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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Molecular Biology

D-Index
76
Citations
17345
World Ranking
1163
National Ranking
35

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award

Overview

Irwin Davidson is affiliated with the Institute of Genetics and Molecular and Cellular Biology in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology with 92 publications, alongside Medicine, which accounts for 50 publications.

Their work focuses on several key subfields, including Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, and Immunology.

Main topics covered in their research include:

  • Epigenetics and DNA Methylation
  • Ferroptosis and cancer prognosis
  • Renal cell carcinoma treatment
  • Genomics and Chromatin Dynamics
  • Chromatin Remodeling and Cancer
  • Protein Degradation and Inhibitors
  • Renal and related cancers

Selected recent papers authored or coauthored by Irwin Davidson showcase a breadth of research interests and are listed as follows:

  • "Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma," 2020, Cancer Cell
  • "Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease," 2021, Cell Death and Differentiation
  • "Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma," 2020, Gut
  • "Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation," 2021, Nature Communications
  • "Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma," 2023, Cancer Research

Frequent collaborators in Irwin Davidson's research include Guillaume Davidson, Gabriel G. Malouf, Xiaoping Su, Alexandra Helleux, and Véronique Lindner.

Publications have appeared predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Hepatology
  • Cancer Research
  • Cell Death and Disease

Best Publications

  • Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.

    Salvatore Cortellino;Jinfei Xu;Mara Sannai;Robert Moore

  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

    Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub

  • Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1.

    Jia Hao Xiao;Jia Hao Xiao;Irwin Davidson;Irwin Davidson;Hans Matthes;Hans Matthes;Jean-Marie Garnier;Jean-Marie Garnier

  • Melanoma addiction to the long non-coding RNA SAMMSON.

    Eleonora Leucci;Roberto Vendramin;Marco Spinazzi;Patrick Laurette

  • Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

    Xavier Jacq;Xavier Jacq;Christel Brou;Christel Brou;Yves Lutz;Yves Lutz;Irwin Davidson;Irwin Davidson

  • Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription.

    Takayoshi Shimohata;Toshihiro Nakajima;Mitsunori Yamada;Chiharu Uchida

  • seqMINER: an integrated ChIP-seq data interpretation platform

    Tao Ye;Arnaud R Krebs;Mohamed Amin Choukrallah;Céline Keime

  • The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence.

    Irwin Davidson;Irwin Davidson;Jia Hao Xiao;Jia Hao Xiao;Ricardo Rosales;Ricardo Rosales;Adrien Staub;Adrien Staub

  • Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

    Jérôme Govin;Emmanuelle Escoffier;Emmanuelle Escoffier;Sophie Rousseaux;Sophie Rousseaux;Lauriane Kuhn;Lauriane Kuhn;Lauriane Kuhn

  • Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

    T Strub;S Giuliano;T Ye;C Bonet

  • Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis

    Igor Martianov;Stefano Brancorsini;Raffaella Catena;Anne Gansmuller

  • HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

    Nourdine Hamdane;Nourdine Hamdane;Frank Jühling;Frank Jühling;Emilie Crouchet;Emilie Crouchet;Houssein El Saghire;Houssein El Saghire

  • Transcriptional enhancer factor (TEF)-1 and its cell-specific co-activator activate human papillomavirus-16 E6 and E7 oncogene transcription in keratinocytes and cervical carcinoma cells.

    T. Ishiji;M. J. Lace;S. Parkkinen;R. D. Anderson

  • Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia- Associated Transcription Factor-Negative Melanoma Cells

    Jane Goodall;Suzanne Carreira;Laurence Denat;Dominique Kobi

  • Distinct TFIID complexes mediate the effect of different transcriptional activators.

    C Brou;S Chaudhary;I Davidson;Y Lutz

  • Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.

    Mathilde Raverdeau;Aurore Gely-Pernot;Betty Féret;Christine Dennefeld

  • Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

    Benjamin Herquel;Khalid Ouararhni;Konstantin Khetchoumian;Mihaela Ignat

  • Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis

    Noora Kotaja;Sarah Kimmins;Stefano Brancorsini;Didier Hentsch

  • Testis-specific transcription mechanisms promoting male germ-cell differentiation.

    Sarah Kimmins;Noora Kotaja;Irwin Davidson;Paolo Sassone-Corsi

  • Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene.

    Igor Martianov;Gian Maria Fimia;Andrée Dierich;Martti Parvinen

Frequent Co-Authors

Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Laszlo Tora
Laszlo Tora Institute of Genetics and Molecular and Cellular Biology
Lionel Larue
Lionel Larue University of Paris-Saclay
Tao Ye
Tao Ye Pennsylvania State University
Paolo Sassone-Corsi
Paolo Sassone-Corsi University of California, Irvine
Corine Bertolotto
Corine Bertolotto Université Côte d'Azur
Robert Ballotti
Robert Ballotti Université Côte d'Azur
Mirjam B. Zeisel
Mirjam B. Zeisel University of Strasbourg
Martti Parvinen
Martti Parvinen University of Turku
Dino Moras
Dino Moras Institute of Genetics and Molecular and Cellular Biology

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