World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
140
Citations
68069
World Ranking
276
National Ranking
188

Overview

Lutz Birnbaumer is affiliated with the National Institutes of Health in the United States and has contributed extensively to research in medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their work covers a range of topics centered on ion channels and receptors, receptor mechanisms and signaling, and neurobiology, among others.

Their research has focused on several specific areas, including:

  • Ion Channels and Receptors
  • Ion channel regulation and function
  • Neurobiology and Insect Physiology Research
  • Receptor Mechanisms and Signaling
  • Circadian rhythm and melatonin
  • Biochemical Analysis and Sensing Techniques
  • Olfactory and Sensory Function Studies

Birnbaumer has published extensively on molecular biology, sensory systems, cellular and molecular neuroscience, immunology, and pulmonary and respiratory medicine. Key subfields of study include:

  • Molecular Biology
  • Sensory Systems
  • Cellular and Molecular Neuroscience
  • Immunology
  • Pulmonary and Respiratory Medicine

Notable recent papers authored or co-authored by Birnbaumer include:

  • "Quercetin alleviates acute kidney injury by inhibiting ferroptosis," 2020, Journal of Advanced Research
  • "Reinvigorating exhausted CD8+ cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy," 2020, Medicinal Research Reviews
  • "Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice," 2021, Hepatology
  • "Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders," 2021, Cell Reports
  • "PLAGL2-EGFR-HIF-1/2α Signaling Loop Promotes HCC Progression and Erlotinib Insensitivity," 2020, Hepatology

Their research findings have appeared frequently in well-recognized publication venues, such as:

  • Proceedings of the National Academy of Sciences
  • Hepatology
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife

Collaboration has been a significant aspect of their scientific output. Frequent co-authors include:

  • Marc Freichel
  • Yong Yang
  • Alexander Dietrich
  • Sebastián Susperreguy
  • Tiffany M. Schmidt

Best Publications

  • Receptor-effector coupling by G proteins

    Lutz Birnbaumer;Joel Abramowitz;Arthur M. Brown

  • The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver V. AN OBLIGATORY ROLE OF GUANYL NUCLEOTIDES IN GLUCAGON ACTION

    Martin Rodbell;Lutz Birnbaumer;Stephen L. Pohl;Hendrik Michiel Jan Krans

  • Letter to the EditorNomenclature of Voltage-Gated Calcium Channels

    Eric A. Ertel;Kevin P. Campbell;Michael M. Harpold;Franz Hofmann

  • The TRP channels, a remarkably functional family.

    Craig Montell;Lutz Birnbaumer;Veit Flockerzi

  • A Unified Nomenclature for the Superfamily of TRP Cation Channels

    Craig Montell;Lutz Birnbaumer;Veit Flockerzi;René J. Bindels

  • trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry

    Xi Zhu;Meisheng Jiang;Michael Peyton;Guylain Boulay

  • A G protein directly regulates mammalian cardiac calcium channels.

    Atsuko Yatani;Juan Codina;Yutaka Imoto;John P. Reeves

  • Functional interaction between InsP3 receptors and store-operated Htrp3 channels.

    Kirill Kiselyov;Xin Xu;Galina Mozhayeva;Tuan Kuo

  • Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels.

    Hong-Tao Ma;Randen L. Patterson;Damian B. van;Rossum

  • G Proteins in Signal Transduction

    L Birnbaumer

  • Receptor-to-effector signaling through G proteins: Roles for βγ dimers as well as α subunits

    Lutz Birnbaumer

  • Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes.

    G. E. Kirsch;J. Codina;L. Birnbaumer;A. M. Brown

  • Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice

    Uwe Rudolph;Milton J. Finegold;Susan S. Rich;Gregory R. Harriman

  • The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver I. PROPERTIES

    Stephen L. Pohl;Lutz Birnbaumer;Martin Rodbell

  • Increased Vascular Smooth Muscle Contractility in TRPC6 −/− Mice

    Alexander Dietrich;Michael Mederos y Schnitzler;Maik Gollasch;Volkmar Gross

  • The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. VI. Evidence for a role of membrane lipids.

    Stephen L. Pohl;H. Michiel J. Krans;Vladimir Kozyreff;Lutz Birnbaumer

  • The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon.

    M Rodbell;H M Krans;S L Pohl;L Birnbaumer

  • Adenyl cyclase in fat cells. II. Hormone receptors.

    Lutz Birnbaumer;Martin Rodbell

  • Ionic channels and their regulation by G protein subunits.

    Arthur M. Brown;Lutz Birnbaumer

  • Modulation of Ca2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca2+ entry

    Guylain Boulay;Darren M. Brown;Ning Qin;Meisheng Jiang

Frequent Co-Authors

Juan Codina
Juan Codina Wake Forest University
Alexander Dietrich
Alexander Dietrich Ludwig-Maximilians-Universität München
Marc Freichel
Marc Freichel Heidelberg University
Enrico Stefani
Enrico Stefani University of California, Los Angeles
Ravi Iyengar
Ravi Iyengar Icahn School of Medicine at Mount Sinai
Veit Flockerzi
Veit Flockerzi Saarland University
Edward Perez-Reyes
Edward Perez-Reyes University of Virginia
Martin Rodbell
Martin Rodbell National Institutes of Health
Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Bernd Nürnberg
Bernd Nürnberg University of Tübingen

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