What is he best known for?
The fields of study he is best known for:
John M. Asara spends much of his time researching Cell biology, Biochemistry, Phosphorylation, Cancer research and Signal transduction.
The study incorporates disciplines such as Molecular biology and Cell growth in addition to Cell biology.
His Phosphorylation study frequently intersects with other fields, such as PI3K/AKT/mTOR pathway.
His Cancer research research includes elements of Autophagy, Cancer, Pancreatic cancer, KRAS and MAPK/ERK pathway.
His studies deal with areas such as Cell cycle, Kinase and Pyrimidine metabolism as well as Signal transduction.
His study in PKM2 is interdisciplinary in nature, drawing from both Pyruvate dehydrogenase kinase and Pyruvate dehydrogenase phosphatase.
His most cited work include:
- HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing (3804 citations)
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy (1638 citations)
- Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism (1075 citations)
What are the main themes of his work throughout his whole career to date?
John M. Asara focuses on Cell biology, Cancer research, Biochemistry, Phosphorylation and Molecular biology.
His research on Cell biology often connects related topics like Autophagy.
His study on Cancer research also encompasses disciplines like
- Cancer cell together with Cell culture,
- Cell growth together with MAPK/ERK pathway.
His works in Glycolysis, Pyruvate kinase, Biosynthesis, Oxidative stress and Serine are all subjects of inquiry into Biochemistry.
His Phosphorylation study frequently involves adjacent topics like Kinase.
His work deals with themes such as TSC2 and Transcription factor, which intersect with mTORC1.
He most often published in these fields:
- Cell biology (46.48%)
- Cancer research (28.87%)
- Biochemistry (24.41%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (46.48%)
- Cancer research (28.87%)
- mTORC1 (11.97%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Cancer research, mTORC1, Cancer cell and Autophagy.
All of his Cell biology and Kinase and Phosphorylation investigations are sub-components of the entire Cell biology study.
His work carried out in the field of Cancer research brings together such families of science as Cancer, Breast cancer, Triple-negative breast cancer, Glycolysis and Lung cancer.
His mTORC1 study also includes
- TSC2 together with TSC1,
- Cell growth which connect with MAPK/ERK pathway.
His research in Cancer cell intersects with topics in Synthetic lethality, Cell culture, Reprogramming and Tumor progression.
His Autophagy study integrates concerns from other disciplines, such as RNA and AMPK.
Between 2017 and 2021, his most popular works were:
- An inhibitor of oxidative phosphorylation exploits cancer vulnerability. (236 citations)
- An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer (106 citations)
- Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma (101 citations)
In his most recent research, the most cited papers focused on:
Cell biology, Cancer research, Signal transduction, Kinase and Cancer cell are his primary areas of study.
His Cell biology study incorporates themes from Inflammation and Innate immune system, Immune system.
The Cancer research study combines topics in areas such as Cancer, Breast cancer, Adenocarcinoma, Transcriptome and KRAS.
His Signal transduction research integrates issues from Vibrio cholerae, Bacteria, Host and Microbiology.
His studies deal with areas such as mTORC1, Autophagy, TFEB and Phosphorylation as well as Kinase.
His research investigates the link between Cancer cell and topics such as Glycolysis that cross with problems in Oxidative phosphorylation and Fumarase.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
