D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 103 Citations 38,133 296 World Ranking 380 National Ranking 224

Research.com Recognitions

Awards & Achievements

2015 - Member of the National Academy of Sciences

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Hao Wu focuses on Cell biology, Signal transduction, Molecular biology, Biochemistry and Protein structure. His research investigates the connection between Cell biology and topics such as Innate immune system that intersect with issues in Acquired immune system. The concepts of his Signal transduction study are interwoven with issues in TRAF4, Receptor, MATH domain and TRAF2.

The various areas that Hao Wu examines in his Molecular biology study include Cell culture, Regulation of gene expression, KDM1A and Supervillin. As part of one scientific family, Hao Wu deals mainly with the area of Biochemistry, narrowing it down to issues related to the Biophysics, and often Short linear motif. His biological study spans a wide range of topics, including Peptide sequence, Protein subunit, Plasma protein binding and CARD Signaling Adaptor Proteins.

His most cited work include:

  • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. (1184 citations)
  • ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. (1006 citations)
  • Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores (839 citations)

What are the main themes of his work throughout his whole career to date?

Hao Wu mainly focuses on Cell biology, Biochemistry, Signal transduction, Biophysics and Caspase. His research integrates issues of Pyroptosis, Receptor, Inflammasome and Innate immune system in his study of Cell biology. His study in Inflammasome is interdisciplinary in nature, drawing from both Protein filament and Cytosol.

Hao Wu works in the field of Biochemistry, namely Protein structure. His research on Signal transduction frequently connects to adjacent areas such as Plasma protein binding. His Biophysics study frequently draws connections to other fields, such as Protein subunit.

He most often published in these fields:

  • Cell biology (53.34%)
  • Biochemistry (14.24%)
  • Signal transduction (15.44%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cell biology (53.34%)
  • Inflammasome (15.95%)
  • Biophysics (15.27%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Inflammasome, Biophysics, Pyroptosis and Cancer research. Hao Wu integrates many fields, such as Cell biology and Small nuclear RNA, in his works. His Inflammasome research is multidisciplinary, incorporating perspectives in Caspase, NLRP1 and Insulin resistance.

When carried out as part of a general Biophysics research project, his work on Cryo-electron microscopy is frequently linked to work in Mechanism, therefore connecting diverse disciplines of study. As part of the same scientific family, he usually focuses on Pyroptosis, concentrating on Immune system and intersecting with Effector. His work carried out in the field of Cancer research brings together such families of science as Apoptosis, Downregulation and upregulation, Ibrutinib, Cytotoxic T cell and Immunotherapy.

Between 2019 and 2021, his most popular works were:

  • Gasdermin E suppresses tumour growth by activating anti-tumour immunity. (89 citations)
  • Gasdermin E suppresses tumour growth by activating anti-tumour immunity. (89 citations)
  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Hao Wu mainly investigates Cell biology, Inflammasome, Pyroptosis, Caspase and Biophysics. His studies in Cell biology integrate themes in fields like Inflammation, RNA splicing, Epitope, Innate immune system and Methyltransferase. His biological study deals with issues like Insulin resistance, which deal with fields such as Microbiome and Gut flora.

His Pyroptosis study deals with Immune system intersecting with Effector, Cancer cell and Flow cytometry. His research in Caspase intersects with topics in Transport protein, Pyrin domain, Cytokine and Pharmacology. His studies deal with areas such as Mutant, NAD+ kinase, Enzyme, Peptide and Intramolecular force as well as Biophysics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation.

Keri Martinowich;Daisuke Hattori;Hao Wu;Shaun Fouse.
Science (2003)

1486 Citations

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

Joyce W. Lustbader;Maurizio Cirilli;Chang Lin;Hong Wei Xu;Hong Wei Xu.
Science (2004)

1367 Citations

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu;Zhibin Zhang;Zhibin Zhang;Jianbin Ruan;Jianbin Ruan;Youdong Pan.
Nature (2016)

1039 Citations

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

Su Chang Lin;Yu Chih Lo;Hao Wu.
Nature (2010)

946 Citations

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

Hao Wu;Yi Zhang.
Cell (2014)

883 Citations

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

Jixi Li;Thomas McQuade;Ansgar B. Siemer;Johanna Napetschnig.
Cell (2012)

847 Citations

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

Alvin Lu;Alvin Lu;Venkat Giri Magupalli;Venkat Giri Magupalli;Jianbin Ruan;Jianbin Ruan;Qian Yin;Qian Yin.
Cell (2014)

770 Citations

Molecular Basis of NF-κB Signaling

Johanna Napetschnig;Hao Wu.
Annual Review of Biophysics (2013)

758 Citations

Distinct molecular mechanism for initiating TRAF6 signalling.

Hong Ye;Joseph R. Arron;Joseph R. Arron;Betty Lamothe;Maurizio Cirilli.
Nature (2002)

713 Citations

All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

Jee Y. Chung;Young Chul Park;Hong Ye;Hao Wu.
Journal of Cell Science (2002)

704 Citations

Best Scientists Citing Hao Wu

Eicke Latz

Eicke Latz

University of Bonn

Publications: 74

Chuan He

Chuan He

University of Chicago

Publications: 68

John Silke

John Silke

Walter and Eliza Hall Institute of Medical Research

Publications: 60

Thirumala-Devi Kanneganti

Thirumala-Devi Kanneganti

St. Jude Children's Research Hospital

Publications: 58

James M. Murphy

James M. Murphy

Walter and Eliza Hall Institute of Medical Research

Publications: 52

Zhijian J. Chen

Zhijian J. Chen

The University of Texas Southwestern Medical Center

Publications: 49

Michael G. Rossmann

Michael G. Rossmann

Purdue University West Lafayette

Publications: 49

Colin R. Parrish

Colin R. Parrish

Cornell University

Publications: 46

Rudi Beyaert

Rudi Beyaert

Ghent University

Publications: 45

Guido Kroemer

Guido Kroemer

Sorbonne University

Publications: 44

Peter Vandenabeele

Peter Vandenabeele

Ghent University

Publications: 43

James E. Vince

James E. Vince

Walter and Eliza Hall Institute of Medical Research

Publications: 43

Guy S. Salvesen

Guy S. Salvesen

Discovery Institute

Publications: 42

Peng Jin

Peng Jin

Emory University

Publications: 42

Junying Yuan

Junying Yuan

Harvard University

Publications: 41

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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