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Immunology
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2026

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Best Scientists

D-Index
179
Citations
114413
World Ranking
633
National Ranking
394

Immunology

D-Index
181
Citations
120983
World Ranking
34
National Ranking
23

Medicine

D-Index
181
Citations
121140
World Ranking
357
National Ranking
223

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2022 - Research.com Immunology in United States Leader Award
  • 2018 - Distinguished Service Award, Clinical Immunology Society
  • 2017 - AAI-Steinman Award for Human Immunology Research, American Association of Immunologists
  • 2015 - Member of the National Academy of Sciences
  • 2015 - Member of the National Academy of Medicine (NAM)
  • 2014 - Presidential Award, Clinical Immunology Society
  • 2014 - Robert Koch Prize
  • 2010 - E. Mead Johnson Award, Society for Pediatric Research
  • 2009 - Oswald Avery Award, Infectious Diseases Society of America
  • 2008 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for his contributions to the understanding the genetic basis of the predisposition to viral and bacterial diseases of childhood which have important clinical implications,,for the diagnostic and management of infectious diseases."
  • Member of the Association of American Physicians
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jean-Laurent Casanova is affiliated with Rockefeller University in the United States. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with a focus on Immunology, Infectious Diseases, Genetics, Molecular Biology, and Epidemiology.

The scientific topics most frequently addressed by their work include Immunodeficiency and Autoimmune Disorders, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Immune Cell Function and Interaction, interferon and immune responses, Blood disorders and treatments, and T-cell and B-cell Immunology.

Their recent notable papers are:

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19, 2020, Science
  • Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee, 2020, Journal of Clinical Immunology
  • Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study, 2020, BMJ
  • Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification, 2020, Journal of Clinical Immunology
  • Human genetic and immunological determinants of critical COVID-19 pneumonia, 2022, Nature

Frequent co-authors in their publications include:

  • Laurent Abel
  • Paul Bastard
  • Anne Puel
  • Jacinta Bustamante
  • Shen-Ying Zhang

They have published extensively in several scientific venues, most notably the Journal of Clinical Immunology, The Journal of Experimental Medicine, bioRxiv (Cold Spring Harbor Laboratory), Journal of Human Immunity, and the Journal of Clinical Investigation.

Awards and honors received by Jean-Laurent Casanova include the Distinguished Service Award from the Clinical Immunology Society in 2018, the AAI-Steinman Award for Human Immunology Research from the American Association of Immunologists in 2017, membership in the National Academy of Sciences and the National Academy of Medicine both in 2015, and the Robert Koch Prize in 2014.

Additional recognitions include the Presidential Award from the Clinical Immunology Society (2014), the E. Mead Johnson Award from the Society for Pediatric Research (2010), the Oswald Avery Award from the Infectious Diseases Society of America (2009), the Richard Lounsbery Award from the National Academy of Sciences and the French Academy of Sciences (2008), as well as memberships in the Association of American Physicians and the European Molecular Biology Organization (EMBO).

Best Publications

  • Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

    Marina Cavazzana-Calvo;Salima Hacein-Bey;Geneviève De Saint Basile;Fabian Gross

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.

    Robert S. Wildin;Fred Ramsdell;Jane Peake;Francesca Faravelli

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors.

    Jérôme Cros;Nicolas Cagnard;Kevin Woollard;Natacha Patey

  • TLR3 deficiency in patients with herpes simplex encephalitis.

    Shen Ying Zhang;Shen Ying Zhang;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Sophie Ugolini;Asma Smahi

  • Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

    Horst Von Bernuth;Capucine Picard;Capucine Picard;Zhongbo Jin;Rungnapa Pankla;Rungnapa Pankla

  • GENETIC DISSECTION OF IMMUNITY TO MYCOBACTERIA: THE HUMAN MODEL

    Jean-Laurent Casanova;Laurent Abel

  • Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity

    Anne Puel;Sophie Cypowyj;Jacinta Bustamante;Jill Wright

  • Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study.

    Julie Toubiana;Julie Toubiana;Clément Poirault;Alice Corsia;Fanny Bajolle

  • INTERFERON-GAMMA-RECEPTOR DEFICIENCY IN AN INFANT WITH FATAL BACILLE CALMETTE-GUERIN INFECTION

    Emmanuelle Jouanguy;Frédéric Altare;Salma Lamhamedi;Patrick Revy

  • Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

    Slaheddine Marrakchi;Philippe Guigue;Blair R. Renshaw;Anne Puel

  • Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency

    Frédéric Altare;Anne Durandy;David Lammas;Jean-François Emile

  • Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients

    Rolien de Jong;Frédéric Altare;Inez-Anne Haagen;Diënne G. Elferink

  • Human blood IgM “memory” B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

    Sandra Weller;Moritz C. Braun;Bruce K. Tan;Andreas Rosenwald

  • X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.

    Rainer Döffinger;Asma Smahi;Christine Bessia;Frédéric Geissmann

  • Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency.

    Stéphanie Dupuis;Emmanuelle Jouanguy;Sami Al-Hajjar;Claire Fieschi

  • IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

    Michele W L Teng;Edward P Bowman;Joshua J McElwee;Mark J Smyth

  • Herpes simplex virus encephalitis in human UNC-93B deficiency.

    Armanda Casrouge;Shen Ying Zhang;Shen Ying Zhang;Céline Eidenschenk;Emmanuelle Jouanguy;Emmanuelle Jouanguy

  • International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity

    Capucine Picard;H. Bobby Gaspar;Waleed Al-Herz;Aziz Bousfiha

  • Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015

    Capucine Picard;Waleed Al-Herz;Aziz Bousfiha;Jean Laurent Casanova

Frequent Co-Authors

Laurent Abel
Laurent Abel Université Paris Cité
Jacinta Bustamante
Jacinta Bustamante Rockefeller University
Capucine Picard
Capucine Picard Université Paris Cité
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Shen-Ying Zhang
Shen-Ying Zhang Rockefeller University
Bertrand Boisson
Bertrand Boisson Rockefeller University
Alain Fischer
Alain Fischer Collège de France
Aurélie Cobat
Aurélie Cobat Grenoble Alpes University

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