What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in PI3K/AKT/mTOR pathway, Cell biology, TSC2, P70-S6 Kinase 1 and Protein kinase B.
His work deals with themes such as Cell survival and Human cancer, which intersect with PI3K/AKT/mTOR pathway.
His study focuses on the intersection of Cell biology and fields such as Cell growth with connections in the field of Molecular biology and Mechanistic target of rapamycin.
Brendan D. Manning combines subjects such as TSC1, RHEB and PTEN with his study of TSC2.
His study on P70-S6 Kinase 1 is mostly dedicated to connecting different topics, such as Cancer research.
Within one scientific family, Brendan D. Manning focuses on topics pertaining to Insulin resistance under Protein kinase B, and may sometimes address concerns connected to Cell, Bioinformatics, Disease and Neuroscience.
His most cited work include:
- AKT/PKB signaling: navigating downstream. (4442 citations)
- Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. (1284 citations)
- Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. (1284 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are mTORC1, Cell biology, PI3K/AKT/mTOR pathway, Cancer research and Protein kinase B.
His studies in mTORC1 integrate themes in fields like Endocrinology, Sterol regulatory element-binding protein and Protein kinase A.
Brendan D. Manning has researched Cell biology in several fields, including Cancer cell, Transcription factor and Cell growth.
His PI3K/AKT/mTOR pathway study improves the overall literature in Signal transduction.
His work in Cancer research covers topics such as Cancer which are related to areas like Bioinformatics.
Brendan D. Manning does research in Protein kinase B, focusing on P70-S6 Kinase 1 specifically.
He most often published in these fields:
- mTORC1 (47.83%)
- Cell biology (44.93%)
- PI3K/AKT/mTOR pathway (45.65%)
What were the highlights of his more recent work (between 2015-2021)?
- mTORC1 (47.83%)
- Cell biology (44.93%)
- PI3K/AKT/mTOR pathway (45.65%)
In recent papers he was focusing on the following fields of study:
Brendan D. Manning spends much of his time researching mTORC1, Cell biology, PI3K/AKT/mTOR pathway, Biochemistry and Cell growth.
The mTORC1 study combines topics in areas such as Cancer, Cancer research, Protein kinase A and Protein biosynthesis.
Brendan D. Manning interconnects Cell and Transcription factor in the investigation of issues within Cell biology.
His work carried out in the field of PI3K/AKT/mTOR pathway brings together such families of science as Pharmacology and Phosphorylation.
His study in TSC2 is interdisciplinary in nature, drawing from both Suppressor and TSC1.
Brendan D. Manning mostly deals with Protein kinase B in his studies of Signal transduction.
Between 2015 and 2021, his most popular works were:
- AKT/PKB Signaling: Navigating the Network (1191 citations)
- mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle. (349 citations)
- mTORC1 signaling and the metabolic control of cell growth. (243 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in mTORC1, Cell biology, Biochemistry, PI3K/AKT/mTOR pathway and Signal transduction.
The various areas that Brendan D. Manning examines in his mTORC1 study include Cancer and Protein kinase A.
His Cell biology study combines topics from a wide range of disciplines, such as Glycolysis, Oxidative phosphorylation, Hypoxia and Neovascularization.
His works in Mechanistic target of rapamycin and TSC2 are all subjects of inquiry into PI3K/AKT/mTOR pathway.
His study of Protein kinase B is a part of Signal transduction.
His biological study spans a wide range of topics, including Regulation of gene expression, Neuroscience and Insulin resistance.
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