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Biology and Biochemistry

D-Index
74
Citations
20632
World Ranking
5577
National Ranking
157

Overview

Lionel Larue is affiliated with the University of Paris-Saclay in France, with a research focus situated primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work extends across significant subfields including Molecular Biology, Cell Biology, Oncology, Immunology, and Urology.

The scientist's research topics predominantly cover melanin and skin pigmentation, melanoma and MAPK pathways, RNA regulation and disease, genomics and chromatin dynamics, cutaneous melanoma detection and management, hair growth and disorders, and immunotherapy and immune responses.

Among the recent publications are several works closely related to melanoma biology and immunology:

  • ZEB1 transcription factor promotes immune escape in melanoma, 2022, Journal for ImmunoTherapy of Cancer
  • MITF reprograms the extracellular matrix and focal adhesion in melanoma, 2021, eLife
  • STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway, 2020, Oncogene
  • Melanoma Risk and Melanocyte Biology, 2020, Acta Dermato Venereologica
  • MITF and TFEB cross-regulation in melanoma cells, 2020, PLoS ONE

Lionel Larue frequently publishes in venues such as the Journal of Investigative Dermatology, bioRxiv (Cold Spring Harbor Laboratory), Oncogene, Cancers, and Nature.

They have collaborated extensively with coauthors including Zackie Aktary, Véronique Delmas, Valérie Petit, Jérémy H. Raymond, and Eiríkur Steingrímsson.

Best Publications

  • Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways.

    Lionel Larue;Alfonso Bellacosa

  • E-cadherin null mutant embryos fail to form a trophectoderm epithelium

    Lionel Larue;Mami Ohsugi;Jens Hirchenhain;Rolf Kemler

  • Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.

    Salvatore Cortellino;Jinfei Xu;Mara Sannai;Robert Moore

  • Lack of beta-catenin affects mouse development at gastrulation

    Hélène Haegel;Lionel Larue;Mami Ohsugi;Lev Fedorov

  • The Protein Kinase Akt Induces Epithelial Mesenchymal Transition and Promotes Enhanced Motility and Invasiveness of Squamous Cell Carcinoma Lines

    Sylvia Julien Grille;Alfonso Bellacosa;John Upson;Andres J. Klein-Szanto

  • Oncogenic Braf induces melanocyte senescence and melanoma in mice.

    Nathalie Dhomen;Jorge S. Reis-Filho;Silvy da Rocha Dias;Robert Hayward

  • Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

    Suzanne Carreira;Jane Goodall;Laurence Denat;Mercedes Rodriguez

  • Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition.

    S. Julien;I. Puig;E. Caretti;J. Bonaventure

  • Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

    Suzanne Carreira;Jane Goodall;Isil Aksan;S. Anna La Rocca

  • A role for cadherins in tissue formation

    Lionel Larue;Christopher Antos;Stefan Butz;Otmar Huber

  • Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells.

    Maria José Barberà;Maria José Barberà;Isabel Puig;David Domínguez;Sylvia Julien-Grille

  • β-Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development

    Véronique Delmas;Friedrich Beermann;Silvia Martinozzi;Suzanne Carreira

  • MDM4 is a key therapeutic target in cutaneous melanoma

    Agnieszka Gembarska;Agnieszka Gembarska;Flavie Luciani;Flavie Luciani;Clare Fedele;Clare Fedele;Elisabeth A Russell

  • IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition

    Olivier G Morali;Véronique Delmas;Robert Moore;Christine Jeanney

  • The WNT/Beta-catenin pathway in melanoma.

    Lionel Larue;Véronique Delmas

  • Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells

    Mariko Moriyama;Masatake Osawa;Siu-Shan Mak;Toshiyuki Ohtsuka

  • Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia- Associated Transcription Factor-Negative Melanoma Cells

    Jane Goodall;Suzanne Carreira;Laurence Denat;Dominique Kobi

  • A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway

    Christian Praetorius;Christine Grill;Simon N. Stacey;Alexander M. Metcalf

  • Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

    Delphine Javelaud;Khalid S. Mohammad;Christopher R. McKenna;Pierrick Fournier

  • Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.

    G Denecker;N Vandamme;Ö Akay;D Koludrovic

Frequent Co-Authors

Friedrich Beermann
Friedrich Beermann École Polytechnique Fédérale de Lausanne
Alfonso Bellacosa
Alfonso Bellacosa Fox Chase Cancer Center
Eirikur Steingrimsson
Eirikur Steingrimsson University of Iceland
Irwin Davidson
Irwin Davidson Institute of Genetics and Molecular and Cellular Biology
Colin R. Goding
Colin R. Goding University of Oxford
Rolf Kemler
Rolf Kemler Max Planck Society
Dorothy C. Bennett
Dorothy C. Bennett St George's, University of London
Alain Mauviel
Alain Mauviel Institute Curie
Owen J. Sansom
Owen J. Sansom University of Glasgow
Lluís Montoliu
Lluís Montoliu Spanish National Research Council

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