H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Neuroscience H-index 158 Citations 100,877 412 World Ranking 31 National Ranking 19

Research.com Recognitions

Awards & Achievements

2021 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

2019 - Member of the National Academy of Engineering For molecular and optical tools for discovery and control of neuronal signals behind animal behavior in health and disease.

2019 - Warren Alpert Foundation Prize For the development of optogenetics as a way to control the activity of specific circuits in the nervous system, to determine their function and ultimately to control them to treat neurological and psychiatric disorders.

2018 - Canada Gairdner International Award

2018 - Fellow, National Academy of Inventors

2017 - Fellow of the Indian National Academy of Engineering (INAE)

2016 - Breakthrough Prize in Life Sciences for the development and implementation of optogenetics – the programming of neurons to express light-activated ion channels and pumps, so that their electrical activity can be controlled by light.

2015 - Albany Medical Center Prize in Medicine and Biomedical Research

2015 - BBVA Foundation Frontiers of Knowledge Award

2015 - Lurie Prize in Biomedical Sciences, Foundation for the National Institutes of Health

2014 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences

2014 - Keio Medical Science Prize, Keio University, Tokyo, Japan

2013 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for pioneering the technology called optogenetics in which insertion of a single bacterial protein into a neuron allows exquisite control of the neuron with light.

2013 - Robert J. and Claire Pasarow Foundation Medical Research Award

2013 - The Brain Prize, Lundbeck Foundation For their invention and refinement of optogenetics. This revolutionary technique allows genetically specified populations of neurons to be turned on or off with light, offering not only the ability to elucidate the characteristics of normal and abnormal neural circuitry but also new approaches to treatment of brain disorders

2012 - Member of the National Academy of Sciences

2011 - Perl-UNC Prize, University of North Carolina at Chapel Hill Development and Application of Optogenetics for Studying Neural Circuit Functions.

2011 - W. Alden Spencer Award, College of Physicians and Surgeons

2010 - Member of the National Academy of Medicine (NAM)

2009 - Golden Brain Award, Minerva Foundation

2005 - National Institutes of Health Director's Pioneer Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Neuroscience
  • Gene
  • Neuron

His primary areas of study are Neuroscience, Optogenetics, Channelrhodopsin, Dopamine and Biological neural network. As part of one scientific family, Karl Deisseroth deals mainly with the area of Neuroscience, narrowing it down to issues related to the Anatomy, and often Basal ganglia. His research integrates issues of Nucleus accumbens, Stimulation and Inhibitory postsynaptic potential, Excitatory postsynaptic potential in his study of Optogenetics.

His research in Channelrhodopsin focuses on subjects like Biophysics, which are connected to Rhodopsin, CLARITY and Biochemistry. As part of the same scientific family, Karl Deisseroth usually focuses on Dopamine, concentrating on Anhedonia and intersecting with Functional magnetic resonance imaging. His studies in Biological neural network integrate themes in fields like Cerebral cortex, Central nucleus of the amygdala, Mammalian brain, Anxiety and Brain activity and meditation.

His most cited work include:

  • Millisecond-timescale, genetically targeted optical control of neural activity. (3290 citations)
  • Driving fast-spiking cells induces gamma rhythm and controls sensory responses (1849 citations)
  • Parvalbumin neurons and gamma rhythms enhance cortical circuit performance (1805 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Neuroscience, Optogenetics, Channelrhodopsin, Biological neural network and Stimulation. His Neuroscience study focuses mostly on Dopamine, Excitatory postsynaptic potential, Inhibitory postsynaptic potential, Neuron and Prefrontal cortex. His research related to Ventral tegmental area and Dopaminergic might be considered part of Dopamine.

He frequently studies issues relating to Neurotransmission and Excitatory postsynaptic potential. Karl Deisseroth interconnects Electrophysiology, Nucleus accumbens, Anatomy, Premovement neuronal activity and Opsin in the investigation of issues within Optogenetics. His Channelrhodopsin research focuses on subjects like Biophysics, which are linked to Ion channel.

He most often published in these fields:

  • Neuroscience (83.61%)
  • Optogenetics (56.36%)
  • Channelrhodopsin (15.16%)

What were the highlights of his more recent work (between 2018-2021)?

  • Neuroscience (83.61%)
  • Optogenetics (56.36%)
  • Cell type (7.35%)

In recent papers he was focusing on the following fields of study:

His main research concerns Neuroscience, Optogenetics, Cell type, Transcriptome and Cell. His studies deal with areas such as Zebrafish and Calcium imaging as well as Neuroscience. His study of Channelrhodopsin is a part of Optogenetics.

He has included themes like RNA, Genome, Transcription and Cell biology in his Transcriptome study. His Cell research incorporates elements of HEK 293 cells, Gene expression and Caenorhabditis elegans. His studies examine the connections between Biological neural network and genetics, as well as such issues in Intracranial surgery, with regards to Nervous system.

Between 2018 and 2021, his most popular works were:

  • A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System. (136 citations)
  • A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System. (136 citations)
  • Cortical layer–specific critical dynamics triggering perception (135 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Neuroscience
  • Neuron

Karl Deisseroth focuses on Neuroscience, Optogenetics, Dopamine, Premovement neuronal activity and Extramural. The Neuroscience study combines topics in areas such as Glutamate receptor and Zebrafish. Channelrhodopsin is the focus of his Optogenetics research.

His Dopamine research includes themes of Midbrain, Glutamatergic and Aversive Stimulus. His Premovement neuronal activity study combines topics in areas such as Cortex, Opsin, Stimulation and Macaque. His Neuron study incorporates themes from Thalamic reticular nucleus, Working memory, Prefrontal cortex, Cognition and Coupling.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Millisecond-timescale, genetically targeted optical control of neural activity.

Edward S Boyden;Feng Zhang;Ernst Bamberg;Georg Nagel.
Nature Neuroscience (2005)

4516 Citations

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

Jessica A. Cardin;Marie Carlén;Marie Carlén;Konstantinos Meletis;Konstantinos Meletis;Ulf Knoblich.
Nature (2009)

2252 Citations

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

Vikaas S. Sohal;Feng Zhang;Ofer Yizhar;Karl Deisseroth.
Nature (2009)

2233 Citations

Neocortical excitation/inhibition balance in information processing and social dysfunction

Ofer Yizhar;Ofer Yizhar;Lief E. Fenno;Matthias Prigge;Franziska Schneider.
Nature (2011)

1869 Citations

Multimodal fast optical interrogation of neural circuitry

Feng Zhang;Li-Ping Wang;Martin Brauner;Jana F. Liewald.
Nature (2007)

1815 Citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

Haruhiko Bito;Karl Deisseroth;Richard W Tsien.
Cell (1996)

1329 Citations

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

Antoine Roger Adamantidis;Feng Zhang;Alexander M Aravanis;Karl Deisseroth.
Nature (2007)

1253 Citations

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

Hsing-Chen Tsai;Feng Zhang;Antoine Roger Adamantidis;Garret D Stuber.
Science (2009)

1207 Citations

Optogenetic stimulation of a hippocampal engram activates fear memory recall

Xu Liu;Steve Ramirez;Petti T. Pang;Corey B. Puryear.
Nature (2012)

1193 Citations

Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity

Karl Deisseroth;Haruhiko Bito;Richard W Tsien.
Neuron (1996)

801 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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