What is he best known for?
The fields of study he is best known for:
- Gene
- Genetics
- Internal medicine
His primary scientific interests are in Genetics, Parkinsonism, LRRK2, Parkinson's disease and Mutation.
Many of his studies involve connections with topics such as Disease and Genetics.
His work carried out in the field of Disease brings together such families of science as Pathological, Neuroscience and Gene.
His study on Parkinsonism is covered under Pathology.
His research integrates issues of Bioinformatics, Allele frequency and Risk factor in his study of LRRK2.
His Mutation course of study focuses on Parkin and Ubiquitin ligase.
His most cited work include:
- α-Synuclein Locus Triplication Causes Parkinson's Disease (3413 citations)
- Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology (2198 citations)
- α-synuclein locus duplication as a cause of familial Parkinson's disease (1526 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Genetics, Parkinson's disease, Parkinsonism, Disease and LRRK2.
His is involved in several facets of Genetics study, as is seen by his studies on Mutation, Gene, Haplotype, Locus and Allele.
His work deals with themes such as Endocrinology, Case-control study and Allele frequency, which intersect with Parkinson's disease.
His research in Parkinsonism focuses on subjects like Parkin, which are connected to Compound heterozygosity.
His Disease study incorporates themes from Phenotype, Pathological, Neuroscience and Bioinformatics.
His LRRK2 study combines topics from a wide range of disciplines, such as Penetrance and Kinase.
He most often published in these fields:
- Genetics (51.16%)
- Parkinson's disease (34.11%)
- Parkinsonism (33.53%)
What were the highlights of his more recent work (between 2014-2021)?
- Parkinson's disease (34.11%)
- Parkinsonism (33.53%)
- Genetics (51.16%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Parkinson's disease, Parkinsonism, Genetics, Disease and LRRK2.
His Parkinson's disease research is multidisciplinary, incorporating elements of Dopaminergic, Allele, Genetic predisposition and Pathogenesis.
His Parkinsonism study improves the overall literature in Pathology.
The study incorporates disciplines such as Phenotype, Psychiatry, Neuroscience and Cohort in addition to Disease.
His LRRK2 study integrates concerns from other disciplines, such as Penetrance, Risk factor, Vacuolar protein sorting and Cell biology.
His Alpha-synuclein research focuses on Kinase and how it relates to Synuclein.
Between 2014 and 2021, his most popular works were:
- Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice (125 citations)
- Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N (92 citations)
- Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism. (80 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Mutation
Matthew J. Farrer spends much of his time researching Parkinsonism, Genetics, Parkinson's disease, Internal medicine and Disease.
His Parkinsonism study introduces a deeper knowledge of Pathology.
His study in Mutation, Proband, Genetic heterogeneity and Haplotype falls under the purview of Genetics.
As part of one scientific family, Matthew J. Farrer deals mainly with the area of Parkinson's disease, narrowing it down to issues related to the VPS35, and often Cell biology.
Matthew J. Farrer combines subjects such as Endocrinology and Oncology with his study of Internal medicine.
His Disease research includes themes of Biomarker, Phenotype, Odds ratio and Bioinformatics.
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