Sarah Lincoln mainly investigates Genetics, Parkinsonism, Mutation, Missense mutation and Haplotype. Her Genetics study combines topics from a wide range of disciplines, such as Frontotemporal lobar degeneration, Parkinson's disease and Pathology. Alpha-synuclein is the focus of her Parkinson's disease research.
Her Parkinsonism research is multidisciplinary, relying on both Lewy body, Dementia, Proband, Autosomal dominant trait and LRRK2. Her biological study spans a wide range of topics, including Splice site mutation and Synucleinopathies. Her work deals with themes such as Candidate gene and Exon, which intersect with Mutation.
Her scientific interests lie mostly in Genetics, Disease, Parkinsonism, Gene and Parkinson's disease. Many of her studies involve connections with topics such as Parkin and Genetics. Sarah Lincoln usually deals with Disease and limits it to topics linked to Transcriptome and Cell type.
Sarah Lincoln has researched Parkinsonism in several fields, including Lewy body, Missense mutation, Proband, Substantia nigra and LRRK2. Her Parkinson's disease research integrates issues from Genetic variation, Polymorphism and Degenerative disease. Her work in Alpha-synuclein tackles topics such as Synuclein which are related to areas like Beta-synuclein.
Her primary areas of study are Disease, Genetics, Transcriptome, Gene and Computational biology. Sarah Lincoln has included themes like Neurology, Immunology and Genotype in her Disease study. Her Neurology study integrates concerns from other disciplines, such as Gastroenterology, Missense mutation and Autopsy.
Her Genetics research incorporates elements of Temporal cortex and Disease risk. Her Transcriptome study also includes fields such as
Alzheimer's disease, Temporal cortex, Genetics, Transcriptome and Neuropathology are her primary areas of study. She has included themes like Exome sequencing, Genetic association and Exon in her Alzheimer's disease study. Her biological study spans a wide range of topics, including Progressive supranuclear palsy, Reduced representation bisulfite sequencing, Single-nucleotide polymorphism, Epigenetics and CpG site.
Her work often combines Genetics and Hypersensitive site studies. Her work in Transcriptome covers topics such as Cell type which are related to areas like Tauopathy and Cerebellum. She combines subjects such as Posterior cortical atrophy, Dementia, Frontotemporal dementia, Bioinformatics and Exome with her study of Neuropathology.
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α-Synuclein Locus Triplication Causes Parkinson's Disease
A. B. Singleton;M. Farrer;J. Johnson;A. Singleton.
Science (2003)
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
M. Hutton;C. L. Lendon;P. Rizzu;M. Baker.
Nature (1998)
Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology
Alexander Zimprich;Alexander Zimprich;Saskia Biskup;Petra Leitner;Peter Lichtner.
Neuron (2004)
α-synuclein locus duplication as a cause of familial Parkinson's disease
Marie-Christine Chartier-Harlin;Jennifer M. Kachergus;Christophe Roumier;Vincent Mouroux.
The Lancet (2004)
VPS35 Mutations in Parkinson Disease
Carles Vilariño-Güell;Christian Wider;Owen A. Ross;Justus C. Dachsel.
American Journal of Human Genetics (2011)
Comparison of kindreds with parkinsonism and α‐synuclein genomic multiplications
Matt Farrer;Jennifer Kachergus;Lysia Forno;Sarah Lincoln.
Annals of Neurology (2004)
Lewy bodies and parkinsonism in families with parkin mutations.
M Farrer;P Chan;R Chen;L Tan.
Annals of Neurology (2001)
Identification of a Novel LRRK2 Mutation Linked to Autosomal Dominant Parkinsonism: Evidence of a Common Founder across European Populations
Jennifer Kachergus;Ignacio F. Mata;Mary Hulihan;Julie P. Taylor.
American Journal of Human Genetics (2005)
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
Demetrius M. Maraganore;Mariza De Andrade;Alexis Elbaz;Matthew J. Farrer.
JAMA (2006)
A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1
Richard Crook;Auli Verkkoniemi;Jordi Perez-Tur;Nitin Mehta.
Nature Medicine (1998)
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