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Immunology

D-Index
44
Citations
12100
World Ranking
4746
National Ranking
180

Overview

Koichi Yanaba is affiliated with the Jikei University School of Medicine in Japan. Their research spans several areas within medicine, with a focus on immunology, dermatology, and pathology. Yanaba has contributed to fields including systemic sclerosis, autoimmune skin diseases, mast cells and histamine, and inflammatory myopathies.

The main fields of study for Yanaba include:

  • Medicine
  • Immunology and Microbiology

Subfields covered in their work include:

  • Pathology and Forensic Medicine
  • Immunology
  • Rehabilitation
  • Dermatology
  • Epidemiology

Key topics in Yanaba's research are:

  • Systemic Sclerosis and Related Diseases
  • Autoimmune Bullous Skin Diseases
  • Mast cells and histamine
  • Exercise and Physiological Responses
  • Toxin Mechanisms and Immunotoxins
  • Dermatology and Skin Diseases
  • Inflammatory Myopathies and Dermatomyositis

Yanaba has authored several recent papers, such as:

  • "Perspective to precision medicine in scleroderma," published in 2024 in Frontiers in Immunology
  • "Inhibitory role of interleukin-10 in the cutaneous reverse Arthus reaction," published in 2020 in The Journal of Dermatology
  • "Adult-onset generalized morphea associated with osteomyelitis," published in 2020 in The Journal of Dermatology

The scientific collaborations of Yanaba include working frequently with:

  • Kazuhiro Komura
  • Jean-David Bouaziz
  • Ayumi Yoshizaki
  • Minoru Hasegawa
  • John Varga

The main venues where Yanaba's research appears are:

  • The Journal of Dermatology
  • Frontiers in Immunology

Best Publications

  • A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

    Koichi Yanaba;Jean-David Bouaziz;Karen M. Haas;Jonathan C. Poe

  • Characterization of a rare IL-10–competent B-cell subset in humans that parallels mouse regulatory B10 cells

    Yohei Iwata;Takashi Matsushita;Mayuka Horikawa;David J. DiLillo

  • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

    Takashi Matsushita;Koichi Yanaba;Jean-David Bouaziz;Manabu Fujimoto

  • The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

    Koichi Yanaba;Jean-David Bouaziz;Takashi Matsushita;Takeshi Tsubata

  • Regulatory B cells as inhibitors of immune responses and inflammation.

    Jean-David Bouaziz;Koichi Yanaba;Thomas F. Tedder

  • B-lymphocyte contributions to human autoimmune disease.

    Koichi Yanaba;Jean-David Bouaziz;Takashi Matsushita;Cynthia M. Magro

  • B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice

    David J. DiLillo;Koichi Yanaba;Thomas F. Tedder

  • Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

    Jean David Bouaziz;Koichi Yanaba;Guglielmo M. Venturi;Yaming Wang

  • Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy

    K. Kaji;M. Fujimoto;M. Hasegawa;M. Kondo

  • Elevated serum BAFF levels in patients with systemic sclerosis: Enhanced BAFF signaling in systemic sclerosis B lymphocytes

    Takashi Matsushita;Minoru Hasegawa;Koichi Yanaba;Masanari Kodera

  • B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis.

    Minoru Hasegawa;Yasuhito Hamaguchi;Koichi Yanaba;Jean-David Bouaziz

  • IL-10-producing regulatory B10 cells inhibit intestinal injury in a mouse model.

    Koichi Yanaba;Ayumi Yoshizaki;Yoshihide Asano;Takafumi Kadono

  • B Cell Depletion Delays Collagen-Induced Arthritis in Mice: Arthritis Induction Requires Synergy between Humoral and Cell-Mediated Immunity

    Koichi Yanaba;Yasuhito Hamaguchi;Guglielmo M. Venturi;Douglas A. Steeber

  • Cell Adhesion Molecules Regulate Fibrotic Process via Th1/Th2/Th17 Cell Balance in a Bleomycin-Induced Scleroderma Model

    Ayumi Yoshizaki;Koichi Yanaba;Yohei Iwata;Kazuhiro Komura

  • Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis

    Koichi Yanaba;Ayumi Yoshizaki;Yoshihide Asano;Takafumi Kadono

  • Comparative study of serum surfactant protein-D and KL-6 concentrations in patients with systemic sclerosis as markers for monitoring the activity of pulmonary fibrosis.

    Koichi Yanaba;Minoru Hasegawa;Kazuhiko Takehara;Shinichi Sato

  • Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis

    Ayumi Yoshizaki;Koichi Yanaba;Asako Yoshizaki;Yohei Iwata

  • Serum pulmonary and activation-regulated chemokine/CCL18 levels in patients with systemic sclerosis: a sensitive indicator of active pulmonary fibrosis.

    Masanari Kodera;Minoru Hasegawa;Kazuhiro Komura;Koichi Yanaba

  • Serum soluble CTLA-4 levels are increased in diffuse cutaneous systemic sclerosis

    S Sato;M Fujimoto;M Hasegawa;K Komura

  • Immunization with DNA topoisomerase I and Freund's complete adjuvant induces skin and lung fibrosis and autoimmunity via interleukin-6 signaling.

    Ayumi Yoshizaki;Koichi Yanaba;Asako Ogawa;Yoshihide Asano

  • Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation

    Koichi Yanaba;Masahiro Kamata;Nobuko Ishiura;Sayaka Shibata

Frequent Co-Authors

Shinichi Sato
Shinichi Sato University of Tokyo
Yoshihide Asano
Yoshihide Asano University of Tokyo
Takafumi Kadono
Takafumi Kadono St. Marianna University School of Medicine
Minoru Hasegawa
Minoru Hasegawa University of Fukui
Thomas F. Tedder
Thomas F. Tedder Duke University
Manabu Fujimoto
Manabu Fujimoto Osaka University
Kazuhiko Takehara
Kazuhiko Takehara Kanazawa University
Hidehisa Saeki
Hidehisa Saeki Nippon Medical School
Douglas A. Steeber
Douglas A. Steeber University of Wisconsin–Milwaukee
Takashi Taniguchi
Takashi Taniguchi National Institute for Materials Science

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