D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 50 Citations 8,459 124 World Ranking 3377 National Ranking 155

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Dopamine
  • Neurotransmitter

The scientist’s investigation covers issues in Neuroscience, Dopamine receptor D2, Dopamine, Endocrinology and Internal medicine. The various areas that Alessandro Usiello examines in his Neuroscience study include Synaptic plasticity, NMDA receptor, Levodopa, Dyskinesia and Long-term depression. His work in NMDA receptor addresses subjects such as Prepulse inhibition, which are connected to disciplines such as Glutamate receptor.

His Dopamine receptor D2 research is classified as research in Receptor. His Receptor research incorporates elements of Dopaminergic and Pharmacology. He has included themes like Adenosine A2A receptor, Cannabinoid and Phosphorylation, Cell biology in his Endocrinology study.

His most cited work include:

  • Distinct functions of the two isoforms of dopamine D2 receptors (590 citations)
  • Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in l-DOPA-Induced Dyskinesia (359 citations)
  • Caffeine as a psychomotor stimulant: mechanism of action. (351 citations)

What are the main themes of his work throughout his whole career to date?

Alessandro Usiello mainly focuses on Neuroscience, Internal medicine, Endocrinology, Dopamine and NMDA receptor. His Neuroscience research is multidisciplinary, incorporating perspectives in Synaptic plasticity, Glutamate receptor and Long-term potentiation. His Internal medicine course of study focuses on Phosphorylation and Kinase.

His study on Dopamine is mostly dedicated to connecting different topics, such as Pharmacology. His study in NMDA receptor is interdisciplinary in nature, drawing from both Prepulse inhibition, Glutamatergic and Hippocampus. Alessandro Usiello interconnects Dopamine receptor and Cell biology in the investigation of issues within Dopamine receptor D2.

He most often published in these fields:

  • Neuroscience (50.00%)
  • Internal medicine (33.08%)
  • Endocrinology (33.08%)

What were the highlights of his more recent work (between 2018-2021)?

  • Dopamine (26.92%)
  • Neuroscience (50.00%)
  • Striatum (19.23%)

In recent papers he was focusing on the following fields of study:

Alessandro Usiello mainly investigates Dopamine, Neuroscience, Striatum, NMDA receptor and Endocrinology. His work investigates the relationship between Dopamine and topics such as Pharmacology that intersect with problems in Abnormal involuntary movement and Dyskinesia. His studies deal with areas such as Multiple sclerosis, Neurotransmission and G protein-coupled inwardly-rectifying potassium channel as well as Neuroscience.

His Striatum research includes elements of Dopaminergic, PI3K/AKT/mTOR pathway and Pars compacta. The study incorporates disciplines such as Synaptic plasticity and Cell biology in addition to NMDA receptor. His studies in Endocrinology integrate themes in fields like Oxidase test and Internal medicine, Cerebrospinal fluid.

Between 2018 and 2021, his most popular works were:

  • The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients (15 citations)
  • Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity. (13 citations)
  • RasGRP1 is a causal factor in the development of l-DOPA–induced dyskinesia in Parkinson’s disease (12 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Dopamine
  • Enzyme

Alessandro Usiello spends much of his time researching Internal medicine, Substantia nigra, Endocrinology, Cell biology and D-aspartate oxidase. Alessandro Usiello studies Dopamine which is a part of Internal medicine. His Dopamine study combines topics in areas such as Agonist and Putamen.

His Cell biology research integrates issues from Epigenetics and Gene. Alessandro Usiello combines subjects such as Extracellular, Neural development and Catabolism with his study of D-aspartate oxidase. His NMDA receptor research includes themes of Synaptic plasticity, Oxidase test, Cerebral cortex and Hippocampus.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Distinct functions of the two isoforms of dopamine D2 receptors

Alessandro Usiello;Ja Hyun Baik;Françoise Rougé-Pont;Roberto Picetti.
Nature (2000)

844 Citations

Caffeine as a psychomotor stimulant: mechanism of action

G. Fisone;A. Borgkvist;A. Usiello.
Cellular and Molecular Life Sciences (2004)

643 Citations

Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in l-DOPA-Induced Dyskinesia

Emanuela Santini;Emmanuel Valjent;Alessandro Usiello;Manolo Carta.
The Journal of Neuroscience (2007)

460 Citations

Receptor Subtypes Involved in the Presynaptic and Postsynaptic Actions of Dopamine on Striatal Interneurons

Diego Centonze;Cristina Grande;Alessandro Usiello;Paolo Gubellini.
The Journal of Neuroscience (2003)

260 Citations

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain.

Eduardo Puelles;Alessandro Annino;Francesca Tuorto;Alessandro Usiello.
Development (2004)

246 Citations

Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites

Niklas Lindgren;Alessandro Usiello;Michel Goiny;John Haycock.
Proceedings of the National Academy of Sciences of the United States of America (2003)

245 Citations

Changes in Extracellular Dopamine Induced by Morphine and Cocaine: Crucial Control by D2 Receptors

Françoise Rougé-Pont;Alessandro Usiello;Marianne Benoit-Marand;François Gonon.
The Journal of Neuroscience (2002)

214 Citations

Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia

M Lundblad;A Usiello;Manolo Carta;K Hakansson.
Experimental Neurology (2005)

212 Citations

Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

F. Guida;F. Turco;M. Iannotta;D. De Gregorio.
Brain Behavior and Immunity (2018)

208 Citations

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine

Giuseppina Martella;Annalisa Tassone;Giuseppe Sciamanna;Paola Platania.
Brain (2009)

193 Citations

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