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Molecular Biology
Canada
2026

D-Index & Metrics

Molecular Biology

D-Index
130
Citations
72307
World Ranking
189
National Ranking
5

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Canada Leader Award
  • 2025 - Research.com Molecular Biology in Canada Leader Award
  • 2023 - Research.com Molecular Biology in Canada Leader Award
  • 2000 - Fellow of the Royal Society of Canada Academy of Science

Overview

James R. Woodgett is affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada. Their research spans various topics mainly within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

The primary subfields of study include Molecular Biology, Infectious Diseases, Cancer Research, Surgery, and Cellular and Molecular Neuroscience.

Key research topics covered by James R. Woodgett's work are:

  • Wnt/β-catenin signaling in development and cancer
  • SARS-CoV-2 detection and testing
  • Cancer-related gene regulation
  • Cancer Genomics and Diagnostics
  • Congenital heart defects research
  • Tissue Engineering and Regenerative Medicine
  • Parkinson's Disease Mechanisms and Treatments

Frequent publication venues where their work appears are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Circulation Research
  • Frontiers in Molecular Neuroscience
  • Journal of Molecular Medicine

Notable recent papers include:

  • "GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib" (2020) published in Frontiers in Molecular Neuroscience
  • "Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart" (2022) published in Circulation Research
  • "Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods" (2021) published in Virology Journal
  • "Glycogen synthase kinase-3β inhibits tubular regeneration in acute kidney injury by a FoxM1-dependent mechanism" (2020) published in The FASEB Journal
  • "GSK-3 is a master regulator of neural progenitor homeostasis" (2020) published in UNC Libraries

Frequent co-authors include:

  • Firdos Ahmad
  • Rizwan Qaisar
  • Eldad Zacksenhaus
  • Sean E. Egan
  • Joel D. Pearson

James R. Woodgett was honored as a Fellow of the Royal Society of Canada in 2000 by the Academy of Science.

Best Publications

  • The ground state of embryonic stem cell self-renewal

    Qi-Long Ying;Jason Wray;Jennifer Nichols;Laura Batlle-Morera

  • The stress-activated protein kinase subfamily of c-Jun kinases.

    John M. Kyriakis;Papia Banerjee;Eleni Nikolakaki;Eleni Nikolakaki;Tianang Dai

  • GSK-3: tricks of the trade for a multi-tasking kinase.

    Bradley W. Doble;James R. Woodgett

  • Phosphorylation of c- jun mediated by MAP kinases

    Bernd J. Pulverer;John M. Kyriakis;Joseph Avruch;Eleni Nikolakaki

  • Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

    Klaus P. Hoeflich;Juan Luo;Elizabeth A. Rubie;Ming-Sound Tsao

  • Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

    Vuk Stambolic;Laurent Ruel;James R. Woodgett

  • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

    Marc Delcommenne;Clara Tan;Virginia Gray;Laurent Rue

  • Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

    Paul J. Coffer;Jing Jin;James R. Woodgett

  • Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.

    William J. Boyle;Tod Smeal;Libert H.K. Defize;Peter Angel

  • Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun.

    Sánchez I;Hughes Rt;Mayer Bj;Mayer Bj;Yee K

  • A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation.

    Xin Zeng;Keiko Tamai;Brad Doble;Shitao Li

  • Systematic Discovery of In Vivo Phosphorylation Networks

    Rune Linding;Rune Linding;Lars Juhl Jensen;Gerard J. Ostheimer;Marcel A.T.M. van Vugt;Marcel A.T.M. van Vugt

  • Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

    Xianjun Fang;Shuang Xing Yu;Yiling Lu;Robert C. Bast

  • Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

    Jean-Martin Beaulieu;Tatyana D. Sotnikova;Wei-Dong Yao;Lisa Kockeritz

  • Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

    Diane P. Hanger;Kenneth Hughes;James R. Woodgett;Jean-Pierre Brion

  • Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

    Mlnhong Yan;Tianang Dai;Joseph C. Deak;John M. Kyriakis

  • Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation.

    V Stambolic;J R Woodgett

  • THE STRESS-ACTIVATED PROTEIN KINASE PATHWAYS

    L. A. Tibbles;J. R. Woodgett

  • Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.

    K Hughes;E Nikolakaki;S E Plyte;N F Totty

  • PKB/AKT: functional insights from genetic models

    Michael P. Scheid;James R. Woodgett

Frequent Co-Authors

Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Thomas Force
Thomas Force Vanderbilt University
Philip Cohen
Philip Cohen University of Dundee
John M. Kyriakis
John M. Kyriakis Tufts University
Vuk Stambolic
Vuk Stambolic University of Toronto
Josef M. Penninger
Josef M. Penninger University of British Columbia
Joseph Avruch
Joseph Avruch Harvard University
Erhe Gao
Erhe Gao Temple University
Tony Hunter
Tony Hunter Salk Institute for Biological Studies
Kathleen L. Gould
Kathleen L. Gould Vanderbilt University

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