Wenyi Wei

Overview

Best Publications

• Bypass of Senescence After Disruption of p21CIP1/WAF1 Gene in Normal Diploid Human Fibroblasts

  Jeremy P. Brown;Wenyi Wei;John M. Sedivy

  1079
  Citations

• Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

  Jinfang Zhang;Xia Bu;Haizhen Wang;Yasheng Zhu

  831
  Citations

• Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

  Christopher M. Counter;William C. Hahn;Wenyi Wei;Stephanie Dickinson Caddle

  825
  Citations

• SCF FBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

  Hiroyuki Inuzuka;Shavali Shaik;Ichiro Onoyama;Darning Gao

  683
  Citations

• Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer.

  Sungwoo Lee;Eijiro Nakamura;Haifeng Yang;Wenyi Wei

  656
  Citations

• Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

  Wenyi Wei;Nagi G. Ayad;Yong Wan;Guo Jun Zhang

  585
  Citations

• Roles of F-box proteins in cancer

  Zhiwei Wang;Pengda Liu;Hiroyuki Inuzuka;Wenyi Wei

  498
  Citations

• The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.

  Wenyi Wei;Jianping Jin;Susanne Schlisio;Susanne Schlisio;J. Wade Harper

  489
  Citations

• The role of ubiquitination in tumorigenesis and targeted drug discovery

  Lu Deng;Tong Meng;Lei Chen;Wenyi Wei

  471
  Citations

• The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

  Chia Hsin Chan;Chien Feng Li;Chien Feng Li;Wei Lei Yang;Wei Lei Yang;Yuan Gao;Yuan Gao

  422
  Citations

• Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

  Pengda Liu;Michael Begley;Wojciech Michowski;Hiroyuki Inuzuka

  406
  Citations

• PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex

  Pengda Liu;Wenjian Gan;Y. Rebecca Chin;Kohei Ogura

  387
  Citations

• Role of p21 in Apoptosis and Senescence of Human Colon Cancer Cells Treated with Camptothecin

  Zhiyong Han;Wenyi Wei;Stephen Dunaway;Stephen Dunaway;James W. Darnowski

  327
  Citations

• Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.

  Antonella Papa;Lixin Wan;Massimo Bonora;Leonardo Salmena

  303
  Citations

• Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

  Daming Gao;Hiroyuki Inuzuka;Alan Tseng;Rebecca Y. Chin

  297
  Citations

• Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

  Pengda Liu;Wenjian Gan;Hiroyuki Inuzuka;Adam S. Lazorchak

  286
  Citations

• Role of p14(ARF) in replicative and induced senescence of human fibroblasts.

  Wenyi Wei;Ruth M. Hemmer;John M. Sedivy

  286
  Citations

• Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

  Xiangpeng Dai;Wenjian Gan;Xiaoning Li;Xiaoning Li;Shangqian Wang

  272
  Citations

• mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

  Daming Gao;Hiroyuki Inuzuka;Meng Kwang Marcus Tan;Hidefumi Fukushima

  265
  Citations

• Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

  Zeping Wang;Nandini Bhattacharya;Philip F Mixter;Wenyi Wei

  264
  Citations