What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Internal medicine
His scientific interests lie mostly in Cell biology, Transcription factor, Molecular biology, Hypoxia and Vascular endothelial growth factor.
His Cell biology study combines topics from a wide range of disciplines, such as Protein subunit, Biochemistry and Oxygen homeostasis.
His research in Transcription factor is mostly focused on Hypoxia-Inducible Factor 1.
His Hypoxia study integrates concerns from other disciplines, such as Erythropoietin, Pharmacology and Ischemia.
The study incorporates disciplines such as Tumor progression and Angiogenesis, HIF1A in addition to Vascular endothelial growth factor.
His biological study spans a wide range of topics, including Cancer, Hypoxia-inducible factors and Pathology.
His most cited work include:
- Targeting HIF-1 for cancer therapy (4879 citations)
- Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension (4775 citations)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cancer research, Hypoxia, Cell biology, Internal medicine and Endocrinology.
His Cancer research research includes themes of Cancer cell, Cancer, Metastasis and Hypoxia-inducible factors.
The Hypoxia study combines topics in areas such as Cell, Pulmonary hypertension, Immunology, Ischemia and Pharmacology.
His Cell biology research is multidisciplinary, incorporating perspectives in Hypoxia-Inducible Factor 1, Transcription factor, Oxygen homeostasis and Biochemistry.
His Hypoxia-Inducible Factor 1 study incorporates themes from Signal transduction and Transcription.
Regulation of gene expression and Enhancer is closely connected to Molecular biology in his research, which is encompassed under the umbrella topic of Transcription factor.
He most often published in these fields:
- Cancer research (27.68%)
- Hypoxia (25.61%)
- Cell biology (25.80%)
What were the highlights of his more recent work (between 2013-2021)?
- Cancer research (27.68%)
- Hypoxia-inducible factors (16.20%)
- Internal medicine (22.98%)
In recent papers he was focusing on the following fields of study:
Gregg L. Semenza spends much of his time researching Cancer research, Hypoxia-inducible factors, Internal medicine, Cell biology and Metastasis.
His research in Cancer research intersects with topics in Cancer, Cancer cell, Cancer stem cell, Stem cell and Breast cancer.
The concepts of his Hypoxia-inducible factors study are interwoven with issues in Oxidative stress, Cell, Angiogenesis, Pathology and Transcription.
His Internal medicine research includes elements of Endocrinology, Retinal and Oncology.
His Cell biology research incorporates elements of Regulation of gene expression, Biochemistry, Metabolism and Oxygen homeostasis.
Many of his studies on Hypoxia involve topics that are commonly interrelated, such as Signal transduction.
Between 2013 and 2021, his most popular works were:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Hypoxia and the extracellular matrix: drivers of tumour metastasis (604 citations)
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA (422 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cancer
- Internal medicine
His main research concerns Cancer research, Hypoxia-inducible factors, Metastasis, Cell biology and Cancer cell.
Gregg L. Semenza is interested in Angiogenesis, which is a field of Cancer research.
His Hypoxia-inducible factors research is multidisciplinary, relying on both Cancer and Pathogenesis.
His Metastasis research is multidisciplinary, incorporating elements of Pathology, Extracellular matrix, Stem cell and Doxorubicin.
Gregg L. Semenza combines subjects such as Hypoxia, CDC2 Protein Kinase and Minichromosome maintenance with his study of Cell biology.
His work deals with themes such as Hypoxia-Inducible Factor 1 and Oncology, which intersect with Internal medicine.
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