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Neuroscience

D-Index
66
Citations
14732
World Ranking
3020
National Ranking
37

Overview

Akihiro Yamanaka is affiliated with Nagoya University in Japan and has contributed extensively to the field of neuroscience, with a publication record primarily focused on cognitive neuroscience, cellular and molecular neuroscience, and endocrine and autonomic systems. Their research encompasses topics related to sleep and wakefulness, circadian rhythms, photoreceptor and optogenetics research, neurotransmitter receptor influence on behavior, neuropharmacology, and neuroendocrine regulation.

Their recent papers include:

  • Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice (2020, Nature Neuroscience)
  • The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus (2020, Science Advances)
  • A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning (2022, Nature Neuroscience)
  • Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses (2022, Science Advances)
  • Remote control of neural function by X-ray-induced scintillation (2021, Nature Communications)

Frequent co-authors in Yamanaka's work include Yasutaka Mukai, Kenji F. Tanaka, Daisuke Ono, Takayuki Yamashita, and Kiyofumi Yamada. This network of collaborators reflects ongoing partnerships in advancing understanding within neuroscience.

Academic publications by Yamanaka have appeared frequently in several venues, notable among them are:

  • Molecular Brain
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Frontiers in Neuroscience
  • Science Advances

Yamanaka's research addresses key areas of neuroscience with a strong emphasis on mechanisms underlying sleep, circadian rhythms, and behavior influenced by neurotransmitter receptors.

Best Publications

  • Hypothalamic orexin neurons regulate arousal according to energy balance in mice.

    Akihiro Yamanaka;Carsten T. Beuckmann;Jon T. Willie;Junko Hara

  • Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.

    Takeshi Sakurai;Ruby Nagata;Akihiro Yamanaka;Hiroko Kawamura

  • Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response

    Raphaëlle Winsky-Sommerer;Akihiro Yamanaka;Sabrina Diano;Erzsebet Borok

  • Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean

    Masahisa Yamada;Tsuyoshi Miyakawa;Tsuyoshi Miyakawa;Alokesh Duttaroy;Akihiro Yamanaka

  • Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.

    Koji Toshinai;Hideki Yamaguchi;Yuxiang Sun;Roy G. Smith

  • A Top-Down Cortical Circuit for Accurate Sensory Perception.

    Satoshi Manita;Takayuki Suzuki;Chihiro Homma;Takashi Matsumoto

  • Orexins activate histaminergic neurons via the orexin 2 receptor.

    Akihiro Yamanaka;Natsuko Tsujino;Hisayuki Funahashi;Kazuki Honda

  • Regulation of orexin neurons by the monoaminergic and cholinergic systems

    Akihiro Yamanaka;Yo Muraki;Natsuko Tsujino;Katsutoshi Goto

  • Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose‐responsive neurons to regulate Ca2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus

    Shinji Muroya;Shinji Muroya;Hisayuki Funahashi;Akihiro Yamanaka;Daisuke Kohno

  • Orexin-induced food intake involves neuropeptide Y pathway.

    Akihiro Yamanaka;Kaiko Kunii;Tadahiro Nambu;Natsuko Tsujino

  • Optogenetic activation of dorsal raphe serotonin neurons enhances patience for future rewards

    Kayoko W. Miyazaki;Katsuhiko Miyazaki;Kenji F. Tanaka;Akihiro Yamanaka

  • Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight.

    Akihiro Yamanaka;Takeshi Sakurai;Takuo Katsumoto;Masashi Yanagisawa

  • Acute Optogenetic Silencing of Orexin/Hypocretin Neurons Induces Slow-Wave Sleep in Mice

    Tomomi Tsunematsu;Thomas S. Kilduff;Edward Stuart Boyden;Satoru Takahashi

  • Orexins/hypocretins regulate drinking behaviour.

    Kaiko Kunii;Akihiro Yamanaka;Tadahiro Nambu;Ichiyo Matsuzaki

  • Serotonergic Regulation of the Orexin/Hypocretin Neurons through the 5-HT1A Receptor

    Yo Muraki;Akihiro Yamanaka;Natsuko Tsujino;Thomas S. Kilduff

  • The physiological role of orexin/hypocretin neurons in the regulation of sleep/wakefulness and neuroendocrine functions.

    Ayumu Inutsuka;Akihiro Yamanaka;Akihiro Yamanaka

  • Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins.

    Yun Zhu;Yoshihiro Miwa;Akihiro Yamanaka;Toshihiko Yada

  • Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation.

    Tomomi Tsunematsu;Takafumi Ueno;Sawako Tabuchi;Ayumu Inutsuka

  • Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function

    Sawako Tabuchi;Sawako Tabuchi;Sawako Tabuchi;Tomomi Tsunematsu;Tomomi Tsunematsu;Sarah W. Black;Makoto Tominaga;Makoto Tominaga

  • Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8

    Hirokazu Tanaka;Tetsuo Yoshida;Norimasa Miyamoto;Toshiyuki Motoike

Frequent Co-Authors

Katsutoshi Goto
Katsutoshi Goto University of Tsukuba
Kenji F. Tanaka
Kenji F. Tanaka Keio University
Thomas S. Kilduff
Thomas S. Kilduff SRI International
Michiko Narita
Michiko Narita Tokyo Medical University
Kenji Sakimura
Kenji Sakimura Niigata University
Manabu Abe
Manabu Abe Niigata University
Yugo Fukazawa
Yugo Fukazawa University of Fukui
Itaru Imayoshi
Itaru Imayoshi Kyoto University
Yuchio Yanagawa
Yuchio Yanagawa Gunma University
Kazue Mizumura
Kazue Mizumura Nihon University

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