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Neuroscience

D-Index
57
Citations
10768
World Ranking
4366
National Ranking
200

Overview

Alessandro Usiello is affiliated with the University of Campania "Luigi Vanvitelli" in Italy. Their research focuses on a range of topics spanning biochemistry, molecular biology, neuroscience, and medicine.

The scientist has produced work in multiple fields of study, including:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Subfields of particular focus include:

  • Molecular Biology
  • Biochemistry
  • Cellular and Molecular Neuroscience
  • Neurology
  • Clinical Biochemistry

Usiello's research addresses several main topics, such as:

  • Amino Acid Enzymes and Metabolism
  • Neuroscience and Neuropharmacology Research
  • Metabolism and Genetic Disorders
  • Epigenetics and DNA Methylation
  • Parkinson's Disease Mechanisms and Treatments
  • Diet and metabolism studies
  • Neurogenetic and Muscular Disorders Research

The scientist's published papers include:

  • New Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications (2020, International Journal of Molecular Sciences)
  • RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease (2020, Science Advances)
  • Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain (2022, Schizophrenia)
  • New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life (2020, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics)
  • High performance liquid chromatography determination of l-glutamate, l-glutamine and glycine content in brain, cerebrospinal fluid and blood serum of patients affected by Alzheimer's disease (2021, Amino Acids)

Frequent coauthors of Usiello include:

  • Francesco Errico
  • Tommaso Nuzzo
  • Anna Maio
  • Arianna De Rosa
  • Isar Yahyavi

Their work often appears in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurobiology of Disease
  • International Journal of Molecular Sciences
  • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  • Journal of Neurochemistry

Best Publications

  • Distinct functions of the two isoforms of dopamine D2 receptors

    Alessandro Usiello;Ja Hyun Baik;Françoise Rougé-Pont;Roberto Picetti

  • Caffeine as a psychomotor stimulant: mechanism of action

    G. Fisone;A. Borgkvist;A. Usiello

  • Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in l-DOPA-Induced Dyskinesia

    Emanuela Santini;Emmanuel Valjent;Alessandro Usiello;Manolo Carta

  • Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

    F. Guida;F. Turco;M. Iannotta;D. De Gregorio

  • Receptor Subtypes Involved in the Presynaptic and Postsynaptic Actions of Dopamine on Striatal Interneurons

    Diego Centonze;Cristina Grande;Alessandro Usiello;Paolo Gubellini

  • Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites

    Niklas Lindgren;Alessandro Usiello;Michel Goiny;John Haycock

  • Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain.

    Eduardo Puelles;Alessandro Annino;Francesca Tuorto;Alessandro Usiello

  • Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia

    M Lundblad;A Usiello;Manolo Carta;K Hakansson

  • Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine

    Giuseppina Martella;Annalisa Tassone;Giuseppe Sciamanna;Paola Platania

  • Changes in Extracellular Dopamine Induced by Morphine and Cocaine: Crucial Control by D2 Receptors

    Françoise Rougé-Pont;Alessandro Usiello;Marianne Benoit-Marand;François Gonon

  • Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes

    Angela Nebbioso;Fabio Manzo;Marco Miceli;Mariarosaria Conte

  • Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum.

    Laura Pozzi;Kerstin Håkansson;Alessandro Usiello;Anders Borgkvist

  • Chronic Psychoemotional Stress Impairs Cannabinoid-Receptor-Mediated Control of GABA Transmission in the Striatum

    S. Rossi;V. De Chiara;A. Musella;H. Kusayanagi

  • d-Aspartate Prevents Corticostriatal Long-Term Depression and Attenuates Schizophrenia-Like Symptoms Induced by Amphetamine and MK-801

    Francesco Errico;Silvia Rossi;Francesco Napolitano;Valeria Catuogno

  • Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.

    F. Guida;L. Luongo;F. Marmo;R. Romano

  • The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation

    Francesca Gabanella;Claudia Carissimi;Alessandro Usiello;Livio Pellizzoni

  • Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons.

    Mikael Andersson;Alessandro Usiello;Anders Borgkvist;Laura Pozzi

  • Differential contribution of dopamine D2S and D2L receptors in the modulation of glutamate and GABA transmission in the striatum.

    D. Centonze;P. Gubellini;A. Usiello;S. Rossi

  • Interleukin-1β causes anxiety by interacting with the endocannabinoid system.

    Silvia Rossi;Lucia Sacchetti;Francesco Napolitano;Valentina De Chiara

  • N-methyl-D-aspartate and dopamine receptor involvement in the modulation of locomotor activity and memory processes.

    W. Adriani;A. Felici;F. Sargolini;P. Roullet

  • Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.

    Srinivasa Subramaniam;Francesco Napolitano;Robert G Mealer;Seyun Kim;Seyun Kim

Frequent Co-Authors

Massimo Pasqualetti
Massimo Pasqualetti University of Pisa
Diego Centonze
Diego Centonze University of Rome Tor Vergata
Giorgio Bernardi
Giorgio Bernardi University of Rome Tor Vergata
Gilberto Fisone
Gilberto Fisone Karolinska Institute
Alessandro Bertolino
Alessandro Bertolino University of Bari Aldo Moro
Nicola B. Mercuri
Nicola B. Mercuri University of Rome Tor Vergata
Paolo Calabresi
Paolo Calabresi Catholic University of the Sacred Heart
Robert Nisticò
Robert Nisticò University of Rome Tor Vergata
Silvia Rossi
Silvia Rossi Chiesi (Italy)
Alessandra Musella
Alessandra Musella Università Telematica San Raffaele Roma

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