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Molecular Biology

D-Index
49
Citations
10700
World Ranking
2617
National Ranking
1280

Overview

Eric E. Bouhassira is affiliated with the Albert Einstein College of Medicine in the United States. Their research spans primarily the fields of medicine and biochemistry, genetics, and molecular biology, with a focus on genetics, molecular biology, hematology, cancer research, and physiology.

The scientist's work addresses multiple main topics including hemoglobinopathies and related disorders, epigenetics and DNA methylation, erythrocyte function and pathophysiology, cancer-related molecular mechanisms, blood groups and transfusion, genetic syndromes and imprinting, and acute myeloid leukemia research.

Some of the recent papers authored or co-authored by Eric E. Bouhassira include:

  • Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial, 2022, published in Nature Medicine
  • Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites, 2021, published in Proceedings of the National Academy of Sciences
  • Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability, 2022, published in Nature Communications
  • Characterization of Hematopoiesis in Sickle Cell Disease by Prospective Isolation of Stem and Progenitor Cells, 2020, published in Cells
  • Hemoglobin F mitigation of sickle cell complications decreases with aging, 2020, published in American Journal of Hematology

Frequent collaborators in their work include Zi Yan, Shouping Zhang, Emmanuel Olivier, Seda S. Tolu, and Kai Wang. Collaboration counts range from four to ten publications with these co-authors.

Eric E. Bouhassira has published multiple articles in notable scientific journals and venues such as Blood, Cells, Haematologica, bioRxiv (Cold Spring Harbor Laboratory), and UNC Libraries.

Best Publications

  • Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

    Gallia G. Levy;William C. Nichols;Eric C. Lian;Tatiana Foroud

  • Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy

    Robert Pawliuk;Karen A. Westerman;Mary E. Fabry;Emmanuel Payen

  • Histone H1 Depletion in Mammals Alters Global Chromatin Structure but Causes Specific Changes in Gene Regulation

    Yuhong Fan;Tatiana Nikitina;Jie Zhao;Tomara J. Fleury

  • Polymerase chain reaction amplification applied to the determination of β‐like globin gene cluster haplotypes

    Millicent Sutton;Eric E. Bouhassira;Ronald L. Nagel;Ronald L. Nagel

  • Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange.

    Yong Qing Feng;Jost Seibler;Raouf Alami;Andrew Eisen

  • Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells

    Emmanuel N. Olivier;Anne C. Rybicki;Eric E. Bouhassira

  • Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

    Dirk Schübeler;Matthew C. Lorincz;Daniel M. Cimbora;Agnes Telling

  • Permanent and panerythroid correction of murine β thalassemia by multiple lentiviral integration in hematopoietic stem cells

    Suzan Imren;Emmanuel Payen;Karen A. Westerman;Robert Pawliuk

  • Transcriptional Interference by Independently Regulated Genes Occurs in Any Relative Arrangement of the Genes and Is Influenced by Chromosomal Integration Position

    Susan K. Eszterhas;Eric E. Bouhassira;David I. K. Martin;Steven Fiering

  • Transferrin therapy ameliorates disease in beta-thalassemic mice.

    Huihui Li;Anne C Rybicki;Sandra M Suzuka;Leni von Bonsdorff

  • ADAMTS13 is expressed in hepatic stellate cells.

    Wenhua Zhou;Mari Inada;Mari Inada;Tai Ping Lee;Tai Ping Lee;Daniel Benten

  • Transcriptional Behavior of LCR Enhancer Elements Integrated at the Same Chromosomal Locus by Recombinase-Mediated Cassette Exchange

    Eric E. Bouhassira;Karen Westerman;Karen Westerman;Karen Westerman;Philippe Leboulch;Philippe Leboulch;Philippe Leboulch

  • Large-scale production of embryonic red blood cells from human embryonic stem cells.

    Emmanuel N. Olivier;Caihong Qiu;Michelle Velho;Rhoda Elison Hirsch

  • Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells.

    Caihong Qiu;Emmanuel N. Olivier;Michelle Velho;Eric E. Bouhassira

  • High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers

    Mayumi Oda;Mayumi Oda;Jacob L. Glass;Reid F. Thompson;Yongkai Mo

  • Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development.

    Caihong Qiu;Eric Hanson;Emmanuel Olivier;Mari Inada

  • Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery

    Enko N. Kiprilov;Aashir Awan;Romain Desprat;Michelle Velho

  • Mammalian linker-histone subtypes differentially affect gene expression in vivo

    Raouf Alami;Yuhong Fan;Stephanie Pack;Timothy M. Sonbuchner

  • Autophagy Driven by a Master Regulator of Hematopoiesis

    Yoon A. Kang;Rajendran Sanalkumar;Henriette O'geen;Amelia K. Linnemann

  • Biologic properties and enucleation of red blood cells from human embryonic stem cells. Commentary

    Eric E. Bouhassira;Shi-Jiang Lu;Qiang Feng;Jennifer S. Park

Frequent Co-Authors

Ronald L. Nagel
Ronald L. Nagel Albert Einstein College of Medicine
Mirit I. Aladjem
Mirit I. Aladjem National Institutes of Health
Philippe Leboulch
Philippe Leboulch Brigham and Women's Hospital
Mark Groudine
Mark Groudine Fred Hutchinson Cancer Research Center
John M. Greally
John M. Greally Albert Einstein College of Medicine
David Ginsburg
David Ginsburg University of Michigan–Ann Arbor
Connie J. Eaves
Connie J. Eaves University of British Columbia
Christoph Bock
Christoph Bock Austrian Academy of Sciences
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Marc Lalande
Marc Lalande University of Connecticut Health Center

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