Gavin I. Welsh

Overview

Best Publications

• Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

  G. I. Welsh;Christopher Proud

  542
  Citations

• Insulin signaling to the glomerular podocyte is critical for normal kidney function

  Gavin I Welsh;Lorna J Hale;Vera Eremina;Marie Jeansson

  517
  Citations

• Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

  Gavin I Welsh;Christa M Miller;A.Jane Loughlin;Nigel T Price

  385
  Citations

• Regulation of Protein Kinase B and Glycogen Synthase Kinase-3 by Insulin and β-Adrenergic Agonists in Rat Epididymal Fat Cells ACTIVATION OF PROTEIN KINASE B BY WORTMANNIN-SENSITIVE AND -INSENSITIVE MECHANISMS

  S. Kelly Moule;Gavin I. Welsh;Nigel J. Edgell;Emily J. Foulstone

  351
  Citations

• The human glomerular podocyte is a novel target for insulin action.

  Richard J M Coward;Gavin I Welsh;Jing Yang;Candida Tasman

  332
  Citations

• Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management

  Agnieszka Bierzynska;Hugh J. McCarthy;Katrina Soderquest;Ethan S. Sen

  281
  Citations

• Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase.

  Gavin I Welsh;EJ Foulstone;SW Young;Jeremy M Tavare

  278
  Citations

• WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing

  Elianna M. Amin;Sebastian Oltean;Jing Hua;Melissa V.R. Gammons

  271
  Citations

• The podocyte cytoskeleton—key to a functioning glomerulus in health and disease

  Gavin I. Welsh;Moin A. Saleem

  242
  Citations

• GSK3: a SHAGGY frog story.

  Gavin I. Welsh;Colette E. Wilson;Christopher G. Proud

  221
  Citations

• Simultaneous Sequencing of 24 Genes Associated with Steroid-Resistant Nephrotic Syndrome

  Hugh J. McCarthy;Agnieszka Bierzynska;Matt Wherlock;Milos Ognjanovic

  204
  Citations

• Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.

  Daniel C. Berwick;Ghislaine C. Dell;Gavin I. Welsh;Kate J. Heesom

  181
  Citations

• Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx.

  Anurag Singh;Anurag Singh;Raina D Ramnath;Rebecca R Foster;Emma C Wylie

  178
  Citations

• Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake.

  Laura M. Fletcher;Gavin I. Welsh;Paru B. Oatey;Jeremy M. Tavaré

  176
  Citations

• Nephrin Is Critical for the Action of Insulin on Human Glomerular Podocytes

  Richard J M Coward;Gavin I Welsh;Ania Koziell;Sagair Hussain

  171
  Citations

• Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy

  Rachel Lennon;Deborah Pons;Matthew A. Sabin;Christina Wei

  169
  Citations

• High glucose causes dysfunction of the human glomerular endothelial glycocalyx

  Anurag Singh;Vincent Friden;Ishita Dasgupta;Rebecca Rachael Foster

  164
  Citations

• Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus

  P. Anil Kumar;Gavin I. Welsh;Moin A. Saleem;Ram K. Menon

  161
  Citations

• Nephrin-signature molecule of the glomerular podocyte?

  Gavin I Welsh;Moin A Saleem

  160
  Citations

• Role of protein kinase B in insulin-regulated glucose uptake

  Gavin I Welsh;Ingeborg Hers;DC Berwick;G Dell

  160
  Citations