SCF FBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Hiroyuki Inuzuka;Shavali Shaik;Ichiro Onoyama;Darning Gao.
Nature (2011)
Roles of F-box proteins in cancer
Zhiwei Wang;Pengda Liu;Hiroyuki Inuzuka;Wenyi Wei.
Nature Reviews Cancer (2014)
STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase
Hiroshi Tokumitsu;Hiroyuki Inuzuka;Yumi Ishikawa;Masahiko Ikeda.
Journal of Biological Chemistry (2002)
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
Pengda Liu;Michael Begley;Wojciech Michowski;Hiroyuki Inuzuka.
Nature (2014)
R-cadherin: A novel Ca2+-dependent cell-cell adhesion molecule expressed in the retina
Hiroyuki Inuzuka;Seiji Miyatani;Masatoshi Takeichi.
Neuron (1991)
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
Daming Gao;Hiroyuki Inuzuka;Alan Tseng;Rebecca Y. Chin.
Nature Cell Biology (2009)
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis
Pengda Liu;Wenjian Gan;Hiroyuki Inuzuka;Adam S. Lazorchak.
Nature Cell Biology (2013)
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Daming Gao;Hiroyuki Inuzuka;Meng Kwang Marcus Tan;Hidefumi Fukushima.
Molecular Cell (2011)
Phosphorylation by Casein Kinase I promotes the turnover of the Mdm2 oncoprotein via the SCFβ-TRCP ubiquitin ligase
Hiroyuki Inuzuka;Alan Tseng;Daming Gao;Bo Zhai.
Cancer Cell (2010)
Acetylation-Dependent Regulation of Skp2 Function
Hiroyuki Inuzuka;Daming Gao;Lydia W.S. Finley;Wen Yang.
Cell (2012)
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Beth Israel Deaconess Medical Center
Tohoku University
Beth Israel Deaconess Medical Center
Okayama University
Harvard University
Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center
Harvard University
Wayne State University
RIKEN
Stellenbosch University
University of Salento
Hunan University
University of California, Davis
University of California, San Diego
National University of Singapore
Princess Margaret Cancer Centre
University of California, San Francisco
Near East University
Oregon National Primate Research Center
Robert Koch Institute
French Research Institute for Exploitation of the Sea
Dagestan Scientific Center of the Russian Academy of Sciences
Chinese Academy of Sciences
University of Warsaw
University of Cincinnati