What is he best known for?
The fields of study he is best known for:
His main research concerns Molecular biology, Cancer research, microRNA, Regulation of gene expression and DNA methylation.
Samson T. Jacob has researched Molecular biology in several fields, including Gene expression, Methyltransferase, DNA methyltransferase, Chromatin and Gene silencing.
The concepts of his Cancer research study are interwoven with issues in Carcinogenesis, Cell culture, Ectopic expression and Downregulation and upregulation.
His microRNA study frequently links to other fields, such as Cell growth.
His Regulation of gene expression study combines topics from a wide range of disciplines, such as Normal diet and Gene expression profiling.
His work carried out in the field of DNA methylation brings together such families of science as Methylation and Epigenetics.
His most cited work include:
- MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer (2192 citations)
- MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1 (616 citations)
- Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas (559 citations)
What are the main themes of his work throughout his whole career to date?
Samson T. Jacob focuses on Molecular biology, Cancer research, DNA methylation, Internal medicine and Methylation.
His Molecular biology research includes elements of Promoter, Chromatin immunoprecipitation, Gene expression, Transcription factor and Methyltransferase.
His Cancer research research incorporates themes from Protein tyrosine phosphatase, Carcinogenesis, Downregulation and upregulation, Ectopic expression and microRNA.
Samson T. Jacob combines subjects such as Regulation of gene expression and Fatty liver with his study of Carcinogenesis.
The various areas that Samson T. Jacob examines in his microRNA study include Cell culture, Cell growth and Gene expression profiling.
His DNA methylation research includes themes of Chromatin, Gene silencing and Epigenetics.
He most often published in these fields:
- Molecular biology (44.30%)
- Cancer research (31.65%)
- DNA methylation (13.29%)
What were the highlights of his more recent work (between 2016-2021)?
- Cancer research (31.65%)
- Sorafenib (4.43%)
- Hepatocellular carcinoma (6.96%)
In recent papers he was focusing on the following fields of study:
Samson T. Jacob mainly focuses on Cancer research, Sorafenib, Hepatocellular carcinoma, Cell biology and Internal medicine.
The concepts of his Cancer research study are interwoven with issues in Cancer cell, Downregulation and upregulation, MiR-122, Hepatitis and PI3K/AKT/mTOR pathway.
His Cancer cell study integrates concerns from other disciplines, such as Protein kinase B and Cell growth.
Samson T. Jacob combines subjects such as Regulation of gene expression and Ectopic expression with his study of MiR-122.
Samson T. Jacob interconnects Methyltransferase, Transcription and DNA in the investigation of issues within Cell biology.
His Internal medicine research incorporates elements of Endocrinology, Oncology and Phosphorylation.
Between 2016 and 2021, his most popular works were:
- A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis (112 citations)
- CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons. (51 citations)
- Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model (47 citations)
In his most recent research, the most cited papers focused on:
Samson T. Jacob mostly deals with Cancer research, Hepatocellular carcinoma, PI3K/AKT/mTOR pathway, Sorafenib and Downregulation and upregulation.
His studies deal with areas such as Glycosylation, Regulation of gene expression, microRNA and L1 as well as Cancer research.
His work carried out in the field of Hepatocellular carcinoma brings together such families of science as Tumor necrosis factor alpha, Immunology, Hepatitis and Chemokine.
His PI3K/AKT/mTOR pathway research includes elements of Cell cycle, AMPK and Imatinib.
Samson T. Jacob has researched Sorafenib in several fields, including Cell cycle checkpoint, CD44, mTORC1, mTORC2 and Everolimus.
His work deals with themes such as Cancer cell, MiR-122 and Ectopic expression, which intersect with Downregulation and upregulation.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
