SCF FBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Hiroyuki Inuzuka;Shavali Shaik;Ichiro Onoyama;Darning Gao.
Roles of F-box proteins in cancer
Zhiwei Wang;Pengda Liu;Hiroyuki Inuzuka;Wenyi Wei.
Nature Reviews Cancer (2014)
STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase
Hiroshi Tokumitsu;Hiroyuki Inuzuka;Yumi Ishikawa;Masahiko Ikeda.
Journal of Biological Chemistry (2002)
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
Pengda Liu;Michael Begley;Wojciech Michowski;Hiroyuki Inuzuka.
R-cadherin: A novel Ca2+-dependent cell-cell adhesion molecule expressed in the retina
Hiroyuki Inuzuka;Seiji Miyatani;Masatoshi Takeichi.
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
Daming Gao;Hiroyuki Inuzuka;Alan Tseng;Rebecca Y. Chin.
Nature Cell Biology (2009)
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis
Pengda Liu;Wenjian Gan;Hiroyuki Inuzuka;Adam S. Lazorchak.
Nature Cell Biology (2013)
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Daming Gao;Hiroyuki Inuzuka;Meng Kwang Marcus Tan;Hidefumi Fukushima.
Molecular Cell (2011)
Phosphorylation by Casein Kinase I promotes the turnover of the Mdm2 oncoprotein via the SCFβ-TRCP ubiquitin ligase
Hiroyuki Inuzuka;Alan Tseng;Daming Gao;Bo Zhai.
Cancer Cell (2010)
Acetylation-Dependent Regulation of Skp2 Function
Hiroyuki Inuzuka;Daming Gao;Lydia W.S. Finley;Wen Yang.
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