Toshiaki Katada

Overview

Best Publications

• Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.

  Toshiaki Katada;Michio Ui

  1137
  Citations

• Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase.

  Toshiaki Katada;Alfred G. Gilman;Yasuhiro Watanabe;Silvia Bauer

  995
  Citations

• Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model.

  Makoto Tamura;Katsumi Nogimori;Satoshi Murai;Motoyuki Yajima

  718
  Citations

• Specific uncoupling by islet-activating protein, pertussis toxin, of negative signal transduction via alpha-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells.

  H Kurose;T Katada;T Amano;M Ui

  697
  Citations

• The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.

  T Katada;G M Bokoch;J K Northup;M Ui

  558
  Citations

• Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

  H. Itoh;T. Kozasa;S. Nagata;S. Nakamura

  445
  Citations

• Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.

  T Katada;M Oinuma;M Ui

  434
  Citations

• A simple structure encodes G protein-activating function of the IGF-II/mannose 6-phosphate receptor

  Takashi Okamoto;Toshiaki Katada;Yoshitake Murayama;Michio Ui

  396
  Citations

• The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.

  T Katada;J K Northup;G M Bokoch;M Ui

  382
  Citations

• Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by islet-activating protein, pertussis toxin. A possible role of the toxin substrate in Ca2+-mobilizing receptor-mediated signal transduction.

  F Okajima;T Katada;M Ui

  374
  Citations

• Heterodimeric Phosphoinositide 3-Kinase Consisting of p85 and p110β Is Synergistically Activated by the βγ Subunits of G Proteins and Phosphotyrosyl Peptide

  Hiroshi Kurosu;Tomohiko Maehama;Taro Okada;Toshiyoshi Yamamoto

  373
  Citations

• The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.

  Shin-ichi Hoshino;Mariko Imai;Tetsuo Kobayashi;Naoyuki Uchida

  360
  Citations

• Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells. Reconstitution with Gi or Go of the plasma membranes ADP-ribosylated by pertussis toxin.

  A Kikuchi;O Kozawa;K Kaibuchi;T Katada

  359
  Citations

• A Novel Role of the Mammalian GSPT/eRF3 Associating with Poly(A)-binding Protein in Cap/Poly(A)-dependent Translation *

  Naoyuki Uchida;Shin-ichi Hoshino;Hiroaki Imataka;Nahum Sonenberg

  324
  Citations

• GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease.

  Genta Ito;Takuro Okai;Go Fujino;Kohsuke Takeda

  321
  Citations

• Mechanisms for inhibition of the catalytic activity of adenylate cyclase by the guanine nucleotide-binding proteins serving as the substrate of islet-activating protein, pertussis toxin.

  T Katada;M Oinuma;M Ui

  313
  Citations

• Differential activation of adenylyl cyclase by protein kinase C isoenzymes.

  J.-I. Kawabe;G. Iwami;T. Ebina;S. Ohno

  302
  Citations

• Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast.

  Yasuhiro Araki;Shinya Takahashi;Tetsuo Kobayashi;Hiroaki Kajiho

  299
  Citations

• The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein

  Toshiaki Katada;Makoto Tamura;Michio Ui

  284
  Citations

• A new GTP-binding protein in brain tissues serving as the specific substrate of islet-activating protein, pertussis toxin

  Toshiaki Katada;Masayuki Oinuma;Kayoko Kusakabe;Michio Ui

  257
  Citations