World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
43913
World Ranking
1004
National Ranking
610

Research.com Recognitions

  • 2003 - Hellman Fellow

Overview

Thomas Walz is affiliated with Rockefeller University in the United States. Their research has primarily focused on the fields of biochemistry, genetics, and molecular biology, with secondary interests in medicine. Key subfields include molecular biology, physiology, radiology, nuclear medicine and imaging, immunology, and hematology.

Their work involves investigation into topics such as lipid membrane structure and behavior, monoclonal and polyclonal antibodies research, DNA repair mechanisms, erythrocyte function and pathophysiology, telomeres, telomerase, and senescence, platelet disorders and treatments, and genomics and chromatin dynamics.

Frequent co-authors in their publications include Yixiao Zhang, Titia de Lange, Barry S. Coller, Martin Bush, and Jihong Li.

Thomas Walz has published extensively in several scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Nature Communications
  • eLife
  • Proceedings of the National Academy of Sciences

Recent representative publications include:

  • A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms, 2020, Cell
  • Visualization of the mechanosensitive ion channel MscS under membrane tension, 2021, Nature
  • Structure of an active human histone pre-mRNA 3'-end processing machinery, 2020, Science
  • New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins, 2020, eLife
  • Pre-termination Transcription Complex: Structure and Function, 2020, Molecular Cell

Among the awards received, Thomas Walz was designated as a Hellman Fellow in 2003.

Best Publications

  • Structural determinants of water permeation through aquaporin-1.

    K Murata;K Mitsuoka;T Hirai;T Walz

  • Neurodegenerative disease: amyloid pores from pathogenic mutations.

    Hilal A. Lashuel;Dean Hartley;Benjamin M. Petre;Thomas Walz

  • Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

    Junichi Takagi;Benjamin M. Petre;Thomas Walz;Timothy A. Springer

  • The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

    Jixi Li;Thomas McQuade;Ansgar B. Siemer;Johanna Napetschnig

  • A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus

    Joseph D. Mougous;Marianne E. Cuff;Stefan Raunser;Aimee Shen

  • Latent TGF-β structure and activation

    Minlong Shi;Jianghai Zhu;Rui Wang;Xing Chen

  • STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

    Chan Young Park;Paul J. Hoover;Franklin M. Mullins;Priti Bachhawat

  • α-Synuclein, Especially the Parkinson's Disease-associated Mutants, Forms Pore-like Annular and Tubular Protofibrils

    Hilal A. Lashuel;Benjamin M. Petre;Joseph Wall;Martha Simon

  • Negative staining and image classification — powerful tools in modern electron microscopy

    Melanie Ohi;Ying Li;Yifan Cheng;Thomas Walz

  • Lipid-protein interactions in double-layered two-dimensional AQP0 crystals

    Tamir Gonen;Yifan Cheng;Piotr Sliz;Piotr Sliz;Yoko Hiroaki

  • Multiple Associated Proteins Regulate Proteasome Structure and Function

    David S. Leggett;John Hanna;Anna Borodovsky;Bernat Crosas

  • Structure of the human transferrin receptor-transferrin complex.

    Yifan Cheng;Olga Zak;Philip Aisen;Stephen C Harrison;Stephen C Harrison

  • Molecular model for a complete clathrin lattice from electron cryomicroscopy

    Alexander Fotin;Yifan Cheng;Piotr Sliz;Nikolaus Grigorieff

  • A primer to single-particle cryo-electron microscopy.

    Yifan Cheng;Nikolaus Grigorieff;Pawel A. Penczek;Thomas Walz

  • The three-dimensional structure of aquaporin-1

    Thomas Walz;Thomas Walz;Teruhisa Hirai;Kazuyoshi Murata;J. Bernard Heymann

  • Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5.

    Bin Wu;Alys Peisley;Alys Peisley;Claire Richards;Hui Yao

  • Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition

    Calvin K. Yip;Kazuyoshi Murata;Thomas Walz;Thomas Walz;David M. Sabatini

  • Implications of the aquaporin-4 structure on array formation and cell adhesion.

    Yoko Hiroaki;Kazutoshi Tani;Akiko Kamegawa;Nobuhiko Gyobu

  • Corrigendum: Lipid–protein interactions in double-layered two-dimensional AQP0 crystals

    Tamir Gonen;Yifan Cheng;Piotr Sliz;Yoko Hiroaki

  • A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein

    Joseph D. Mougous;Marianne E. Cuff;Stefan Raunser;Aimee Shen

Frequent Co-Authors

Yifan Cheng
Yifan Cheng University of California, San Francisco
Andreas Engel
Andreas Engel University of Basel
Timothy A. Springer
Timothy A. Springer Boston Children's Hospital
Stephen C. Harrison
Stephen C. Harrison Harvard University
Yoshinori Fujiyoshi
Yoshinori Fujiyoshi Nagoya University
Tamir Gonen
Tamir Gonen University of California, Los Angeles
Peter Agre
Peter Agre Johns Hopkins University
K. Christopher Garcia
K. Christopher Garcia Stanford University
Hilal A. Lashuel
Hilal A. Lashuel École Polytechnique Fédérale de Lausanne
Nikolaus Grigorieff
Nikolaus Grigorieff Howard Hughes Medical Institute

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