D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Genetics and Molecular Biology
France
2022

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 208 Citations 155,004 629 World Ranking 8 National Ranking 1
Best Scientists D-index 250 Citations 221,577 934 World Ranking 36 National Ranking 2

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2022 - Research.com Genetics and Molecular Biology in France Leader Award

2018 - Louisa Gross Horwitz Prize, Columbia University

2010 - Canada Gairdner International Award

2004 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

2003 - Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation

1999 - Louisa Gross Horwitz Prize, Columbia University

1998 - Welch Award in Chemistry, Robert A. Welch Foundation

1994 - Fellow of the American Association for the Advancement of Science (AAAS)

1988 - Member of Academia Europaea

1985 - Fellow of the American Academy of Arts and Sciences

1985 - Member of the National Academy of Sciences

1982 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for their work on fundamental structures of genetic material and of the nervous system.

1979 - CNRS Gold Medal, French National Centre for Scientific Research Biology

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary scientific interests are in Molecular biology, Cell biology, Receptor, Retinoic acid and Endocrinology. Pierre Chambon has researched Molecular biology in several fields, including Gene expression, Transcription factor, Mutant, DNA and Transcription. In his research, Retinoid X receptor gamma, Retinoid and Retinoid X receptor alpha is intimately related to Retinoid X receptor, which falls under the overarching field of Cell biology.

Pierre Chambon works mostly in the field of Receptor, limiting it down to topics relating to Reporter gene and, in certain cases, Glucocorticoid receptor. Pierre Chambon has included themes like Cancer research, Gene isoform and Embryogenesis in his Retinoic acid study. His Endocrinology research includes themes of Peroxisome proliferator-activated receptor, Internal medicine, Estrogen receptor and Mesenchyme.

His most cited work include:

  • The nuclear receptor superfamily: the second decade. (6118 citations)
  • A decade of molecular biology of retinoic acid receptors. (2562 citations)
  • Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A (2075 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Molecular biology, Cell biology, Internal medicine, Endocrinology and Retinoic acid. His studies deal with areas such as Transcription, Transcription factor, Gene expression, Gene and DNA as well as Molecular biology. His work deals with themes such as Promoter, Response element and TATA box, which intersect with Transcription.

His Cell biology research includes elements of Genetics, Receptor, Cellular differentiation, Chromatin and Nuclear receptor. Pierre Chambon combines subjects such as Signal transduction and Estrogen receptor, Estrogen receptor alpha with his study of Endocrinology. His Retinoic acid study deals with Retinoid X receptor intersecting with Retinoid X receptor alpha and Transactivation.

He most often published in these fields:

  • Molecular biology (41.33%)
  • Cell biology (27.66%)
  • Internal medicine (23.79%)

What were the highlights of his more recent work (between 2004-2020)?

  • Endocrinology (23.25%)
  • Internal medicine (23.79%)
  • Cell biology (27.66%)

In recent papers he was focusing on the following fields of study:

Pierre Chambon mainly focuses on Endocrinology, Internal medicine, Cell biology, Estrogen receptor and Estrogen receptor alpha. His research integrates issues of Receptor, Regulation of gene expression and Signal transduction in his study of Endocrinology. His study in Cell biology is interdisciplinary in nature, drawing from both Cellular differentiation, Immunology, Molecular biology, Morphogenesis and Retinoic acid.

His biological study spans a wide range of topics, including Chromatin and Cre recombinase, Genetically modified mouse, Transgene. The Retinoic acid study combines topics in areas such as Nuclear receptor and Retinoid X receptor. The various areas that Pierre Chambon examines in his Estrogen receptor study include Inflammation and Cortical bone.

Between 2004 and 2020, his most popular works were:

  • Estrogen Prevents Bone Loss via Estrogen Receptor α and Induction of Fas Ligand in Osteoclasts (692 citations)
  • FUNCTION OF RETINOID NUCLEAR RECEPTORS: Lessons from Genetic and Pharmacological Dissections of the Retinoic Acid Signaling Pathway During Mouse Embryogenesis (519 citations)
  • Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. (509 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Pierre Chambon mostly deals with Endocrinology, Internal medicine, Cell biology, Retinoic acid and Molecular biology. His studies in Endocrinology integrate themes in fields like Receptor, Signal transduction and Estrogen receptor, Estrogen receptor alpha. Pierre Chambon focuses mostly in the field of Internal medicine, narrowing it down to matters related to Morphogenesis and, in some cases, CD34, Cancer stem cell, Carcinogenesis and Embryo.

His Cell biology study combines topics in areas such as Paracrine signalling, Regulation of gene expression and Cellular differentiation. He interconnects Cancer research and Retinoid X receptor in the investigation of issues within Retinoic acid. His Molecular biology study combines topics from a wide range of disciplines, such as Somatic cell, Alternative splicing, Exon, Chromatin and Genetically modified mouse.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The nuclear receptor superfamily: the second decade.

David J. Mangelsdorf;Carl Thummel;Miguel Beato;Peter Herrlich.
Cell (1995)

8227 Citations

A decade of molecular biology of retinoic acid receptors.

Pierre Chambon.
The FASEB Journal (1996)

4462 Citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

Martin Petkovich;Nigel J. Brand;Andrée Krust;Pierre Chambon.
Nature (1987)

3109 Citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

Stephen Green;Philippe Walter;Vijay Kumar;Andrée Krust.
Nature (1986)

3022 Citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

Shigeaki Kato;Hideki Endoh;Yoshikazu Masuhiro;Takuya Kitamoto.
Science (1995)

2858 Citations

Isolation of high-molecular-weight DNA from mammalian cells.

Maria Gross‐Bellard;Pierre Oudet;Pierre Chambon.
FEBS Journal (1973)

2188 Citations

Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

P Kastner;A Krust;B Turcotte;U Stropp.
The EMBO Journal (1990)

1809 Citations

Functional domains of the human estrogen receptor.

Vijay Kumar;Stephen Green;Gary Stack;Meera Berry.
Cell (1987)

1637 Citations

Nonsteroid nuclear receptors: What Are genetic studies telling us about their role in real life?

Philippe Kastner;Manuel Mark;Pierre Chambon.
Cell (1995)

1508 Citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer.

Vijay Kumar;Pierre Chambon.
Cell (1988)

1485 Citations

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