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Biology and Biochemistry

D-Index
87
Citations
28336
World Ranking
2823
National Ranking
1451

Overview

Ravi Iyengar is a researcher affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their work spans multiple fields, primarily within biochemistry, genetics, and molecular biology, as well as medicine.

Their research portfolio includes contributions to a variety of scientific topics, notably:

  • Bioinformatics and Genomic Networks
  • Single-cell and Spatial Transcriptomics
  • Chronic Kidney Disease and Diabetes
  • Spinal Cord Injury Research
  • Gene Regulatory Network Analysis
  • Renal and Related Cancers
  • Biomedical Text Mining and Ontologies

Key recent publications by Iyengar include:

  • "An atlas of healthy and injured cell states and niches in the human kidney," 2023, published in Nature
  • "Clinical features of COVID-19 mortality: development and validation of a clinical prediction model," 2020, published in The Lancet Digital Health
  • "Rationale and design of the Kidney Precision Medicine Project," 2021, published in Kidney International
  • "A reference tissue atlas for the human kidney," 2022, published in Science Advances
  • "A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project," 2020, published in Physiological Genomics

Their frequent coauthors include:

  • Jens Hansen
  • Evren U. Azeloglu
  • Yuguang Xiong
  • Mustafa M. Siddiq
  • Theodore Alexandrov

Ravi Iyengar often publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Kidney International
  • Frontiers in Pharmacology
  • Journal of the American Society of Nephrology
  • Nature Reviews Nephrology

Their work demonstrates a focused engagement with nephrology, molecular biology, genetics, pathology, and pulmonary and respiratory medicine as subfields, reflecting a diverse yet linked research interest across these biomedical sciences.

Best Publications

  • Emergent Properties of Networks of Biological Signaling Pathways

    Upinder S. Bhalla;Ravi Iyengar

  • G Protein Pathways

    Susana R. Neves;Prahlad T. Ram;Ravi Iyengar

  • Functional atlas of the integrin adhesome

    Ronen Zaidel-Bar;Shalev Itzkovitz;Avi Ma'ayan;Ravi Iyengar

  • Complexity in Biological Signaling Systems

    Gezhi Weng;Upinder S. Bhalla;Ravi Iyengar

  • MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network

    Upinder S. Bhalla;Prahlad T. Ram;Ravi Iyengar

  • Molecular Basis for Interactions of G Protein βγ Subunits with Effectors

    Carolyn E. Ford;Nikolai P. Skiba;Hyunsu Bae;Yehia Daaka

  • Signaling Networks: The Origins of Cellular Multitasking

    J.Dedrick Jordan;Emmanuel M Landau;Ravi Iyengar

  • Gating of CaMKII by cAMP-Regulated Protein Phosphatase Activity During LTP

    Robert D. Blitzer;John H. Connor;George P. Brown;Tony Wong

  • Network analyses in systems pharmacology

    Seth I. Berger;Ravi Iyengar

  • Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

    Viviana Cordeddu;Elia Di Schiavi;Len A. Pennacchio;Len A. Pennacchio;Avi Ma’ayan

  • The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

    Alexandra B. Keenan;Sherry L. Jenkins;Kathleen M. Jagodnik;Simon Koplev

  • The G protein-gated atrial K + channel is stimulated by three distinct G I α-subunits

    Atsuko Yatani;Rafael Mattera;Juan Codina;Rolf Graf

  • Molecular and functional diversity of mammalian Gs-stimulated adenylyl cyclases.

    Ravi Iyengar

  • Formation of Regulatory Patterns During Signal Propagation in a Mammalian Cellular Network

    Avi Ma'ayan;Sherry L. Jenkins;Susana Neves;Anthony Hasseldine

  • Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins

    John D. Hildebrandt;Ronald D. Sekura;Juan Codina;Ravi Iyengar

  • Systems Pharmacology: Network Analysis to Identify Multiscale Mechanisms of Drug Action

    Shan Zhao;Ravi Iyengar

  • Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium

    Juan Codina;John Hildebrandt;Ravi Iyengar;Lutz Birnbaumer

  • Ns and Ni, the stimulatory and inhibitory regulatory components of adenylyl cyclases. Purification of the human erythrocyte proteins without the use of activating regulatory ligands.

    J Codina;J D Hildebrandt;R D Sekura;M Birnbaumer

  • Systems approaches to polypharmacology and drug discovery.

    Aislyn D W Boran;Ravi Iyengar

  • Cell Shape and Negative Links in Regulatory Motifs Together Control Spatial Information Flow in Signaling Networks

    Susana R. Neves;Panayiotis Tsokas;Anamika Sarkar;Elizabeth A. Grace

Frequent Co-Authors

Avi Ma'ayan
Avi Ma'ayan Icahn School of Medicine at Mount Sinai
Lutz Birnbaumer
Lutz Birnbaumer National Institutes of Health
Richard T. Premont
Richard T. Premont University Hospitals of Cleveland
Juan Codina
Juan Codina Wake Forest University
Ronald A. Li
Ronald A. Li University of Hong Kong
James Hone
James Hone Columbia University
Vivette D. D'Agati
Vivette D. D'Agati Columbia University
Olga G. Troyanskaya
Olga G. Troyanskaya Princeton University
Theodore Alexandrov
Theodore Alexandrov European Molecular Biology Laboratory
Matthias Kretzler
Matthias Kretzler University of Michigan–Ann Arbor

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