What is he best known for?
The fields of study he is best known for:
Transcription factor II H, Transcription Factor TFIIH, Molecular biology, Transcription and Nucleotide excision repair are his primary areas of study. His Transcription factor II H study is concerned with the field of Genetics as a whole. His Transcription Factor TFIIH research includes elements of Protein subunit, Transcription factor and RNA polymerase II holoenzyme.
His Molecular biology research incorporates elements of Cell biology, RNA polymerase II, General transcription factor and Transcription factor II D. His Transcription course of study focuses on TATA box and Initiation factor, Enhancer, Yeast, Conserved sequence and Saccharomyces cerevisiae. His research investigates the connection between DNA repair and topics such as DNA damage that intersect with problems in Human skin.
His most cited work include:
- Mammalian DNA nucleotide excision repair reconstituted with purified protein components. (744 citations)
- DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor (683 citations)
- p53 modulation of TFIIH-associated nucleotide excision repair activity. (495 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Molecular biology, Transcription factor II H, Transcription, DNA repair and Transcription Factor TFIIH. His research integrates issues of Transcription factor II B, General transcription factor, RNA polymerase II, Transcription factor II D and RNA polymerase II holoenzyme in his study of Molecular biology. He interconnects Helicase, Transcription factor, Xeroderma pigmentosum and Cell biology in the investigation of issues within Transcription factor II H.
His study in Transcription is interdisciplinary in nature, drawing from both RNA, Regulation of gene expression, Protein subunit and DNA. His study in Nucleotide excision repair and Cockayne syndrome falls under the purview of DNA repair. His Transcription Factor TFIIH study which covers Cyclin-dependent kinase 7 that intersects with Cyclin H and Transactivation.
He most often published in these fields:
- Molecular biology (49.13%)
- Transcription factor II H (45.22%)
- Transcription (37.39%)
What were the highlights of his more recent work (between 2012-2020)?
- Transcription (37.39%)
- DNA repair (30.00%)
- Transcription factor II H (45.22%)
In recent papers he was focusing on the following fields of study:
Jean-Marc Egly focuses on Transcription, DNA repair, Transcription factor II H, Nucleotide excision repair and Molecular biology. His biological study spans a wide range of topics, including RNA, RNA polymerase II and Proteasome. In his work, Cell Cycle Protein and Multiprotein complex is strongly intertwined with Transcriptional regulation, which is a subfield of DNA repair.
His study in Transcription factor II H is interdisciplinary in nature, drawing from both Helicase, Transcription factor, General transcription factor, Trichothiodystrophy and Cyclin-dependent kinase 7. His biological study focuses on Transcription Factor TFIIH. Jean-Marc Egly focuses mostly in the field of Molecular biology, narrowing it down to matters related to Cancer research and, in some cases, Cancer cell.
Between 2012 and 2020, his most popular works were:
- Nucleotide Excision Repair and Transcriptional Regulation: TFIIH and Beyond (82 citations)
- In TFIIH, XPD helicase is exclusively devoted to DNA repair. (59 citations)
- Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack (58 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in DNA repair, Nucleotide excision repair, Transcription, Transcription factor II H and Molecular biology. His DNA repair research is within the category of Gene. Nucleotide excision repair is a subfield of Genetics that Jean-Marc Egly tackles.
His Transcription study combines topics in areas such as RNA polymerase II and Proteasome. He focuses mostly in the field of Transcription factor II H, narrowing it down to topics relating to Helicase and, in certain cases, Transcription factor II A, General transcription factor, RNA polymerase II holoenzyme and Gene expression. His research on Molecular biology frequently links to adjacent areas such as DNA.
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