Hydrogels from Self-Assembling Artificial Proteins

Wendy A. Petka;James L. Harden;Kevin P. McGrath;Denis Wirtz.
Science (1998)

1243 Citations

The physics of cancer: the role of physical interactions and mechanical forces in metastasis

Denis Wirtz;Konstantinos Konstantopoulos;Peter C. Searson.
Nature Reviews Cancer (2011)

913 Citations

Particle Tracking Microrheology of Complex Fluids

T. G. Mason;K. Ganesan;J. H. van Zanten;D. Wirtz.
Physical Review Letters (1997)

876 Citations

Micro- and macrorheology of mucus.

Samuel K. Lai;Ying Ying Wang;Denis Wirtz;Justin Hanes.
Advanced Drug Delivery Reviews (2009)

874 Citations

Hypoxia and the extracellular matrix: drivers of tumour metastasis

Daniele M. Gilkes;Gregg L. Semenza;Denis Wirtz.
Nature Reviews Cancer (2014)

839 Citations

Mechanics of Living Cells Measured by Laser Tracking Microrheology

Soichiro Yamada;Denis Wirtz;Scot C. Kuo.
Biophysical Journal (2000)

591 Citations

Particle-Tracking Microrheology of Living Cells: Principles and Applications

Denis Wirtz.
Annual Review of Biophysics (2009)

589 Citations

A distinctive role for focal adhesion proteins in three-dimensional cell motility

Stephanie I. Fraley;Yunfeng Feng;Yunfeng Feng;Ranjini Krishnamurthy;Dong Hwee Kim.
Nature Cell Biology (2010)

584 Citations

Efficient active transport of gene nanocarriers to the cell nucleus

Junghae Suh;Denis Wirtz;Justin Hanes.
Proceedings of the National Academy of Sciences of the United States of America (2003)

469 Citations

A perinuclear actin cap regulates nuclear shape

Shyam B. Khatau;Christopher M. Hale;P. J. Stewart-Hutchinson;Meet S. Patel.
Proceedings of the National Academy of Sciences of the United States of America (2009)

465 Citations

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