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Genetics

D-Index
70
Citations
19836
World Ranking
2262
National Ranking
1016

Overview

Michael Chandler is affiliated with Georgetown University Medical Center in the United States. Their research spans several interconnected domains within biochemistry, genetics, and molecular biology, with a total of 32 publications in these areas. Additionally, they have contributed to 20 publications in medicine.

The scientist's work is further specialized across multiple subfields, including molecular biology, genetics, molecular medicine, plant science, and epidemiology. The breadth of their research topics reflects a focus on genomics and phylogenetic studies, antibiotic resistance in bacteria, bacterial genetics and biotechnology, and bacteriophages and microbial interactions. Other topics cover chromosomal and genetic variations, veterinary medicine and infectious diseases, and plant pathogenic bacteria studies.

Michael Chandler has published in a variety of venues, showing a pattern of repeated contributions in particular journals. Frequent publication venues include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • Mobile DNA
  • Research and Practice in Thrombosis and Haemostasis

Their recent papers illustrate the scope and focus of their research. Notable publications include:

  • "TnCentral: a Prokaryotic Transposable Element Database and Web Portal for Transposon Analysis," 2021, mBio
  • "The IS6 family, a clinically important group of insertion sequences including IS26," 2021, Mobile DNA
  • "Toxin-Antitoxin Gene Pairs Found in Tn 3 Family Transposons Appear To Be an Integral Part of the Transposition Module," 2020, mBio
  • "TnCentral: A Prokaryotic Transposable Element Database and Web Portal for Transposon Analysis," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "The insertion sequence excision enhancer: A PrimPol-based primer invasion system for immobilizing transposon-transmitted antibiotic resistance genes," 2023, Molecular Microbiology

Collaboration is evident in Michael Chandler's career through frequent co-authors who have appeared multiple times alongside them. These include:

  • Alessandro M. Varani
  • Karen Ross
  • Patricia Siguier
  • Danillo Oliveira Alvarenga
  • Karah Neisen

The interdisciplinary nature of Chandler's work often intersects molecular genetics and medical applications, contributing to understanding antibiotic resistance and transposable elements in bacterial systems. This makes their research relevant to both basic science and clinical contexts, particularly within microbial genetics and biotechnology.

Best Publications

  • ISfinder: the reference centre for bacterial insertion sequences.

    Patricia Siguier;Jocelyne Pérochon;L. Lestrade;J. Mahillon

  • Mobile DNA III

    Nancy Lynn Craig;Michael Chandler;Martin Gellert;Alan M. Lambowitz

  • Genome sequence of the plant pathogen Ralstonia solanacearum

    Marcel Salanoubat;S. Genin;François Artiguenave;J. Gouzy

  • The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens

    Eric Duchaud;Christophe Rusniok;Lionel Frangeul;Carmen Buchrieser

  • Use of gel retardation to analyze protein-nucleic acid interactions.

    D Lane;Pierre Prentki;M Chandler

  • The impact of insertion sequences on bacterial genome plasticity and adaptability

    Joachim Vandecraen;Michael Chandler;Abram Aertsen;Rob Van Houdt

  • Integrating DNA: Transposases and Retroviral Integrases

    L. Haren;B. Ton-Hoang;M. Chandler

  • Insertion Sequences revisited

    Michael Chandler;Jacques Mahillon

  • Insertion sequences in prokaryotic genomes.

    Patricia Siguier;Jonathan Filée;Michael Chandler

  • Revised nomenclature for transposable genetic elements.

    Adam P Roberts;Michael Chandler;Patrice Courvalin;Gérard Guédon

  • Breaking and joining single-stranded DNA: the HUH endonuclease superfamily.

    Michael Chandler;Fernando de la Cruz;Fred Dyda;Alison B. Hickman

  • Functional similarities between retroviruses and the IS3 family of bacterial insertion sequences

    O. Fayet;P. Ramond;P. Polard;M. F. Prère

  • Bacterial transposases and retroviral integrases

    P. Polard;M. Chandler

  • Translational frameshifting in the control of transposition in bacteria.

    Michael Chandler;Olivier Fayet

  • Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition

    Susu He;Alison Burgess Hickman;Alessandro M. Varani;Patricia Siguier

  • A tale of two oxidation states: bacterial colonization of arsenic-rich environments.

    Daniel Muller;Claudine Médigue;Sandrine Koechler;Valérie Barbe

  • Everyman's Guide to Bacterial Insertion Sequences

    Patricia Siguier;Edith Gourbeyre;Alessandro Varani;Bao Ton-Hoang

  • Regulation of transposition in bacteria

    Zita Nagy;Michael Chandler

  • Escherichia coli integration host factor bends the DNA at the ends of IS1 and in an insertion hotspot with multiple IHF binding sites.

    P. Prentki;M. Chandler;D. J. Galas

  • Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti.

    Arjan de Groot;Rémi Dulermo;Philippe Ortet;Laurence Blanchard

Frequent Co-Authors

David J. Galas
David J. Galas Pacific Northwest Diabetes Research Institute
Fred Dyda
Fred Dyda National Institutes of Health
Pascal Gamas
Pascal Gamas Centre national de la recherche scientifique, CNRS
Jacques Mahillon
Jacques Mahillon Université Catholique de Louvain
Valérie Barbe
Valérie Barbe Centre national de la recherche scientifique, CNRS
Laurence Van Melderen
Laurence Van Melderen Université Libre de Bruxelles
Philippe Glaser
Philippe Glaser Institut Pasteur
Claudine Médigue
Claudine Médigue University of Paris-Saclay
Jean Weissenbach
Jean Weissenbach Centre national de la recherche scientifique, CNRS
Douglas E. Berg
Douglas E. Berg Washington University in St. Louis

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