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Best Scientists
2025
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Genetics
France
2026

D-Index & Metrics

Best Scientists

D-Index
169
Citations
127847
World Ranking
904
National Ranking
18

Genetics

D-Index
169
Citations
129157
World Ranking
71
National Ranking
1

Medicine

D-Index
173
Citations
134670
World Ranking
470
National Ranking
12

Research.com Recognitions

  • 2026 - Research.com Genetics in France Leader Award
  • 2026 - Research.com Medicine in France Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Genetics in France Leader Award
  • 2025 - Research.com Medicine in France Leader Award
  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2023 - Research.com Genetics in France Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2023 - Research.com Medicine in France Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in France Leader Award

Overview

Alexis Brice is affiliated with the Institut du Cerveau in France and has contributed extensively to research in medicine, biochemistry, genetics, molecular biology, and neuroscience. Their work primarily spans neurology, molecular biology, cellular and molecular neuroscience, genetics, and physiology.

The scientist's research topics focus on Parkinson's disease mechanisms and treatments, genetic neurodegenerative diseases, neurological diseases and metabolism, mitochondrial function and pathology, nuclear receptors and signaling, neurological disorders and treatments, and amyotrophic lateral sclerosis research.

Frequent publication venues for Alexis Brice include bioRxiv (Cold Spring Harbor Laboratory), Movement Disorders, Brain, npj Parkinson's Disease, and Neurology.

Collaborations have been established with several frequent co-authors including Jean-Christophe Corvol, Suzanne Lesage, Alexandra Dürr, Huw R. Morris, and Andrew Singleton.

Recent notable papers include:

  • Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology, 2021, Nature Genetics
  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome, 2021, Nature Communications
  • Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets, 2021, JAMA Neurology
  • Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease, 2021, Nature Genetics
  • Differences in the Presentation and Progression of Parkinson's Disease by Sex, 2020, Movement Disorders

Alexis Brice has authored a book published by Springer International Publishing titled Trials for Cerebellar Ataxias in 2023.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

    Vincenzo Bonifati;Vincenzo Bonifati;Patrizia Rizzu;Marijke J. van Baren;Onno Schaap

  • Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

    Victoria Campuzano;Laura Montermini;Maria Dolores Moltò;Luigi Pianese

  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

    Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

    Mike A Nalls;Nathan Pankratz;Christina M. Lill;Chuong B. Do

  • Association between Early-Onset Parkinson's Disease and Mutations in the Parkin Gene

    CB Lucking;A Durr;Bonifati;J Vaughan

  • Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

    Daniel G Healy;Mario Falchi;Sean S O'Sullivan;Vincenzo Bonifati

  • APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

    Anne Rovelet-Lecrux;Didier Hannequin;Gregory Raux;Nathalie Le Meur

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

    Elisa Majounie;Alan E. Renton;Kin Mok;Elise G. P. Dopper;Elise G. P. Dopper

  • Causal relation between α-synuclein locus duplication as a cause of familial Parkinson's disease

    P Ibáñez;A-M Bonnet;B Débarges;E Lohmann

  • Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2.

    Andrew Escayg;Bryan T. MacDonald;Miriam H. Meisler;Stéphanie Baulac

  • Clinical and Genetic Abnormalities in Patients with Friedreich's Ataxia

    Alexandra Dürr;Mireille Cossee;Yves Agid;Victoria Campuzano

  • Parkinson's disease: from monogenic forms to genetic susceptibility factors

    Suzanne Lesage;Alexis Brice

  • Early-Onset Autosomal Dominant Alzheimer Disease: Prevalence, Genetic Heterogeneity, and Mutation Spectrum

    Dominique Campion;Cécile Dumanchin;Didier Hannequin;Bruno Dubois

  • First genetic evidence of GABA(A) receptor dysfunction in epilepsy: a mutation in the gamma2-subunit gene.

    Stéphanie Baulac;Gilles Huberfeld;Isabelle Gourfinkel-An;Georgia Mitropoulou

  • Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

    Georges Imbert;Frédéric Saudou;Frédéric Saudou;Gaël Yvert;Gaël Yvert;Didier Devys;Didier Devys

  • Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.

    Michael A Nalls;Vincent Plagnol;Dena G Hernandez

Frequent Co-Authors

Alexandra Durr
Alexandra Durr Sorbonne University
Giovanni Stevanin
Giovanni Stevanin Inserm : Institut national de la santé et de la recherche médicale
Yves Agid
Yves Agid Institut du Cerveau
Didier Hannequin
Didier Hannequin Grenoble Alpes University
Thomas Gasser
Thomas Gasser University of Tübingen
Eric LeGuern
Eric LeGuern Institut du Cerveau
Suzanne Lesage
Suzanne Lesage Université Paris Cité
Nicholas W. Wood
Nicholas W. Wood University College London
Peter Heutink
Peter Heutink German Center for Neurodegenerative Diseases
Andrew B. Singleton
Andrew B. Singleton National Institutes of Health

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