World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
97
Citations
31040
World Ranking
1478
National Ranking
569

Biology and Biochemistry

D-Index
101
Citations
33228
World Ranking
1466
National Ranking
834

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Liang Tong is affiliated with Columbia University in the United States and works primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their subfields of study include Molecular Biology, Materials Chemistry, Electrical and Electronic Engineering, Genetics, and Automotive Engineering. The scientist's research encompasses several main topics such as RNA modifications and cancer, RNA research and splicing, RNA and protein synthesis mechanisms, crystallization and solubility studies, X-ray diffraction in crystallography, bacterial biofilms and quorum sensing, and fuel cells and related materials.

Among their recent publications are the following papers:

  • Structure of an active human histone pre-mRNA 3'-end processing machinery (2020, Science)
  • Integrator is a global promoter-proximal termination complex (2023, Molecular Cell)
  • Cryo-EM as a powerful tool for drug discovery (2020, Bioorganic & Medicinal Chemistry Letters)
  • Recent molecular insights into canonical pre-mRNA 3'-end processing (2020, Transcription)
  • Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs (2020, Nucleic Acids Research)

Frequent co-authors of Liang Tong include:

  • Yadong Sun
  • Zbigniew Domiński
  • Min-Han Lin
  • Wei Shen Aik
  • William F. Marzluff

The scientist has published extensively in several venues. The top publication venues for Liang Tong's work are:

  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Molecular Cell

In 2009, Liang Tong was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

    Michael V. Milburn;Liang Tong;Abraham M. deVos;Axel Brünger

  • Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.

    Christopher Pargellis;Liang Tong;Liang Tong;Laurie Churchill;Pier F. Cirillo

  • Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

    Yingwu Xu;Xiao Tao;Baohe Shen;Tiffany Horng

  • Protein production and purification.

    S Gräslund

  • Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

    A. M. De Vos;Liang Tong;M. V. Milburn;P. M. Matias

  • Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery.

    L. Tong

  • Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.

    Corey R. Mandel;Syuzo Kaneko;Hailong Zhang;Damara Gebauer;Damara Gebauer

  • Protein factors in pre-mRNA 3′-end processing

    Corey R. Mandel;Yun Bai;Liang Tong

  • A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket.

    Liang Tong;Susan Pav;Della M. White;Sheri Rogers

  • Structure and function of biotin-dependent carboxylases

    Liang Tong

  • Structural basis for self-association and receptor recognition of human TRAF2.

    Young Chul Park;Vicki Burkitt;Anthony R. Villa;Liang Tong

  • Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate.

    John Regan;Steffen Breitfelder;Pier Cirillo;Thomas Gilmore

  • Structural basis of the α1-β subunit interaction of voltage-gated Ca2+ channels

    Yu Hang Chen;Ming Hui Li;Yun Zhang;Lin Ling He

  • Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity

    Farhad Forouhar;Yue Yang;Dhirendra Kumar;Yang Chen

  • Crystal structure of dimeric HIV-1 capsid protein.

    Cory Momany;Ladislau C. Kovari;Andrew J. Prongay;Andrew J. Prongay;Walter Keller;Walter Keller

  • The locked rotation function.

    Liang Tong;M. G. Rossmann

  • Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion

    Hok-Kin Choi;Liang Tong;Wladek Minor;Philippe Dumas;Philippe Dumas

  • Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents

    Javed A Khan;Xiao Tao;Xiao Tao;Liang Tong

  • Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.

    Xiao Tao;Liang Tong

  • Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.

    Liang Tong;A. M. De Vos;M. V. Milburn;Sung-Hou Kim

  • Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

    L. Tong;C. Pargellis;L. Churchill;P. Cirillo

Frequent Co-Authors

Gaetano T. Montelione
Gaetano T. Montelione Rensselaer Polytechnic Institute
Rong Xiao
Rong Xiao Rutgers, The State University of New Jersey
Michael G. Rossmann
Michael G. Rossmann Purdue University West Lafayette
James L. Manley
James L. Manley Columbia University
Megerditch Kiledjian
Megerditch Kiledjian Rutgers, The State University of New Jersey
Sung-Hou Kim
Sung-Hou Kim University of California, Berkeley
John F. Hunt
John F. Hunt Columbia University
William F. Marzluff
William F. Marzluff University of North Carolina at Chapel Hill
Thomas Walz
Thomas Walz Rockefeller University
Hao Wu
Hao Wu Harvard University

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