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Biology and Biochemistry
Spain
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
122
Citations
52179
World Ranking
586
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Spain Leader Award
  • 2025 - Research.com Biology and Biochemistry in Spain Leader Award
  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award
  • 2022 - Research.com Biology and Biochemistry in Spain Leader Award
  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jesús Avila is affiliated with the Centro de Biología Molecular Severo Ochoa in Spain. Their research covers several interconnected areas within biochemistry, genetics, molecular biology, medicine, and neuroscience, with a particular focus on neurodegenerative diseases and neural mechanisms.

Avila's work is notably concentrated in the following main fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Their research extends into various subfields:

  • Molecular Biology
  • Physiology
  • Neurology
  • Cellular and Molecular Neuroscience
  • Genetics

The key scientific topics addressed by Avila include:

  • Alzheimer's disease research and treatments
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Prion Diseases and Protein Misfolding
  • Genetics and Neurodevelopmental Disorders
  • Memory and Neural Mechanisms

Frequent co-authors collaborating with Avila feature:

  • Félix Hernández
  • Laura Vallés-Saiz
  • Vega García-Escudero
  • Alejandro Antón-Fernández
  • Raquel Cuadros

The primary publishing venues for Avila's work include:

  • International Journal of Molecular Sciences
  • Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Alzheimer s Disease
  • Frontiers in Aging Neuroscience

Recent papers published by Avila or related to their research group are:

  • "A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease", 2020, Frontiers in Immunology
  • "GSK-3 and Tau: A Key Duet in Alzheimer's Disease", 2021, Cells
  • "Unraveling human adult hippocampal neurogenesis", 2020, Nature Protocols
  • "In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice", 2020, Stem Cell Reports
  • "Microglia in Alzheimer's Disease in the Context of Tau Pathology", 2020, Biomolecules

Jesús Avila has received recognition including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2016
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

    Elena P. Moreno-Jiménez;Elena P. Moreno-Jiménez;Miguel Flor-García;Miguel Flor-García;Julia Terreros-Roncal;Julia Terreros-Roncal;Alberto Rábano

  • Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia.

    Almudena Ramón-Cueto;M.Isabel Cordero;Fernando F. Santos-Benito;Jesús Avila

  • Role of tau protein in both physiological and pathological conditions.

    Jesús Ávila;José Javier Lucas;Mar Pérez;Félix Hernández

  • Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice

    José Javier Lucas;José Javier Lucas;Félix Hernández;Félix Hernández;Pilar Gómez-Ramos;María A. Morán

  • Long-Distance Axonal Regeneration in the Transected Adult Rat Spinal Cord Is Promoted by Olfactory Ensheathing Glia Transplants

    Almudena Ramón-Cueto;Giles W. Plant;Jesus Avila;Mary Bartlett Bunge;Mary Bartlett Bunge

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Glycogen synthase kinase 3: a drug target for CNS therapies

    Ratan V. Bhat;Samantha L. Budd Haeberlein;Jesús Avila

  • Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418

    Ratan Bhat;Yafeng Xue;Stefan Berg;Sven Hellberg

  • Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function.

    Carlos Sánchez;Javier Díaz-Nido;Jesús Ávila

  • GSK-3β, a pivotal kinase in Alzheimer disease

    María Llorens-Martín;María Llorens-Martín;Jerónimo Jurado;Félix Hernández;Jesús Avila

  • Olfactory ensheathing glia: properties and function

    Almudena Ramón-Cueto;Jesús Avila

  • Polymerization of τ into filaments in the presence of heparin: The minimal sequence required for τ - τ interaction

    Mar Pérez;José M. Valpuesta;Miguel Medina;Esteban Montejo de Garcini

  • Analysis of microtubule-associated protein tau glycation in paired helical filaments.

    M D Ledesma;P Bonay;C Colaço;J Avila

  • Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.

    Claudie Hooper;V Markevich;Florian Plattner;Richard Killick

  • Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

    George Perry;Akihiko Nunomura;Akihiko Nunomura;Keisuke Hirai;Keisuke Hirai;Xiongwei Zhu

  • Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons

    Juan Ramón Muñoz-Montaño;Francisco J. Moreno;Jesús Avila;Javier Dı́az-Nido

  • Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments.

    Félix Hernández;José Borrell;Carmen Guaza;Jesús Avila

  • A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo

    Lídia Serenó;Mireia Coma;M. Rodríguez;P. Sánchez-Ferrer

  • Lithium protects cultured neurons against β-amyloid-induced neurodegeneration

    Gema Alvarez;Juan Ramón Muñoz-Montaño;Jorgina Satrústegui;Jesús Avila

  • Microtubule Reduction in Alzheimer’s Disease and Aging Is Independent of τ Filament Formation

    Adam D. Cash;Gjumrakch Aliev;Sandra L. Siedlak;Akihiko Nunomura

Frequent Co-Authors

Félix Hernández
Félix Hernández Jaume I University
Javier Díaz-Nido
Javier Díaz-Nido Spanish National Research Council
María Llorens-Martín
María Llorens-Martín Spanish National Research Council
José J. Lucas
José J. Lucas Spanish National Research Council
George Perry
George Perry The University of Texas at San Antonio
Francisco Wandosell
Francisco Wandosell Spanish National Research Council
Javier DeFelipe
Javier DeFelipe Technical University of Madrid
Mark A. Smith
Mark A. Smith Case Western Reserve University
Eduardo Soriano
Eduardo Soriano University of Barcelona
Miguel Díaz-Hernández
Miguel Díaz-Hernández Complutense University of Madrid

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