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Biology and Biochemistry

D-Index
46
Citations
8360
World Ranking
18920
National Ranking
7728

Overview

Richard A. Katz is affiliated with the Fox Chase Cancer Center in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with a total of 12 publications contributing to these areas. Katz has explored various subfields including Molecular Biology, Immunology, Ocean Engineering, and Oceanography.

The scientist's work spans a range of main topics, prominently featuring Nuclear Structure and Function and Genomics and Chromatin Dynamics, each covered in six publications. Additional research interests include RNA Research and Splicing, Epigenetics and DNA Methylation, Histone Deacetylase Inhibitors Research, CRISPR and Genetic Engineering, and Immunotherapy and Immune Responses.

Among the recent papers authored or coauthored by Katz are:

  • The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting (2020, Journal of Cell Science)
  • PRR14 organizes H3K9me3-modified heterochromatin at the nuclear lamina (2023, Nucleus)
  • HeLa TI cell-based assay as a new approach to screen for chemicals able to reactivate the expression of epigenetically silenced genes (2021, PLoS ONE)
  • Correction to: Thymine DNA glycosylase as a novel target for melanoma (2022, Oncogene)
  • PRR14 organizes H3K9me3-modifed heterochromatin at the nuclear lamina (2022, bioRxiv [Cold Spring Harbor Laboratory])

Frequent coauthors working with Katz include:

  • Andrey Poleshko
  • Anna A. Kiseleva
  • Yu-Chia Cheng
  • Cheryl L. Smith
  • Kelly L. Dunlevy

The publication venues where Katz's work has appeared are diverse, including:

  • Journal of Cell Science
  • Nucleus
  • PLoS ONE
  • Oncogene
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases.

    J. Kulkosky;K. S. Jones;R. A. Katz;J. P. G. Mack

  • The Retroviral Enzymes

    Richard A. Katz;Anna Marie Skalka

  • The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

    Richard A. Katz;George Merkel;Joseph Kulkosky;Jonathan Leis

  • The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration.

    M Katzman;R A Katz;A M Skalka;J Leis

  • Retroviral integrase domains: DNA binding and the recognition of LTR sequences

    Esther Khan;Joseph P.G. Mack;Richard A. Katz;Joseph Kulkosky

  • A role for DNA-PK in retroviral DNA integration.

    René Daniel;Richard A. Katz;Anna Marie Skalka

  • Generation of diversity in retroviruses.

    Richard A. Katz;Anna Marie Skalka

  • High-resolution structure of the catalytic domain of avian sarcoma virus integrase.

    Grzegorz Bujacz;Mariusz Jaskólski;Mariusz Jaskólski;Jerry Alexandratos;Jerry Alexandratos;Alexander Wlodawer;Alexander Wlodawer

  • The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.

    Grzegorz Bujacz;Mariusz Jaskólski;Jerry Alexandratos;Alexander Wlodawer

  • Genome-Wide Analyses of Avian Sarcoma Virus Integration Sites

    Anna Narezkina;Konstantin D. Taganov;Samuel Litwin;Radka Stoyanova

  • Control of retroviral RNA splicing through maintenance of suboptimal processing signals.

    R A Katz;A M Skalka

  • BINDING OF DIFFERENT DIVALENT CATIONS TO THE ACTIVE SITE OF AVIAN SARCOMA VIRUS INTEGRASE AND THEIR EFFECTS ON ENZYMATIC ACTIVITY

    Grzegorz Bujacz;Jerry Alexandratos;Alexander Wlodawer;George Merkel

  • A conserved cis-acting sequence in the 5' leader of avian sarcoma virus RNA is required for packaging.

    R A Katz;R W Terry;A M Skalka

  • KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

    David Frescas;Daniele Guardavaccaro;Shafi M. Kuchay;Hiroyuki Kato

  • Evidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway.

    René Daniel;James G. Greger;Richard A. Katz;Konstantin D. Taganov

  • The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.

    Xiang-Dong Fu;R. A. Katz;A. M. Skalka;T. Maniatis

  • Targeting of Retroviral Integrase by Fusion to a Heterologous DNA Binding Domain:In VitroActivities and Incorporation of a Fusion Protein into Viral Particles

    Richard A. Katz;George Merkel;Anna Marie Skalka

  • Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response

    René Daniel;Gary Kao;Konstantin Taganov;James G. Greger

  • Synthetic peptides as substrates and inhibitors of a retroviral protease

    Moshe Kotler;Richard A. Katz;Waleed Danho;Jonathan Leis

  • cis-acting intron mutations that affect the efficiency of avian retroviral RNA splicing: implication for mechanisms of control.

    R A Katz;M Kotler;A M Skalka

Frequent Co-Authors

Anna Marie Skalka
Anna Marie Skalka Fox Chase Cancer Center
Jonathan Leis
Jonathan Leis Northwestern University
Mariusz Jaskolski
Mariusz Jaskolski Adam Mickiewicz University in Poznań
Alexander Wlodawer
Alexander Wlodawer National Institutes of Health
Rugang Zhang
Rugang Zhang The Wistar Institute
Peter D. Adams
Peter D. Adams Sanford Burnham Prebys Medical Discovery Institute
Alfonso Bellacosa
Alfonso Bellacosa Fox Chase Cancer Center
Irene T. Weber
Irene T. Weber Georgia State University
Lionel Larue
Lionel Larue University of Paris-Saclay
Michele Pagano
Michele Pagano New York University

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