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Hironobu Ihn

Hironobu Ihn

D-Index & Metrics

Medicine

D-Index
77
Citations
20830
World Ranking
18471
National Ranking
592

Overview

Hironobu Ihn is affiliated with Kumamoto University in Japan and has contributed extensively to the field of medicine, with a focus on oncology, dermatology, immunology, epidemiology, and pathology. Their research spans various subfields, reflecting a broad and interdisciplinary approach to medical science.

The scientist's work concentrates on key topics such as immunotherapy and immune responses, systemic sclerosis and related diseases, cancer and skin lesions, dermatologic treatments and research, nail diseases and treatments, fungal infections and studies, and vascular tumors and angiosarcomas.

Several recent papers illustrate the scope and focus of Hironobu Ihn's research. These include:

  • Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial, 2020, The Lancet Respiratory Medicine
  • Skin microbiome in acral melanoma: Corynebacterium is associated with advanced melanoma, 2020, The Journal of Dermatology
  • Cutaneous lymphoma in Japan, 2012-2017: A nationwide study, 2020, Journal of Dermatological Science
  • Circulating tumor necrosis factor-α DNA are elevated in psoriasis, 2020, The Journal of Dermatology
  • Significance of 5-S-Cysteinyldopa as a Marker for Melanoma, 2020, International Journal of Molecular Sciences

Hironobu Ihn has frequently published in several notable scientific journals. The most common publication venues include:

  • The Journal of Dermatology
  • Journal of Dermatological Science
  • International Journal of Molecular Sciences
  • Modern Rheumatology
  • Japanese Journal of Clinical Oncology

The scientist has collaborated multiple times with a number of coauthors. Frequently recurring collaborators in their research are:

  • Satoshi Fukushima
  • Ikko Kajihara
  • Katsunari Makino
  • Jun Aoi
  • Hisashi Kanemaru

Hironobu Ihn's extensive publication record includes over 100 works primarily in medicine. The main field of study, medicine, is complemented by significant contributions to oncology, dermatology, immunology, epidemiology, and pathology.

Best Publications

  • Connective Tissue Growth Factor Gene Expression in Tissue Sections From Localized Scleroderma, Keloid, and Other Fibrotic Skin Disorders

    Atsuyuki Igarashi;Kiyoko Nashiro;Kanako Kikuchi;Shinichi Sato

  • Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial.

    Dinesh Khanna;Celia J F Lin;Daniel E Furst;Jonathan Goldin

  • Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-β1-induced extracellular matrix expression

    Masatoshi Jinnin;Hironobu Ihn;Kunihiko Tamaki

  • Pathogenesis of fibrosis: role of TGF-beta and CTGF.

    Hironobu Ihn

  • Significant Correlation Between Connective Tissue Growth Factor Gene Expression and Skin Sclerosis in Tissue Sections from Patients with Systemic Sclerosis

    Atsuyuki Igarashi;Kiyoko Nashiro;Kanako Kikuchi;Shinichi Sato

  • Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment.

    Hirotake Tsukamoto;Koji Fujieda;Azusa Miyashita;Satoshi Fukushima

  • Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype

    Tamihiro Kawakami;Hironobu Ihn;Weidong Xu;Edwin Smith

  • Increased Expression of Integrin αvβ3 Contributes to the Establishment of Autocrine TGF-β Signaling in Scleroderma Fibroblasts

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Masatoshi Jinnin

  • A randomized double-blind trial of intravenous immunoglobulin for pemphigus

    Masayuki Amagai;Shigaku Ikeda;Hiroshi Shimizu;Hajime Iizuka

  • Impaired Smad7-Smurf–mediated negative regulation of TGF-β signaling in scleroderma fibroblasts

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Masahide Kubo

  • Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis

    Nobuyo Higashi-Kuwata;Masatoshi Jinnin;Takamitsu Makino;Satoshi Fukushima

  • Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts

    Taiji Nakashima;Masatoshi Jinnin;Keitaro Yamane;Noritoshi Honda

  • The circulating microRNA-221 level in patients with malignant melanoma as a new tumor marker

    Hisashi Kanemaru;Satoshi Fukushima;Junji Yamashita;Noritoshi Honda

  • Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor β receptors

    Hironobu Ihn;Kenichi Yamane;Masahide Kubo;Kunihiko Tamaki

  • Myasthenic crisis and polymyositis induced by one dose of nivolumab

    Toshihiro Kimura;Satoshi Fukushima;Azusa Miyashita;Jun Aoi

  • Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts

    Yoshihide Asano;Hironobu Ihn;Kenichi Yamane;Masatoshi Jinnin

  • Transcriptional Regulation of the Human α2(I) Collagen Gene COMBINED ACTION OF UPSTREAM STIMULATORY AND INHIBITORY CIS-ACTING ELEMENTS

    Hironobu Ihn;Kazunori Ohnishi;Takeshi Tamaki;E. Carwile LeRoy

  • The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma

    Katsunari Makino;Masatoshi Jinnin;Ayaka Hirano;Keitaro Yamane

  • TGF-β–Mediated Downregulation of MicroRNA-196a Contributes to the Constitutive Upregulated Type I Collagen Expression in Scleroderma Dermal Fibroblasts

    Noritoshi Honda;Masatoshi Jinnin;Ikko Kajihara;Takamitsu Makino

  • Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis

    Minoru Hasegawa;Shinichi Sato;Manabu Fujimoto;Hironobu Ihn

Frequent Co-Authors

Masatoshi Jinnin
Masatoshi Jinnin Wakayama Medical University
Kunihiko Tamaki
Kunihiko Tamaki University of Tokyo
Yoshihide Asano
Yoshihide Asano University of Tokyo
Manabu Fujimoto
Manabu Fujimoto Osaka University
Shinichi Sato
Shinichi Sato University of Tokyo
Minoru Hasegawa
Minoru Hasegawa University of Fukui
Kazuhiko Takehara
Kazuhiko Takehara Kanazawa University
Takafumi Kadono
Takafumi Kadono St. Marianna University School of Medicine
Kazuya Kikuchi
Kazuya Kikuchi Osaka University
Masataka Kuwana
Masataka Kuwana Nippon Medical School

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