D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 11,378 112 World Ranking 16047 National Ranking 693

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Genetics

Sandrine Humbert spends much of her time researching Huntingtin, Cell biology, Huntingtin Protein, Dynactin and Dynein. Huntingtin is a primary field of her research addressed under Huntington's disease. Sandrine Humbert has researched Cell biology in several fields, including Arp2/3 complex, Actin cytoskeleton and Cytoskeleton.

Her study with Huntingtin Protein involves better knowledge in Genetics. Her study in Dynein is interdisciplinary in nature, drawing from both Gene silencing, Mitosis and Neuroblast. She interconnects Neurodegeneration and Neuroprotection in the investigation of issues within Phosphorylation.

Her most cited work include:

  • Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules (917 citations)
  • DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor (683 citations)
  • Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation (574 citations)

What are the main themes of her work throughout her whole career to date?

Sandrine Humbert mostly deals with Huntingtin, Cell biology, Huntingtin Protein, Neuroscience and Huntington's disease. The various areas that Sandrine Humbert examines in her Huntingtin study include Cancer research, Neurodegeneration and Phosphorylation. Her Cell biology study frequently draws connections to other fields, such as Biochemistry.

Her Huntingtin Protein research is multidisciplinary, relying on both Molecular biology, Gene silencing, Cancer and Neuroprotection. Her Neuroscience study combines topics from a wide range of disciplines, such as Disease and Anxiety. Her biological study spans a wide range of topics, including Endocrinology, Mutant and Trinucleotide repeat expansion.

She most often published in these fields:

  • Huntingtin (127.52%)
  • Cell biology (67.11%)
  • Huntingtin Protein (61.74%)

What were the highlights of her more recent work (between 2015-2021)?

  • Huntingtin (127.52%)
  • Disease (28.86%)
  • Cell biology (67.11%)

In recent papers she was focusing on the following fields of study:

The scientist’s investigation covers issues in Huntingtin, Disease, Cell biology, Neuroscience and Neurodegeneration. Her study in the field of Huntingtin Protein also crosses realms of Context. Her Disease study incorporates themes from Mutation, Allele, Bioinformatics and Somatic cell.

The Cell biology study combines topics in areas such as Synapse and Induced pluripotent stem cell. Her Neuroscience research includes elements of Cadherin and Transition. Her work carried out in the field of Neurodegeneration brings together such families of science as Gene silencing, Transcriptional regulation, Neuroprotection and Kinase activity.

Between 2015 and 2021, her most popular works were:

  • The Biology of Huntingtin (348 citations)
  • The Biology of Huntingtin (348 citations)
  • Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. (97 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Her primary scientific interests are in Huntingtin, Huntingtin Protein, Neuroscience, Disease and Mutation. Her studies in Huntingtin integrate themes in fields like Neuronal migration, Cortical neurons, Nuclear protein and Phosphorylation. Her research integrates issues of Transgene, Serine, Neurodegeneration, Molecular biology and Toxicity in her study of Huntingtin Protein.

Her Neuroscience research incorporates themes from Cadherin, Transition and Embryogenesis. Her Disease research integrates issues from Genetics, Gene and Function. Her Mutation research is multidisciplinary, relying on both Ciliogenesis, Huntington's disease and Degenerative disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules

Laurent R Gauthier;Bénédicte C Charrin;Maria Borrell-Pagès;Jim P Dompierre.
Cell (2004)

1269 Citations

DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor

Laurent Schaeffer;Richard Roy;Sandrine Humbert;Vincent Moncollin.
Science (1993)

995 Citations

Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation

Jim P. Dompierre;Juliette D. Godin;Bénédicte C. Charrin;Fabrice P. Cordelières.
The Journal of Neuroscience (2007)

819 Citations

The Biology of Huntingtin

Frédéric Saudou;Frédéric Saudou;Sandrine Humbert;Sandrine Humbert.
Neuron (2016)

720 Citations

The IGF-1/Akt Pathway Is Neuroprotective in Huntington's Disease and Involves Huntingtin Phosphorylation by Akt

Sandrine Humbert;Elzbieta A. Bryson;Fabrice P. Cordelières;Nathan C. Connors.
Developmental Cell (2002)

578 Citations

p35 and p39 Are Essential for Cyclin-Dependent Kinase 5 Function during Neurodevelopment

Jane Ko;Sandrine Humbert;Roderick T. Bronson;Satoru Takahashi.
The Journal of Neuroscience (2001)

471 Citations

Cables Links Cdk5 and c-Abl and Facilitates Cdk5 Tyrosine Phosphorylation, Kinase Upregulation, and Neurite Outgrowth

Lawrence R. Zukerberg;Gentry N. Patrick;Margareta Nikolic;Sandrine Humbert.
Neuron (2000)

467 Citations

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

Emilie Colin;Diana Zala;Diana Zala;Géraldine Liot;Géraldine Liot;Hélène Rangone;Hélène Rangone.
The EMBO Journal (2008)

369 Citations

Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis

Juliette D. Godin;Kelly Colombo;Kelly Colombo;Kelly Colombo;Maria Molina-Calavita;Maria Molina-Calavita;Maria Molina-Calavita;Guy Keryer;Guy Keryer;Guy Keryer.
Neuron (2010)

304 Citations

Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.

M Borrell-Pagès;M Borrell-Pagès;D Zala;S Humbert;F Saudou.
Cellular and Molecular Life Sciences (2006)

284 Citations

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