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Christopher G. Proud

Christopher G. Proud

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Molecular Biology
Australia
2026

D-Index & Metrics

Molecular Biology

D-Index
111
Citations
48726
World Ranking
351
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Australia Leader Award
  • 2025 - Research.com Molecular Biology in Australia Leader Award
  • 2023 - Research.com Molecular Biology in Australia Leader Award
  • 2018 - Fellow of the Australian Academy of Health and Medical Science

Overview

Christopher G. Proud is affiliated with the University of Adelaide in Australia. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a notable focus on Molecular Biology, Epidemiology, Physiology, Cell Biology, and Oncology.

Their scientific work addresses key topics within these fields, including:

  • PI3K/AKT/mTOR signaling in cancer
  • RNA and protein synthesis mechanisms
  • Adipokines, inflammation, and metabolic diseases
  • Autophagy in disease and therapy
  • Metabolism, diabetes, and cancer
  • RNA research and splicing
  • RNA modifications and cancer

Among the recent papers authored adjacent to their field are:

  • Pathophysiology of obesity and its associated diseases, 2023, published in Acta Pharmaceutica Sinica B
  • Hepatic selective insulin resistance at the intersection of insulin signaling and metabolic dysfunction-associated steatotic liver disease, 2024, published in Cell Metabolism
  • Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling, 2020, published in Bioscience Reports
  • MNK Inhibition Sensitizes KRAS -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression, 2020, published in Cancer Discovery
  • eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition, 2020, published in Current Biology

Frequent coauthors in Proud's research include Jianling Xie, Xuemin Wang, Xin Jin, Timothy J. Sargeant, and Tao Bo, reflecting ongoing collaborations within their scientific community.

Their work has been disseminated frequently in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), Biochemical Journal, Journal of Biological Chemistry, and Cellular and Molecular Life Sciences.

Christopher G. Proud was recognized in 2018 as a Fellow of the Australian Academy of Health and Medical Science, an award marking their involvement and contributions to biomedical science at a national level.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

    Andrew Jan Waskiewicz;Andrea Flynn;Christopher G. Proud;Jonathan A. Cooper;Jonathan A. Cooper

  • Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase

    Xuemin Wang;Wei Li;Michayla Williams;Naohiro Terada

  • The mTOR pathway in the control of protein synthesis.

    Xuemin Wang;Christopher G. Proud

  • Signalling to translation: how signal transduction pathways control the protein synthetic machinery

    Christopher G. Proud

  • Regulation of peptide-chain elongation in mammalian cells.

    Gareth J. Browne;Christopher G. Proud

  • Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis

    Sandrine Horman;Gareth J. Browne;Ulrike Krause;Jigna V. Patel

  • Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

    G. I. Welsh;Christopher Proud

  • Regulation of mammalian translation factors by nutrients

    Christopher G. Proud

  • eIF2 and the control of cell physiology

    Christopher G. Proud

  • The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.

    Ewan M. Smith;Stephen G. Finn;Andrew R. Tee;Gareth J. Browne

  • The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase.

    Yvonne L. Woods;Philip Cohen;Walter Becker;Ross Jakes

  • The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

    Gabriel Leprivier;Marc Remke;Marc Remke;Barak Rotblat;Adrian Dubuc

  • Stimulation of the AMP-activated Protein Kinase Leads to Activation of Eukaryotic Elongation Factor 2 Kinase and to Its Phosphorylation at a Novel Site, Serine 398

    Gareth J. Browne;Stephen G. Finn;Christopher G. Proud

  • Amino acid availability regulates p70 S6 kinase and multiple translation factors.

    Xuemin Wang;Linda E. Campbell;Christa M. Miller;Christopher G. Proud

  • Activation of AMP-activated Protein Kinase Inhibits Protein Synthesis Associated with Hypertrophy in the Cardiac Myocyte

    Anita Y.M. Chan;Carrie Lynn M. Soltys;Martin E. Young;Christopher G. Proud

  • Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

    Gert C. Scheper;Christopher G. Proud

  • Regulation of translation elongation factor‐2 by insulin via a rapamycin‐sensitive signalling pathway.

    Nicholas T. Redpath;Emily J. Foulstone;Christopher Proud

  • Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

    Gavin I Welsh;Christa M Miller;A.Jane Loughlin;Nigel T Price

  • Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling.

    Aruna D. Balgi;Bruno D. Fonseca;Elizabeth Donohue;Trevor C. F. Tsang

Frequent Co-Authors

Gavin I. Welsh
Gavin I. Welsh University of Bristol
Richard M. Denton
Richard M. Denton University of Bristol
Lijun Wang
Lijun Wang Huazhong Agricultural University
Philip Cohen
Philip Cohen University of Dundee
Mark H. Rider
Mark H. Rider Université Catholique de Louvain
Didier Vertommen
Didier Vertommen Université Catholique de Louvain
Sally Martin
Sally Martin University of Queensland
Andrew C.W. Zannettino
Andrew C.W. Zannettino University of Adelaide
Hugh G. Nimmo
Hugh G. Nimmo University of Glasgow

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