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Rudi Beyaert

Rudi Beyaert

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Biology and Biochemistry
Belgium
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
110
Citations
53627
World Ranking
963
National Ranking
17

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Belgium Leader Award

Overview

Rudi Beyaert is affiliated with Ghent University in Belgium and has a research portfolio that spans immunology, molecular biology, oncology, and biochemistry. Their work primarily focuses on understanding immune system pathways and cancer biology.

Their main fields of study include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, subfields of interest consist of:

  • Immunology
  • Molecular Biology
  • Oncology
  • Cancer Research
  • Physiology

The main research topics they have explored cover:

  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Immune Response and Inflammation
  • NF-κB Signaling Pathways
  • Interferon and Immune Responses
  • Asthma and Respiratory Diseases
  • Cancer Immunotherapy and Biomarkers

Beyaert has published extensively in several scientific venues, with frequent publications appearing in:

  • FEBS Journal
  • Frontiers in Immunology
  • The Journal of Experimental Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemical Pharmacology

Collaborations have been an important part of their work. Frequent co-authors include:

  • Jens Staal
  • Yasmine Driege
  • Séamus J. Martin
  • Dublin Chair
  • Andrey Abramov

Recent papers authored by or involving Beyaert highlight a range of topics in cancer biology and immunology:

  • Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism, 2021, Gut
  • IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer, 2022, Cancer Cell
  • Polo-like kinase 1 (PLK1) signaling in cancer and beyond, 2021, Biochemical Pharmacology
  • Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome, 2020, The Journal of Experimental Medicine
  • Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases, 2020, Molecular Cell

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

    K Schulzeosthoff;Ac Bakker;Bart Vanhaesebroeck;Rudi Beyaert

  • More than one way to die: apoptosis, necrosis and reactive oxygen damage

    Walter Fiers;Rudi Beyaert;Wim Declercq;Peter Vandenabeele

  • Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor

    Dominique Vercammen;Rudi Beyaert;Geertrui Denecker;Vera Goossens

  • Two tumour necrosis factor receptors: structure and function.

    Peter Vandenabeele;Wim Declercq;Rudi Beyaert;Walter Fiers

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Role of Toll-Like Receptors in Pathogen Recognition

    Sophie Janssens;Rudi Beyaert

  • The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor.

    R. Beyaert;A. Cuenda;W. Vanden Berghe;S. Plaisance

  • Functional Diversity and Regulation of Different Interleukin-1 Receptor-Associated Kinase (IRAK) Family Members

    Sophie Janssens;Rudi Beyaert

  • Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

    K Schulzeosthoff;Rudi Beyaert;Veronique Vandevoorde;Guy Haegeman

  • Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

    Lianne van de Laar;Wouter Saelens;Sofie De Prijck;Liesbet Martens

  • Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome.

    Inna S Afonina;Zhenyu Zhong;Michael Karin;Rudi Beyaert

  • Inhibition of Interleukin 1 Receptor/Toll-like Receptor Signaling through the Alternatively Spliced, Short Form of MyD88 Is Due to Its Failure to Recruit IRAK-4

    Kimberly Burns;Sophie Janssens;Brian Brissoni;Natalia Olivos

  • Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

    Martijn J. Schuijs;Monique A. Willart;Karl Vergote;Delphine Gras

  • The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

    Lars Vereecke;Rudi Beyaert;Geert van Loo

  • Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

    Inna S. Afonina;Christina Müller;Seamus J. Martin;Rudi Beyaert

  • TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

    L. Verstrepen;T. Bekaert;Tieu-Lan Chau;J. Tavernier

  • Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

    Lieselotte Vande Walle;Nina Van Opdenbosch;Peggy Jacques;Amelie Fossoul

  • A universal role for MyD88 in TLR/IL-1R-mediated signaling.

    Sophie Janssens;Rudi Beyaert

  • T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20.

    Beatrice Coornaert;Mathijs Baens;Mathijs Baens;Karen Heyninck;Karen Heyninck;Tine Bekaert;Tine Bekaert

Frequent Co-Authors

Geert van Loo
Geert van Loo Ghent University
Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Walter Fiers
Walter Fiers Ghent University
Peter Vandenabeele
Peter Vandenabeele Ghent University
Sophie Janssens
Sophie Janssens Ghent University
Hamida Hammad
Hamida Hammad Ghent University
Dirk Elewaut
Dirk Elewaut Ghent University
Claude Libert
Claude Libert Ghent University
Jan Tavernier
Jan Tavernier Ghent University
Bart Vanhaesebroeck
Bart Vanhaesebroeck University College London

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