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William G. Kaelin

William G. Kaelin

Harvard University
United States

Award Badge
Biology and Biochemistry
USA
2023

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Medicine 149 1192 1099 687 621 347 92564
Biology and Biochemistry 149 187 165 129 114 346 92186

William G. Kaelin publications per year

The chart shows the history of publications by William G. Kaelin between 1952 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. William G. Kaelin published across 74 years, from 1952 to 2025, averaging 6.3 papers a year. Output peaked at 70 publications in 2023. 45 of the 466 publications appeared in the last two years.

No. of publications
20 40 60
Bar chart. Horizontal axis: year, 1952 to 2025. Vertical axis: number of publications, 0 to 70. Peak 70 publications in 2023. 1952: 1 publication 1953: 0 publications 1954: 1 publication 1955: 0 publications 1956: 0 publications 1957: 0 publications 1958: 0 publications 1959: 0 publications 1960: 0 publications 1961: 0 publications 1962: 0 publications 1963: 0 publications 1964: 0 publications 1965: 0 publications 1966: 0 publications 1967: 0 publications 1968: 0 publications 1969: 0 publications 1970: 0 publications 1971: 0 publications 1972: 0 publications 1973: 0 publications 1974: 0 publications 1975: 0 publications 1976: 0 publications 1977: 0 publications 1978: 0 publications 1979: 0 publications 1980: 0 publications 1981: 0 publications 1982: 1 publication 1983: 1 publication 1984: 1 publication 1985: 0 publications 1986: 1 publication 1987: 0 publications 1988: 0 publications 1989: 0 publications 1990: 1 publication 1991: 4 publications 1992: 4 publications 1993: 6 publications 1994: 4 publications 1995: 5 publications 1996: 10 publications 1997: 11 publications 1998: 13 publications 1999: 21 publications 2000: 11 publications 2001: 11 publications 2002: 24 publications 2003: 16 publications 2004: 16 publications 2005: 14 publications 2006: 7 publications 2007: 13 publications 2008: 11 publications 2009: 14 publications 2010: 10 publications 2011: 13 publications 2012: 9 publications 2013: 8 publications 2014: 14 publications 2015: 8 publications 2016: 13 publications 2017: 10 publications 2018: 7 publications 2019: 12 publications 2020: 6 publications 2021: 12 publications 2022: 7 publications 2023: 70 publications 2024: 6 publications 2025: 39 publications
1952 2025

466 publications in total across all disciplines

View publications per year as a table
William G. Kaelin: publications per year, 1952 to 2025
Year Publications
1952 1
1953 0
1954 1
1955 0
1956 0
1957 0
1958 0
1959 0
1960 0
1961 0
1962 0
1963 0
1964 0
1965 0
1966 0
1967 0
1968 0
1969 0
1970 0
1971 0
1972 0
1973 0
1974 0
1975 0
1976 0
1977 0
1978 0
1979 0
1980 0
1981 0
1982 1
1983 1
1984 1
1985 0
1986 1
1987 0
1988 0
1989 0
1990 1
1991 4
1992 4
1993 6
1994 4
1995 5
1996 10
1997 11
1998 13
1999 21
2000 11
2001 11
2002 24
2003 16
2004 16
2005 14
2006 7
2007 13
2008 11
2009 14
2010 10
2011 13
2012 9
2013 8
2014 14
2015 8
2016 13
2017 10
2018 7
2019 12
2020 6
2021 12
2022 7
2023 70
2024 6
2025 39
Total 466
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William G. Kaelin publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where William G. Kaelin sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 100 bars. Horizontal axis: publications, 47–56 to 1,028+. Vertical axis: number of scientists, 0 to 980. Most scientists, 980, have 127–136 publications. The last bar groups every scientist with 1,028 publications or more. The highlighted bar, 337–346 publications, is where this scientist sits. 47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientist 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientist 1,028+ publications: 100 scientists
47–56 publications 1,028+

This scientist: 346 publications — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

View publications distribution as a table
Number of Biology and Biochemistry scientists by publication count, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
Publications Scientists This scientist
47–56 8
57–66 35
67–76 106
77–86 231
87–96 413
97–106 546
107–116 704
117–126 848
127–136 980
137–146 942
147–156 969
157–166 949
167–176 951
177–186 915
187–196 787
197–206 840
207–216 733
217–226 708
227–236 651
237–246 605
247–256 510
257–266 524
267–276 434
277–286 417
287–296 350
297–306 363
307–316 315
317–326 296
327–336 261
337–346 240 346
347–356 219
357–366 196
367–376 154
377–386 161
387–396 155
397–406 145
407–416 124
417–426 112
427–436 132
437–446 116
447–456 99
457–466 81
467–476 91
477–486 80
487–496 80
497–506 59
507–516 36
517–526 46
527–536 54
537–546 44
547–556 43
557–566 43
567–576 42
577–586 25
587–596 34
597–606 23
607–616 33
617–626 31
627–636 27
637–646 25
647–656 28
657–666 34
667–676 18
677–686 16
687–696 10
697–706 12
707–716 21
717–726 12
727–736 12
737–746 10
747–756 7
757–766 13
767–776 15
777–786 13
787–796 9
797–806 9
807–816 7
817–826 4
827–836 9
837–846 7
847–856 3
857–866 5
867–876 5
877–886 11
887–896 3
897–906 4
907–916 7
917–926 5
927–936 6
937–946 6
947–956 3
957–966 7
967–976 2
977–986 2
987–996 1
997–1,006 5
1,007–1,016 2
1,017–1,026 2
1,027 1
1,028+ 100
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William G. Kaelin D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where William G. Kaelin sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 65 bars. Horizontal axis: D-Index, 40–41 to 167+. Vertical axis: number of scientists, 0 to 1,253. Most scientists, 1,253, have 58–59 D-Index. The last bar groups every scientist with 167 D-Index or more. The highlighted bar, 148–149 D-Index, is where this scientist sits. 40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40–41 D-Index 167+

This scientist: 149 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

View D-Index distribution as a table
Number of Biology and Biochemistry scientists by D-index, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
D-Index Scientists This scientist
40–41 80
42–43 183
44–45 316
46–47 504
48–49 718
50–51 899
52–53 1,025
54–55 1,149
56–57 1,235
58–59 1,253
60–61 1,162
62–63 1,130
64–65 1,031
66–67 897
68–69 814
70–71 714
72–73 709
74–75 596
76–77 512
78–79 473
80–81 412
82–83 373
84–85 358
86–87 285
88–89 273
90–91 227
92–93 208
94–95 193
96–97 153
98–99 157
100–101 148
102–103 120
104–105 113
106–107 100
108–109 86
110–111 67
112–113 71
114–115 73
116–117 64
118–119 53
120–121 60
122–123 54
124–125 43
126–127 38
128–129 49
130–131 26
132–133 18
134–135 23
136–137 32
138–139 32
140–141 27
142–143 19
144–145 22
146–147 12
148–149 16 149
150–151 14
152–153 10
154–155 13
156–157 10
158–159 7
160–161 9
162–163 13
164–165 4
166 4
167+ 98
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Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2020 - Fellow of the American Academy of Arts and Sciences

Overview

William G. Kaelin is affiliated with Harvard University in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Within these areas, their subfields of focus include Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, Genetics, and Immunology.

The main topics covered in their work include:

  • Cancer, Hypoxia, and Metabolism
  • Renal cell carcinoma treatment
  • Glioma Diagnosis and Treatment
  • Renal and related cancers
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Biochemical and Molecular Research

William G. Kaelin's recent publications demonstrate engagement with cancer biology and molecular mechanisms associated with oxygen sensing and metabolic pathways. Selected recent papers include:

  • "Targeting the HIF2-VEGF axis in renal cell carcinoma," 2020, Nature Medicine
  • "2-Oxoglutarate-dependent dioxygenases in cancer," 2020, Nature Reviews. Cancer
  • "Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions," 2022, Neuro-Oncology
  • "Von Hippel-Lindau disease: insights into oxygen sensing, protein degradation, and cancer," 2022, Journal of Clinical Investigation
  • "De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma," 2022, Cancer Cell

Frequent co-authors collaborated with include Sabina Signoretti, Samuel K. McBrayer, Diana D. Shi, Toni K. Choueiri, and Nitin H. Shirole.

The venues where William G. Kaelin frequently publishes encompass UNC Libraries, Neuro-Oncology, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, and Nature Medicine.

Among the recognitions awarded, William G. Kaelin was named Fellow of the American Academy of Arts and Sciences in 2020.

Best Publications

  • HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing

    Mircea Ivan;Keiichi Kondo;Haifeng Yang;William Y. Kim

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler

  • Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

    William G. Kaelin;Peter J. Ratcliffe

  • Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein

    Michael Ohh;Cheol Won Park;Cheol Won Park;Mircea Ivan;Michael A. Hoffman

  • The Concept of Synthetic Lethality in the Context of Anticancer Therapy

    William G. Kaelin

  • Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

    James Brugarolas;Kui Lei;Rebecca L. Hurley;Brendan D. Manning

  • The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins

    Gang Lu;Richard E. Middleton;Huahang Sun;MarkVic Naniong

  • p73 is a human p53-related protein that can induce apoptosis

    Christine A. Jost;Maria C. Marin;William G. Kaelin

  • Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

    Diana Miao;Diana Miao;Claire A. Margolis;Claire A. Margolis;Wenhua Gao;Martin H. Voss;Martin H. Voss

  • Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function.

    Charles E. Stebbins;William G. Kaelin;Nikola P. Pavletich

  • Role of VHL Gene Mutation in Human Cancer

    William Y. Kim;William G. Kaelin

  • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

    JianGen Gong;Antonio Costanzo;Hong-Qiong Yang;Gerry Melino

  • Molecular basis of the VHL hereditary cancer syndrome

    William G. Kaelin

  • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.

    Xiao Qiang Qin;David M. Livingston;William G. Kaelin;Peter D. Adams

  • Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

    William G. Kaelin;Wilhelm Krek;William R. Sellers;James A. DeCaprio

  • Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

    Othon Iliopoulos;Andrew P. Levy;Chian Jiang;William G. Kaelin

  • Influence of Metabolism on Epigenetics and Disease

    William G. Kaelin;Steven L. McKnight

  • E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation

    Seth J Field;Seth J Field;Fong-Ying Tsai;Fong-Ying Tsai;Frank Kuo;Ana M Zubiaga;Ana M Zubiaga

  • Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.

    T. Kamura;D. M. Koepp;D. M. Koepp;M. N. Conrad;D. Skowyra

  • Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling

    Jung-Hyun Min;Haifeng Yang;Mircea Ivan;Frank Gertler

Frequent Co-Authors

Sabina Signoretti
Sabina Signoretti Brigham and Women's Hospital
David M. Livingston
David M. Livingston Harvard University
William R. Sellers
William R. Sellers Harvard University
Javid Moslehi
Javid Moslehi University of California, San Francisco
Qin Yan
Qin Yan Yale University
Michael Ohh
Michael Ohh University of Toronto
Wenyi Wei
Wenyi Wei Beth Israel Deaconess Medical Center
Rameen Beroukhim
Rameen Beroukhim Harvard University
Matthew Meyerson
Matthew Meyerson Harvard University
Qing Zhang
Qing Zhang Nanyang Technological University

External Links

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Publications: 180

Gregg L. Semenza

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Publications: 159

Christopher J. Schofield

Christopher J. Schofield

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Publications: 144

W. Marston Linehan

W. Marston Linehan

National Institutes of Health

Publications: 136

M. Celeste Simon

M. Celeste Simon

University of Pennsylvania

Publications: 125

Toni K. Choueiri

Toni K. Choueiri

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Publications: 114

Gerry Melino

Gerry Melino

University of Rome Tor Vergata

Publications: 106

Patrick H. Maxwell

Patrick H. Maxwell

University of Cambridge

Publications: 95

Eamonn R. Maher

Eamonn R. Maher

University of Cambridge

Publications: 95

adrian l harris

adrian l harris

University of Oxford

Publications: 90

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W. Kimryn Rathmell

Vanderbilt University Medical Center

Publications: 90

Wenyi Wei

Wenyi Wei

Beth Israel Deaconess Medical Center

Publications: 89

Amato J. Giaccia

Amato J. Giaccia

Stanford University

Publications: 88

Karel Pacak

Karel Pacak

National Institutes of Health

Publications: 82

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Brigham and Women's Hospital

Publications: 80

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University of Cambridge

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