D-Index & Metrics Best Publications
Research.com 2023 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 113 Citations 50,313 569 World Ranking 192 National Ranking 120
Best female scientists D-index 123 Citations 56,511 741 World Ranking 293 National Ranking 185

Research.com Recognitions

Awards & Achievements

2023 - Research.com Best Female Scientist Award

2022 - Research.com Best Female Scientist Award

2015 - Member of the National Academy of Sciences

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Hao Wu spends much of her time researching Cell biology, Molecular biology, Signal transduction, Protein structure and Biochemistry. Her Cell biology research integrates issues from CARD Signaling Adaptor Proteins, Inflammasome and Innate immune system. Her Molecular biology research integrates issues from Cell culture, KDM1A, Supervillin, Caspase and Regulation of gene expression.

Her work carried out in the field of Caspase brings together such families of science as Inhibitor of apoptosis and In vivo. Her Signal transduction research includes elements of TRAF4, Receptor, MATH domain and TRAF2. Her research integrates issues of Peptide sequence and Death domain in her study of Protein structure.

Her most cited work include:

  • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. (1206 citations)
  • ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease (1043 citations)
  • Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores (1001 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Cell biology, Biochemistry, Inflammasome, Cancer research and Biophysics. Her Cell biology study integrates concerns from other disciplines, such as Caspase and Receptor, Innate immune system. Her Caspase study necessitates a more in-depth grasp of Programmed cell death.

A large part of her Biochemistry studies is devoted to Protein structure. Inflammasome is a subfield of Inflammation that Hao Wu studies. Her Cancer research research includes themes of Cancer and Metastasis.

She most often published in these fields:

  • Cell biology (49.78%)
  • Biochemistry (14.10%)
  • Inflammasome (17.99%)

What were the highlights of her more recent work (between 2019-2021)?

  • Cell biology (49.78%)
  • Inflammasome (17.99%)
  • Cancer research (10.94%)

In recent papers she was focusing on the following fields of study:

Hao Wu focuses on Cell biology, Inflammasome, Cancer research, Pyroptosis and Biophysics. The Cell biology study combines topics in areas such as In vitro, Cytosol, NSP1, Ternary complex and Translation. She studies Pyrin domain, a branch of Inflammasome.

Her study on Cancer research also encompasses disciplines like

  • Apoptosis which intersects with area such as Carcinogenesis,
  • Cytotoxic T cell together with Cancer cell. Hao Wu has included themes like Caspase and Immune system in her Pyroptosis study. Hao Wu usually deals with Biophysics and limits it to topics linked to Organelle and V-ATPase.

Between 2019 and 2021, her most popular works were:

  • Gasdermin E suppresses tumour growth by activating anti-tumour immunity. (156 citations)
  • Gasdermin E suppresses tumour growth by activating anti-tumour immunity. (156 citations)
  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution (110 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Her primary areas of investigation include Cell biology, Inflammasome, Inflammation, Pyroptosis and Biophysics. Her Cell biology research incorporates elements of Ternary complex, Untranslated region, Translation, Innate immune system and Ribosome. Her work is dedicated to discovering how Inflammasome, NLRP1 are connected with Signal transduction, Protein filament, Ankyrin, C-terminus and Active site and other disciplines.

The various areas that Hao Wu examines in her Inflammation study include HEK 293 cells, Bruton's tyrosine kinase, Disease and Cytokine. The concepts of her Pyroptosis study are interwoven with issues in Caspase, Immune system and Protein family. The study incorporates disciplines such as Bacterial outer membrane, Alpha helix, Organelle and Transmembrane protein in addition to Biophysics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu;Zhibin Zhang;Zhibin Zhang;Jianbin Ruan;Jianbin Ruan;Youdong Pan.
Nature (2016)

1705 Citations

DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation.

Keri Martinowich;Daisuke Hattori;Hao Wu;Shaun Fouse.
Science (2003)

1560 Citations

ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease

Joyce W. Lustbader;Maurizio Cirilli;Chang Lin;Hong Wei Xu;Hong Wei Xu.
Science (2004)

1472 Citations

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

Su Chang Lin;Yu Chih Lo;Hao Wu.
Nature (2010)

1060 Citations

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

Jixi Li;Thomas McQuade;Ansgar B. Siemer;Johanna Napetschnig.
Cell (2012)

1020 Citations

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

Hao Wu;Yi Zhang.
Cell (2014)

998 Citations

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

Hao Wu;Eduardo Esteve;Eduardo Esteve;Valentina Tremaroli;Muhammad Tanweer Khan.
Nature Medicine (2017)

986 Citations

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

Alvin Lu;Venkat Giri Magupalli;Venkat Giri Magupalli;Jianbin Ruan;Jianbin Ruan;Qian Yin;Qian Yin.
Cell (2014)

974 Citations

Molecular Basis of NF-κB Signaling

Johanna Napetschnig;Hao Wu.
Annual Review of Biophysics (2013)

877 Citations

Distinct molecular mechanism for initiating TRAF6 signalling.

Hong Ye;Joseph R. Arron;Joseph R. Arron;Betty Lamothe;Maurizio Cirilli.
Nature (2002)

751 Citations

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