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Genetics

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108
Citations
52959
World Ranking
564
National Ranking
281

Medicine

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114
Citations
58151
World Ranking
4661
National Ranking
2533

Overview

Matthew J. Farrer is affiliated with the University of Florida in the United States. Their research activity primarily focuses on various aspects of Parkinson's disease, including mechanisms, treatments, and related neurological processes. The scientist's work spans multiple disciplines such as medicine, biochemistry, genetics, molecular biology, and neuroscience.

Farrer's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

The subfields of study in which they have contributed notably are:

  • Neurology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Genetics
  • Physiology

The principal research topics covered in their publications are:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological diseases and metabolism
  • RNA regulation and disease
  • Nuclear Receptors and Signaling
  • Lysosomal Storage Disorders Research
  • Cellular transport and secretion
  • Neurological disorders and treatments

Frequently publishing in venues specializing in neurodegenerative diseases and neuroscience, Farrer's common publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Movement Disorders
  • npj Parkinson s Disease
  • Research Square (Research Square)

Notable papers from Matthew J. Farrer include:

  • "The Gut-Brain Axis and Its Relation to Parkinson's Disease: A Review" (2022) in Frontiers in Aging Neuroscience
  • "Disease modification and biomarker development in Parkinson disease" (2020) in Neurology
  • "Variants in saposin D domain of prosaposin gene linked to Parkinson's disease" (2020) in Brain
  • "Dynamic control of the dopamine transporter in neurotransmission and homeostasis" (2021) in npj Parkinson s Disease
  • "RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses" (2024) in The Lancet Neurology

They have collaborated frequently with several researchers, including:

  • Jordan Follett
  • Joanne Trinh
  • Alexis Brice
  • Christine Klein
  • Nobutaka Hattori

Best Publications

  • α-Synuclein Locus Triplication Causes Parkinson's Disease

    A. B. Singleton;M. Farrer;J. Johnson;A. Singleton

  • Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

    Alexander Zimprich;Alexander Zimprich;Saskia Biskup;Petra Leitner;Peter Lichtner

  • α-synuclein locus duplication as a cause of familial Parkinson's disease

    Marie-Christine Chartier-Harlin;Jennifer M. Kachergus;Christophe Roumier;Vincent Mouroux

  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

    Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz

  • VPS35 Mutations in Parkinson Disease

    Carles Vilariño-Güell;Christian Wider;Owen A. Ross;Justus C. Dachsel

  • Missing pieces in the Parkinson's disease puzzle.

    Jose A Obeso;Maria C Rodriguez-Oroz;Christopher G Goetz;Concepcion Marin;Concepcion Marin

  • Genetics of Parkinson disease: paradigm shifts and future prospects.

    Matthew James Farrer

  • Comparison of kindreds with parkinsonism and α‐synuclein genomic multiplications

    Matt Farrer;Jennifer Kachergus;Lysia Forno;Sarah Lincoln

  • Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease

    Silke Appel-Cresswell;Carles Vilarino-Guell;Mary Encarnacion;Holly Sherman

  • Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons.

    Leonard Petrucelli;Casey O'Farrell;Paul J. Lockhart;Melisa Baptista

  • α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins

    Natalie Ostrerova;Leonard Petrucelli;Matthew Farrer;Nitinkumar Mehta

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Lewy bodies and parkinsonism in families with parkin mutations.

    M Farrer;P Chan;R Chen;L Tan

  • Identification of a Novel LRRK2 Mutation Linked to Autosomal Dominant Parkinsonism: Evidence of a Common Founder across European Populations

    Jennifer Kachergus;Ignacio F. Mata;Mary Hulihan;Julie P. Taylor

  • Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.

    Demetrius M. Maraganore;Mariza De Andrade;Alexis Elbaz;Matthew J. Farrer

  • High-Resolution Whole-Genome Association Study of Parkinson Disease

    Demetrius M. Maraganore;Mariza de Andrade;Timothy G. Lesnick;Kari J. Strain

  • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database.

    Christina M. Lill;Johannes T. Roehr;Johannes T. Roehr;Matthew B. McQueen;Fotini K. Kavvoura;Fotini K. Kavvoura;Fotini K. Kavvoura

  • LRRK2 in Parkinson's disease: protein domains and functional insights.

    Ignacio F. Mata;William J. Wedemeyer;Matthew J. Farrer;Julie P. Taylor

  • Advances in the genetics of Parkinson disease

    Joanne Trinh;Matt Farrer

  • Molecular mapping of alzheimer-type dementia in Down's syndrome

    V. P. Prasher;Matthew J. Farrer;Anna M. Kessling;Elizabeth M. C. Fisher

Frequent Co-Authors

Owen A. Ross
Owen A. Ross Mayo Clinic
Sarah Lincoln
Sarah Lincoln Mayo Clinic
Ryan J. Uitti
Ryan J. Uitti Mayo Clinic
John Hardy
John Hardy University College London
Demetrius M. Maraganore
Demetrius M. Maraganore Tulane University
Thomas Gasser
Thomas Gasser University of Tübingen
Alexis Brice
Alexis Brice Institut du Cerveau
Nobutaka Hattori
Nobutaka Hattori Juntendo University

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