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Immunology

D-Index
84
Citations
29459
World Ranking
1350
National Ranking
50

Medicine

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84
Citations
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World Ranking
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National Ranking
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Overview

Emmanuelle Jouanguy is affiliated with Necker-Enfants Malades Hospital in France. Their research primarily focuses on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these main fields, their work spans subfields such as Immunology, Infectious Diseases, Genetics, Epidemiology, and Molecular Biology.

Their scholarly output encompasses topics including Immunodeficiency and Autoimmune Disorders, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Parvovirus B19 Infection Studies, interferon and immune responses, Immune Cell Function and Interaction, and Blood disorders and treatments.

Emmanuelle Jouanguy has published research in several prominent journals. Frequent publication venues include:

  • The Journal of Experimental Medicine
  • Journal of Clinical Immunology
  • Journal of Investigative Dermatology
  • Journal of Clinical Investigation
  • Current Opinion in Immunology

Some of their notable recent papers consist of:

  • "Autoantibodies against type I IFNs in patients with life-threatening COVID-19", 2020, Science
  • "Human genetic and immunological determinants of critical COVID-19 pneumonia", 2022, Nature
  • "Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1", 2021, The Journal of Experimental Medicine
  • "A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection", 2020, Cell
  • "Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine", 2021, The Journal of Experimental Medicine

Their frequent collaborators include Jean-Laurent Casanova, Paul Bastard, Laurent Abel, Vivien Béziat, and Anne Puel. This network of coauthors indicates a focus on immunological genetics and infectious disease research.

Best Publications

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • TLR3 deficiency in patients with herpes simplex encephalitis.

    Shen Ying Zhang;Shen Ying Zhang;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Sophie Ugolini;Asma Smahi

  • INTERFERON-GAMMA-RECEPTOR DEFICIENCY IN AN INFANT WITH FATAL BACILLE CALMETTE-GUERIN INFECTION

    Emmanuelle Jouanguy;Frédéric Altare;Salma Lamhamedi;Patrick Revy

  • Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency

    Frédéric Altare;Anne Durandy;David Lammas;Jean-François Emile

  • Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency.

    Stéphanie Dupuis;Emmanuelle Jouanguy;Sami Al-Hajjar;Claire Fieschi

  • Herpes simplex virus encephalitis in human UNC-93B deficiency.

    Armanda Casrouge;Shen Ying Zhang;Shen Ying Zhang;Céline Eidenschenk;Emmanuelle Jouanguy;Emmanuelle Jouanguy

  • Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

    Luyan Liu;Satoshi Okada;Xiao Fei Kong;Alexandra Y. Kreins

  • The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila.

    Catherine Dostert;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Phil Irving;Laurent Troxler

  • A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection

    Emmanuelle Jouanguy;Salma Lamhamedi-Cherradi;David Lammas;Susan E. Dorman

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

    Xianqin Zhang;Dusan Bogunovic;Béatrice Payelle-Brogard;Véronique Francois-Newton

  • Human genetic and immunological determinants of critical COVID-19 pneumonia

    Unknown

  • Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: molecular, cellular, and clinical features.

    Orchidée Filipe-Santos;Jacinta Bustamante;Ariane Chapgier;Guillaume Vogt

  • Toll-related receptors and the control of antimicrobial peptide expression in Drosophila.

    Servane Tauszig;Emmanuelle Jouanguy;Jules A. Hoffmann;Jean-Luc Imler

  • Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection.

    F Altare;D Lammas;P Revy;E Jouanguy

  • IL-12 and IFN-gamma in host defense against mycobacteria and salmonella in mice and men.

    Emmanuelle Jouanguy;Rainer Döffinger;Stéphanie Dupuis;Annaïck Pallier

  • Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guérin infection and a sibling with clinical tuberculosis.

    E Jouanguy;S Lamhamedi-Cherradi;F Altare;M C Fondanèche

  • Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense.

    Shen-Ying Zhang;Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Ariane Chapgier;Ariane Chapgier;Kun Yang;Kun Yang

  • Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis

    Rebeca Pérez de Diego;Rebeca Pérez de Diego;Rebeca Pérez de Diego;Vanessa Sancho-Shimizu;Vanessa Sancho-Shimizu;Vanessa Sancho-Shimizu;Lazaro Lorenzo;Lazaro Lorenzo;Lazaro Lorenzo;Anne Puel;Anne Puel;Anne Puel

  • Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

    Fabien G Lafaille;Itai M. Pessach;Itai M. Pessach;Shen-Ying Zhang;Shen-Ying Zhang;Michael J. Ciancanelli

  • Human TLR-7-, -8-, and -9-Mediated Induction of IFN-α/β and -λ Is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses

    Kun Yang;Kun Yang;Anne Puel;Shenying Zhang;Shenying Zhang;Céline Eidenschenk

Frequent Co-Authors

Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Laurent Abel
Laurent Abel Université Paris Cité
Shen-Ying Zhang
Shen-Ying Zhang Rockefeller University
Capucine Picard
Capucine Picard Université Paris Cité
Jacinta Bustamante
Jacinta Bustamante Rockefeller University
Aurélie Cobat
Aurélie Cobat Grenoble Alpes University
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Alain Fischer
Alain Fischer Collège de France

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