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Yoshihide Asano

Yoshihide Asano

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
15086
World Ranking
6771
National Ranking
451

Medicine

D-Index
71
Citations
15626
World Ranking
20023
National Ranking
641

Overview

Yoshihide Asano is affiliated with the University of Tokyo in Japan and specializes in medicine, with a focus on pathology and forensic medicine, dermatology, immunology, oncology, and epidemiology. Their research addresses various aspects of systemic sclerosis and related diseases, contributing to a deeper understanding of autoimmune and inflammatory conditions.

Their recent publications include studies on systemic sclerosis and immune-mediated disorders, such as:

  • "Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial" (2020) published in The Lancet Respiratory Medicine
  • "Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial" (2021) published in The Lancet Rheumatology
  • "The Pathogenesis of Systemic Sclerosis: An Understanding Based on a Common Pathologic Cascade across Multiple Organs and Additional Organ-Specific Pathologies" (2020) published in Journal of Clinical Medicine
  • "Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis" (2021) published in Nature Communications
  • "Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis" (2022) published in Science Immunology

Asano frequently co-authors work with several researchers including:

  • Shinichi Sato
  • Taku Fujimura
  • Yumi Kambayashi
  • Ayumi Yoshizaki
  • Ryo Amagai

Their publications appear predominantly in journals such as:

  • The Journal of Dermatology
  • European Journal of Dermatology
  • Case Reports in Oncology
  • Journal of Clinical Medicine
  • Experimental Dermatology

Yoshihide Asano's fields of study encompass medicine broadly, with an emphasis on pathology and forensic medicine and dermatology. Subfields also include immunology, oncology, and epidemiology, reflecting a multidisciplinary approach toward systemic diseases and skin-related disorders.

The main research topics covered in their work include:

  • Systemic Sclerosis and Related Diseases
  • Cutaneous lymphoproliferative disorders research
  • Inflammatory Myopathies and Dermatomyositis
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Autoimmune Bullous Skin Diseases
  • Mast cells and histamine
  • Skin Diseases and Diabetes

Best Publications

  • Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: a multicenter cross-sectional study.

    Yasuhito Hamaguchi;Masataka Kuwana;Kana Hoshino;Minoru Hasegawa

  • Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins.

    Manabu Fujimoto;Yasuhito Hamaguchi;Kenzo Kaji;Takashi Matsushita

  • Increased Expression of Integrin αvβ3 Contributes to the Establishment of Autocrine TGF-β Signaling in Scleroderma Fibroblasts

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Masatoshi Jinnin

  • Impaired Smad7-Smurf–mediated negative regulation of TGF-β signaling in scleroderma fibroblasts

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Masahide Kubo

  • Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial

    Satoshi Ebata;Ayumi Yoshizaki;Koji Oba;Kosuke Kashiwabara

  • Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Masatoshi Jinnin

  • Endothelial Fli1 Deficiency Impairs Vascular Homeostasis : A Role in Scleroderma Vasculopathy

    Yoshihide Asano;Lukasz Stawski;Faye Hant;Kristin Highland

  • Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells.

    Sayaka Shibata;Yayoi Tada;Carren Sy Hau;Aya Mitsui

  • IL-10-producing regulatory B10 cells inhibit intestinal injury in a mouse model.

    Koichi Yanaba;Ayumi Yoshizaki;Yoshihide Asano;Takafumi Kadono

  • Vasculopathy in scleroderma

    Yoshihide Asano;Shinichi Sato

  • Adiponectin Regulates Cutaneous Wound Healing by Promoting Keratinocyte Proliferation and Migration via the ERK Signaling Pathway

    Sayaka Shibata;Yayoi Tada;Yoshihide Asano;Carren S. Hau

  • Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis

    Koichi Yanaba;Ayumi Yoshizaki;Yoshihide Asano;Takafumi Kadono

  • Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1.

    Masatoshi Jinnin;Hironobu Ihn;Yoshihide Asano;Kenichi Yamane

  • Antagonistic Effects of TNF-α on TGF-β Signaling Through Down-Regulation of TGF-β Receptor Type II in Human Dermal Fibroblasts

    Kenichi Yamane;Hironobu Ihn;Yoshihide Asano;Masatoshi Jinnin

  • Future treatments in systemic sclerosis

    Yoshihide Asano

  • Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis

    Ayumi Yoshizaki;Koichi Yanaba;Asako Yoshizaki;Yohei Iwata

  • Transforming Growth Factor-β Regulates DNA Binding Activity of Transcription Factor Fli1 by p300/CREB-binding Protein-associated Factor-dependent Acetylation

    Yoshihide Asano;Joanna Czuwara;Maria Trojanowska

  • Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis

    Shinji Noda;Yoshihide Asano;Satoshi Nishimura;Takashi Taniguchi

  • Clinical significance of surfactant protein D as a serum marker for evaluating pulmonary fibrosis in patients with systemic sclerosis.

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Norihito Yazawa

  • IL-22, but Not IL-17, Dominant Environment in Cutaneous T-cell Lymphoma

    Tomomitsu Miyagaki;Makoto Sugaya;Hiraku Suga;Masahiro Kamata

Frequent Co-Authors

Shinichi Sato
Shinichi Sato University of Tokyo
Takafumi Kadono
Takafumi Kadono St. Marianna University School of Medicine
Hironobu Ihn
Hironobu Ihn Kumamoto University
Kunihiko Tamaki
Kunihiko Tamaki University of Tokyo
Masatoshi Jinnin
Masatoshi Jinnin Wakayama Medical University
Takashi Taniguchi
Takashi Taniguchi National Institute for Materials Science
Koichi Yanaba
Koichi Yanaba Jikei University School of Medicine
Maria Trojanowska
Maria Trojanowska Boston University
Manabu Fujimoto
Manabu Fujimoto Osaka University
Minoru Hasegawa
Minoru Hasegawa University of Fukui

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