D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 89 Citations 36,913 263 World Ranking 659 National Ranking 373
Medicine D-index 79 Citations 29,697 312 World Ranking 9879 National Ranking 5319

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Internal medicine

His primary scientific interests are in Genetics, Parkinsonism, LRRK2, Parkinson's disease and Mutation. Many of his studies involve connections with topics such as Disease and Genetics. His work carried out in the field of Disease brings together such families of science as Pathological, Neuroscience and Gene.

His study on Parkinsonism is covered under Pathology. His research integrates issues of Bioinformatics, Allele frequency and Risk factor in his study of LRRK2. His Mutation course of study focuses on Parkin and Ubiquitin ligase.

His most cited work include:

  • α-Synuclein Locus Triplication Causes Parkinson's Disease (3413 citations)
  • Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology (2198 citations)
  • α-synuclein locus duplication as a cause of familial Parkinson's disease (1526 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Genetics, Parkinson's disease, Parkinsonism, Disease and LRRK2. His is involved in several facets of Genetics study, as is seen by his studies on Mutation, Gene, Haplotype, Locus and Allele. His work deals with themes such as Endocrinology, Case-control study and Allele frequency, which intersect with Parkinson's disease.

His research in Parkinsonism focuses on subjects like Parkin, which are connected to Compound heterozygosity. His Disease study incorporates themes from Phenotype, Pathological, Neuroscience and Bioinformatics. His LRRK2 study combines topics from a wide range of disciplines, such as Penetrance and Kinase.

He most often published in these fields:

  • Genetics (51.16%)
  • Parkinson's disease (34.11%)
  • Parkinsonism (33.53%)

What were the highlights of his more recent work (between 2014-2021)?

  • Parkinson's disease (34.11%)
  • Parkinsonism (33.53%)
  • Genetics (51.16%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Parkinson's disease, Parkinsonism, Genetics, Disease and LRRK2. His Parkinson's disease research is multidisciplinary, incorporating elements of Dopaminergic, Allele, Genetic predisposition and Pathogenesis. His Parkinsonism study improves the overall literature in Pathology.

The study incorporates disciplines such as Phenotype, Psychiatry, Neuroscience and Cohort in addition to Disease. His LRRK2 study integrates concerns from other disciplines, such as Penetrance, Risk factor, Vacuolar protein sorting and Cell biology. His Alpha-synuclein research focuses on Kinase and how it relates to Synuclein.

Between 2014 and 2021, his most popular works were:

  • Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice (125 citations)
  • Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N (92 citations)
  • Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism. (80 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Mutation

Matthew J. Farrer spends much of his time researching Parkinsonism, Genetics, Parkinson's disease, Internal medicine and Disease. His Parkinsonism study introduces a deeper knowledge of Pathology. His study in Mutation, Proband, Genetic heterogeneity and Haplotype falls under the purview of Genetics.

As part of one scientific family, Matthew J. Farrer deals mainly with the area of Parkinson's disease, narrowing it down to issues related to the VPS35, and often Cell biology. Matthew J. Farrer combines subjects such as Endocrinology and Oncology with his study of Internal medicine. His Disease research includes themes of Biomarker, Phenotype, Odds ratio and Bioinformatics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

α-Synuclein Locus Triplication Causes Parkinson's Disease

A. B. Singleton;M. Farrer;J. Johnson;A. Singleton.
Science (2003)

4141 Citations

Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich;Alexander Zimprich;Saskia Biskup;Petra Leitner;Peter Lichtner.
Neuron (2004)

2665 Citations

α-synuclein locus duplication as a cause of familial Parkinson's disease

Marie-Christine Chartier-Harlin;Jennifer M. Kachergus;Christophe Roumier;Vincent Mouroux.
The Lancet (2004)

2020 Citations

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz.
The New England Journal of Medicine (2009)

1592 Citations

Genetics of Parkinson disease: paradigm shifts and future prospects.

Matthew James Farrer.
Nature Reviews Genetics (2006)

837 Citations

Missing pieces in the Parkinson's disease puzzle.

Jose A Obeso;Maria C Rodriguez-Oroz;Christopher G Goetz;Concepcion Marin;Concepcion Marin.
Nature Medicine (2010)

819 Citations

VPS35 Mutations in Parkinson Disease

Carles Vilariño-Güell;Christian Wider;Owen A. Ross;Justus C. Dachsel.
American Journal of Human Genetics (2011)

803 Citations

Comparison of kindreds with parkinsonism and α‐synuclein genomic multiplications

Matt Farrer;Jennifer Kachergus;Lysia Forno;Sarah Lincoln.
Annals of Neurology (2004)

756 Citations

Parkin Protects against the Toxicity Associated with Mutant α-Synuclein: Proteasome Dysfunction Selectively Affects Catecholaminergic Neurons

Leonard Petrucelli;Casey O'Farrell;Paul J. Lockhart;Melisa Baptista.
Neuron (2002)

670 Citations

α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins

Natalie Ostrerova;Leonard Petrucelli;Matthew Farrer;Nitinkumar Mehta.
The Journal of Neuroscience (1999)

654 Citations

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