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2026

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Medicine

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Citations
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Research.com Recognitions

  • 2026 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2017 - Member of the National Academy of Sciences
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Stephen B. Baylin is affiliated with Johns Hopkins University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. Within these broader fields, their work delves into several subfields including Molecular Biology, Oncology, Immunology, Cancer Research, and Infectious Diseases.

The main topics addressed in their research include Epigenetics and DNA Methylation, RNA modifications and cancer, Cancer Immunotherapy and Biomarkers, Cancer Genomics and Diagnostics, interferon and immune responses, Immune cells in cancer, and Histone Deacetylase Inhibitors Research.

Baylin has contributed to numerous publications across a variety of scientific journals and platforms. Frequent venues where their work has appeared include Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Nature Communications, and Nature.

Notable recent papers authored or co-authored by Baylin include:

  • Pan-cancer analysis of whole genomes, 2020, Nature
  • Comprehensive molecular characterization of mitochondrial genomes in human cancers, 2020, Nature Genetics
  • Epigenetic therapy inhibits metastases by disrupting premetastatic niches, 2020, Nature
  • Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia, 2021, Nature Cancer
  • Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer, 2020, Nature Cancer

Baylin collaborates frequently with several co-authors, reflecting an extensive research network. Prominent collaborators include Michael J. Topper, Afshin Beheshti, Eve Syrkin Wurtele, Douglas C. Wallace, and Hariharan Easwaran.

Their professional recognitions include election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2020. Additionally, Baylin is a Member of the National Academy of Sciences since 2017 and belongs to the Association of American Physicians.

Best Publications

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Comprehensive molecular characterization of human colon and rectal cancer

    Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh

  • Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

    James G. Herman;Jeremy R. Graff;Sanna Myohanen;Barry D. Nelkin

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • The fundamental role of epigenetic events in cancer

    Peter A. Jones;Stephen B. Baylin

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • Comprehensive molecular characterization of gastric adenocarcinoma

    Adam J. Bass;Vesteinn Thorsson;Ilya Shmulevich;Sheila M. Reynolds

  • Integrated genomic characterization of endometrial carcinoma

    Gad Getz;Stacey B. Gabriel;Kristian Cibulskis;Eric Lander

  • The epigenomics of cancer.

    Peter A. Jones;Stephen B. Baylin

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Eric A. Collisson;Joshua D. Campbell;Angela N. Brooks;Angela N. Brooks;Alice H. Berger

  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    Michael S. Lawrence;Carrie Sougnez;Lee Lichtenstein;Kristian Cibulskis

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Gene Silencing in Cancer in Association with Promoter Hypermethylation

    James G. Herman;Stephen B. Baylin

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Mutations in the p53 gene occur in diverse human tumour types

    J M Nigro;S J Baker;A C Preisinger;J M Jessup

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

James G. Herman
James G. Herman University of Pittsburgh
Jean Pierre J. Issa
Jean Pierre J. Issa Temple University
Peter W. Laird
Peter W. Laird Van Andel Institute
Gad Getz
Gad Getz Broad Institute
Daniel J. Weisenberger
Daniel J. Weisenberger University of Southern California
Matthew Meyerson
Matthew Meyerson Harvard University
Leslie Cope
Leslie Cope Johns Hopkins University School of Medicine
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center
Rameen Beroukhim
Rameen Beroukhim Harvard University
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute

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