What is he best known for?
The fields of study he is best known for:
- Gene
- DNA
- Transcription factor
The scientist’s investigation covers issues in Transcription factor, Molecular biology, Genetics, Transcription and Cell biology. His biological study spans a wide range of topics, including Cancer research and Gene expression. His work focuses on many connections between Gene expression and other disciplines, such as Activator, that overlap with his field of interest in TEAD1 and DNA-binding protein.
His Molecular biology research is multidisciplinary, incorporating elements of TAF1, TATA box, TATA-Box Binding Protein, TATA-Binding Protein Associated Factors and Retinoic acid. The Histone, Spermiogenesis, Chromatin and Activating transcription factor 2 research Irwin Davidson does as part of his general Genetics study is frequently linked to other disciplines of science, such as Histone fold, therefore creating a link between diverse domains of science. His work on Enhancer as part of general Transcription research is often related to Neurodegeneration, thus linking different fields of science.
His most cited work include:
- Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. (614 citations)
- Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. (368 citations)
- Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor (355 citations)
What are the main themes of his work throughout his whole career to date?
Irwin Davidson spends much of his time researching Molecular biology, Transcription factor, Cell biology, Genetics and Transcription factor II D. His studies in Molecular biology integrate themes in fields like Transcription Factor TFIID, Promoter and Enhancer, Transcription, Gene. As part of the same scientific family, Irwin Davidson usually focuses on Transcription, concentrating on Activator and intersecting with Psychological repression.
The Transcription factor study combines topics in areas such as Chromatin immunoprecipitation and Melanoma. The study incorporates disciplines such as Chromatin, Cellular differentiation, Retinoid X receptor and Retinoic acid in addition to Cell biology. Irwin Davidson interconnects Protein subunit, RNA polymerase II, General transcription factor and TATA-Box Binding Protein in the investigation of issues within Transcription factor II D.
He most often published in these fields:
- Molecular biology (44.81%)
- Transcription factor (35.52%)
- Cell biology (32.79%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (32.79%)
- Cancer research (14.75%)
- Melanoma (13.66%)
In recent papers he was focusing on the following fields of study:
Irwin Davidson focuses on Cell biology, Cancer research, Melanoma, Transcription factor and Microphthalmia-associated transcription factor. As a member of one scientific family, Irwin Davidson mostly works in the field of Cell biology, focusing on Catenin and, on occasion, Erythropoietin, ARID1A, Transcription, Cell fate determination and Melanoblast. The concepts of his Cancer research study are interwoven with issues in Cell cycle, Epigenetics, Gene and DNA methylation.
Multiplex is closely connected to Cancer in his research, which is encompassed under the umbrella topic of Melanoma. His work carried out in the field of Transcription factor brings together such families of science as Chromatin, Essential gene and Binding site. His work deals with themes such as Acetylation, Protein kinase A, Carcinogenesis, E-box and MAPK/ERK pathway, which intersect with Microphthalmia-associated transcription factor.
Between 2017 and 2021, his most popular works were:
- HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response. (68 citations)
- Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma. (15 citations)
- Thymine DNA glycosylase as a novel target for melanoma (14 citations)
In his most recent research, the most cited papers focused on:
- Gene
- DNA
- Transcription factor
Irwin Davidson mainly focuses on Cancer research, Melanoma, Interferon, Liver cancer and Liver disease. His Cancer research study combines topics from a wide range of disciplines, such as Chromatin, Gene, Somatic evolution in cancer and Innate immune system. His Chromatin study integrates concerns from other disciplines, such as Reprogramming, Essential gene and Transcription factor, SOX10.
His Melanoma research includes elements of Exome sequencing, Missense mutation, Mutation, Genome instability and Chromosome 7. His Interferon research incorporates themes from Cell, Transcriptome, Malignancy and Immune system. His Liver disease study combines topics in areas such as Virus, Immunology, Cirrhosis and Risk factor.
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